The leukocytes

The Veterinary Clinics of North America. Small Animal Practice
J G Zinkl

Abstract

Dogs and cats respond to many diseases by changes in leukocyte numbers. Infectious diseases often cause leukocytosis due to neutrophilia. Left shift may accompany the leukocytosis, indicating that the marrow is mounting a response to the disease. Left shift also indicates that the marrow has fallen somewhat behind the needs of the animal. Degenerative left shift is considered a poor sign. Lymphopenia and eosinopenia also are found in infectious diseases. Lymphocytosis may occur during the recovery or if the disease becomes chronic. The nature and duration of the infection determine the magnitude of the monocyte response. It is erroneous to consider a disease chronic based only upon monocytosis. Trauma, autoimmunity, or any disease with significant tissue destruction can evoke a monocyte response. Leukopenias are relatively common in cats and are found with moderate frequency in dogs. Drugs, viral diseases (such as FeLV, feline enteritis, parvovirus), ehrlichiosis, and hereditary conditions may cause panleukopenias or single leukopenias. Occasionally leukocyte examination provides evidence of a specific etiology (such as with ehrlichiosis). Sometimes changes occur which, although not specific for a disease, may provide a strong ...Continue Reading

References

Nov 1, 1979·The Journal of Small Animal Practice·A D Watson
Dec 1, 1974·Journal of Autism and Childhood Schizophrenia·D Park, P Youderian
Nov 1, 1974·Australian Veterinary Journal·J W Copland
Jan 31, 1980·The New England Journal of Medicine·G H LymanD Preston
Jun 1, 1980·The Journal of Clinical Investigation·D A BassC E McCall

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Citations

Jan 31, 2012·The Veterinary Clinics of North America. Small Animal Practice·Amy N Schnelle, Anne M Barger
Mar 7, 2014·Journal of Veterinary Internal Medicine·A G BurtonK E Jandrey
Oct 15, 2013·Journal of Veterinary Internal Medicine·A G BurtonK E Jandrey
Jun 8, 2002·Toxicologic Pathology·Lilian Calderón-GarcidueñasBarry Rewcastle

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