The Lifespan Human Connectome Project in Development: A large-scale study of brain connectivity development in 5-21 year olds

NeuroImage
Leah H SomervilleDeanna M Barch

Abstract

Recent technological and analytical progress in brain imaging has enabled the examination of brain organization and connectivity at unprecedented levels of detail. The Human Connectome Project in Development (HCP-D) is exploiting these tools to chart developmental changes in brain connectivity. When complete, the HCP-D will comprise approximately ∼1750 open access datasets from 1300 + healthy human participants, ages 5-21 years, acquired at four sites across the USA. The participants are from diverse geographical, ethnic, and socioeconomic backgrounds. While most participants are tested once, others take part in a three-wave longitudinal component focused on the pubertal period (ages 9-17 years). Brain imaging sessions are acquired on a 3 T Siemens Prisma platform and include structural, functional (resting state and task-based), diffusion, and perfusion imaging, physiological monitoring, and a battery of cognitive tasks and self-reports. For minors, parents additionally complete a battery of instruments to characterize cognitive and emotional development, and environmental variables relevant to development. Participants provide biological samples of blood, saliva, and hair, enabling assays of pubertal hormones, health markers,...Continue Reading

Associated Datasets

Citations

Mar 28, 2020·Human Brain Mapping·Sila GencDerek K Jones
Jun 17, 2020·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Nicole R Karcher, Deanna M Barch
Dec 23, 2020·Journal of Developmental Origins of Health and Disease·G D ClarkeP W Nathanielsz
Jul 23, 2020·Computational and Structural Biotechnology Journal·Dae-Jin Kim, Byoung-Kyong Min
Nov 25, 2020·Neurotoxicology and Teratology·Donovan J RoedigerJeffrey R Wozniak
Nov 24, 2020·Neurobiology of Aging·Amy N MurrayThomas M Lancaster
May 1, 2020·Trends in Neurosciences·Katherine H Karlsgodt
Mar 21, 2021·NeuroImage. Clinical·Shinsuke KoikeUNKNOWN Brain/MINDS Beyond Human Brain MRI Group
Sep 18, 2020·Developmental Cognitive Neuroscience·Sara Sanchez-Alonso, Richard N Aslin
Oct 15, 2020·The European Journal of Neuroscience·Madeline J FarberAhmad R Hariri
Apr 1, 2021·Biometrics·Bingxin Zhao, Fei Zou
May 10, 2021·Journal of the American Academy of Child and Adolescent Psychiatry·Randy P AuerbachDiego A Pizzagalli
Jun 21, 2021·Developmental Cognitive Neuroscience·Sadie J ZacharekDylan G Gee
Jul 17, 2021·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Leon Y CaiBennett A Landman
Aug 10, 2021·Frontiers in Psychiatry·Benjamin A ElyVilma Gabbay
Sep 12, 2021·NeuroImage·Jennifer Stine ElamDavid C Van Essen

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