The lifetime risk of pneumonia in patients with neuromuscular scoliosis at a mean age of 21 years: the role of spinal deformity surgery

Journal of Children's Orthopaedics
Heli KeskinenIlkka Helenius

Abstract

Patients with neuromuscular disorders often have an increased risk of pneumonia and decreased lung function, which may further be compromised by scoliosis. Scoliosis surgery may improve pulmonary function in otherwise healthy patients, but no study has evaluated its effect on the risk of pneumonia in patients with neuromuscular scoliosis (NMS). The patient charts of 42 patients (mean age 14.6 years) who had undergone surgery for severe NMS (mean scoliosis 86°) were retrospectively reviewed from birth to a mean of 6.1 years (range 2.8-9.5) after scoliosis surgery. The main outcome was radiographically confirmed pneumonia as a primary cause for hospitalization. We excluded postoperative (3 months) pneumonia from the analyses. The lifetime annual incidence of pneumonia was 8.0/100 before and 13.4/100 after scoliosis surgery (p > 0.10). The mean number of hospital days per year due to pneumonia were 0.59 (SD 2.3) before scoliosis surgery and 2.24 (SD 6.9) after surgery (p > 0.10). Multivariate analysis demonstrated that lifetime risk factors for pneumonia were epilepsy (RR 15.2, 95 % CI 1.3-176.8, p = 0.027), non-cerebral palsy (CP) etiology (RR = 10.2, 95 % CI 3.2-32.7, p < 0.001) and major scoliosis (main curve >70°; RR = 11.3, 9...Continue Reading

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Citations

Oct 16, 2018·Developmental Medicine and Child Neurology·Lieve BoelStijn Verhulst
Jul 6, 2019·Child: Care, Health and Development·Amanda Marie BlackmoreAndrew C Wilson
Mar 14, 2020·Journal of Children's Orthopaedics·Ilkka J HeleniusRene M Castelein
Jul 17, 2020·Frontiers in Pediatrics·Rachael MarpoleAndrew C Wilson
Aug 18, 2020·Developmental Medicine and Child Neurology·Noula GibsonAndrew C Wilson
Dec 29, 2020·Asian Spine Journal·Karen Andrea WeissmannRonald G Schulz
Aug 20, 2021·Archives of Disease in Childhood·Katherine Lehovsky

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