Dec 1, 1975

The lichen planus-like eruption after bone marrow transplantation

The British Journal of Dermatology
J H SauratA Puissant


A lichen planus-like eruption was seen in four patients after bone marrow transplantation. The skin and mucous membrane appearance closely mimicked lichen planus. The histopathology was also very similar to lichen planus. The occurrence of a lichen planus-like eruption (LPLE) after an immune basal cell damage related to the graft-versus-host reaction raised the question of the immune nature of this eruption. The correlation found between biological signs of graft-versus-host reaction and the out-break or relapse of the lichen planus-like eruption supports the hypothesis that the skin changes could be a sign of a chronic immune response against recipient epidermis.

  • References5
  • Citations57


Mentioned in this Paper

Immune Response
Bone Marrow
Transplantation Immunology
Graft Vs Host Reaction
Histopathological Aspects
Pregnancy Related Skin Change
Lichen Planus
Muscularis Mucosae

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