THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS

Jan 1, 1997·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·M KassemS I Rattan

How do mutated oncogenes and tumor suppressor genes cause cancer?

Jun 27, 1998·Medical Oncology·D Grandér

Induction of myosin light chain synthesis in heterokaryons between normal diploid cells

Oct 1, 1982·In Vitro·W E Wright

Ultrastructure and surface topography of aggregates of human limb mesenchymal cells (HLM15) in vitro

Feb 1, 1976·In Vitro·R O Kelley, R B Lauer

A model culture system with human gingival fibroblasts for evaluating the cytotoxicity of dental materials

Jul 1, 1982·In Vitro·F H KastenT Alchediak

Effects of feeder layers made of human, mouse, hamster, and rat cells on the cloning efficiency of transformed human cells

May 1, 1982·In Vitro·M NambaT Kimoto

Proliferative capacity of cell cultures derived from the human placenta

Sep 11, 1976·In Vitro·R A VincentT H Parmley

Atmospheric stability in cell culture vessels

Oct 1, 1976·In Vitro·A K BalinV J Cristofalo

Effects of methanolic extracts from broad beans on cellular growth and antioxidant enzyme activity

Nov 1, 2007·Environmental Health and Preventive Medicine·Mizue Okada, Yoshinori Okada

Target population for clinical trials on sarcopenia

Jul 11, 2008·The Journal of Nutrition, Health & Aging·M Cesari, M Pahor

A decrease in hyaluronic acid synthesis by aging human fibroblasts leading to heparan sulfate enrichment and growth reduction

Sep 1, 1989·Aging : Clinical and Experimental Research·K MatuokaY Mitsui

From old organisms to new molecules: integrative biology and therapeutic targets in accelerated human ageing

Jul 31, 2007·Cellular and Molecular Life Sciences : CMLS·L S Cox, R G Faragher

Histone deacetylase controls adult stem cell aging by balancing the expression of polycomb genes and jumonji domain containing 3

Jan 6, 2010·Cellular and Molecular Life Sciences : CMLS·Ji-Won JungKyung-Sun Kang

Skin aging

Nov 10, 2009·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·E KohlR-M Szeimies

Molecular etiology of skin aging. How important is the genetic make-up?

Jun 18, 2011·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·E Makrantonaki, C C Zouboulis

Novel ARF/p53-independent senescence pathways in cancer repression

May 20, 2011·Journal of Molecular Medicine : Official Organ of the Gesellschaft Deutscher Naturforscher Und Ärzte·Chia-Hsin ChanHui-Kuan Lin

Genetic variants implicated in telomere length associated with left ventricular function in patients with hypertension and cardiac organ damage

Feb 9, 2012·Journal of Molecular Medicine : Official Organ of the Gesellschaft Deutscher Naturforscher Und Ärzte·Matthias HuberReinhold Kreutz

Gap junctional intercellular communication as a biological "Rosetta stone" in understanding, in a systems biological manner, stem cell behavior, mechanisms of epigenetic toxicology, chemoprevention and chemotherapy

Oct 26, 2007·The Journal of Membrane Biology·J E Trosko

Vessel aging. The role of oxidative stress and protein glycation

Jun 17, 2011·Zeitschrift für Gerontologie und Geriatrie·A Simm

Senescence-associated alterations of cytoskeleton: extraordinary production of vimentin that anchors cytoplasmic p53 in senescent human fibroblasts

Mar 3, 2005·Histochemistry and Cell Biology·Koji Nishio, Akira Inoue

Epigenetic factors in aging and longevity

Sep 22, 2009·Pflügers Archiv : European journal of physiology·Silvia Gravina, Jan Vijg

Senescence in human intervertebral discs

Jun 15, 2006·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·S RobertsS M Eisenstein

Immunogenic cell death modalities and their impact on cancer treatment

Jan 16, 2009·Apoptosis : an International Journal on Programmed Cell Death·Oliver KeppGuido Kroemer

Modern principles of classification and development of nutrient media for culturing of human and animal cells

May 15, 2013·Bulletin of Experimental Biology and Medicine·V Yu TabakovV V Chestkov

Analysis of telomere length and telomerase activity in tree species of various life-spans, and with age in the bristlecone pine Pinus longaeva

Jul 22, 2005·Biogerontology·Barry E Flanary, Gunther Kletetschka

Telomerase activity in HeLa cervical carcinoma cell line proliferation

Sep 7, 2006·Biogerontology·Milena IvankovićIvica Rubelj

Low oxygen delays fibroblast senescence despite shorter telomeres

Oct 24, 2007·Biogerontology·Dean H BettsW Allan King

DmWRNexo is a 3'-5' exonuclease: phenotypic and biochemical characterization of mutants of the Drosophila orthologue of human WRN exonuclease

Oct 29, 2008·Biogerontology·Ivan BoubriakLynne S Cox

The in vitro kinetics of senescence of Fischer 344 rat embryo fibroblasts

Dec 31, 2008·Biogerontology·R G Faragher, Ian R Kill

Cell senescence: the future of ageing?

Dec 31, 2008·Biogerontology·Lynne S Cox

Cyclophosphamide induces premature senescence in normal human fibroblasts by activating MAP kinases

Feb 12, 2009·Biogerontology·Arivazhagan Palaniyappan

Activation of the immune response is a key feature of aging in mice

Mar 4, 2009·Biogerontology·Thore C BrinkJames Adjaye

Cell division and aging of the organism

Jul 7, 2011·Biogerontology·A Macieira-Coelho

Effects of serially passaged fibroblasts on dermal and epidermal morphogenesis in human skin equivalents

Mar 19, 2013·Biogerontology·David JansonAbdoelwaheb El Ghalbzouri

Senescent cells as a source of inflammatory factors for tumor progression

Apr 15, 2010·Cancer Metastasis Reviews·Albert R DavalosPierre-Yves Desprez

Assessment of organ culture for the conservation of human skin allografts

Apr 27, 2007·Cell and Tissue Banking·A HautierG Magalon

The use of comet assay in measuring DNA damage and repair efficiency in child, adult, and old age populations

Nov 27, 2007·Cell Biology and Toxicology·S M PiperakisM M Piperakis

Tpp1/Acd maintains genomic stability through a complex role in telomere protection

Jan 11, 2008·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·Tobias ElseDavid O Ferguson

Preferential reduction of the alpha-2-6-sialylation from cell surface N-glycans of human diploid fibroblastic cells by in vitro aging

Aug 10, 2006·Glycoconjugate Journal·Tomomi TadokoroKiyoshi Furukawa

Senescence, growth, and gerontology in the United States

Dec 5, 2012·Journal of the History of Biology·Hyung Wook Park

Women with high telomerase activity in luteinised granulosa cells have a higher pregnancy rate during in vitro fertilisation treatment

Jul 1, 2011·Journal of Assisted Reproduction and Genetics·Hong ChenDongzi Yang

The in vivo life span of normal and preneoplastic mouse mammary glands: a serial transplantation study. 1968

Aug 4, 2009·Journal of Mammary Gland Biology and Neoplasia·C W DanielL J Faulkin

Stem cell aging in the Drosophila ovary

Sep 1, 2005·Age·Morris WaskarJohn Tower

Twenty years of progress in biogerontology research

Dec 1, 2005·Age·Huber R Warner

Copper ability to induce premature senescence in human fibroblasts

Jun 23, 2011·Age·Liliana MatosHenrique Almeida

A role for c-Abl in cell senescence and spontaneous immortalization

Jul 14, 2012·Age·Man ZhangBaojie Li

Age-associated decreases in human DNA repair capacity: Implications for the skin

Apr 1, 1999·Age·I M HadshiewB A Gilchrest

Mechanism of immortalization

Apr 1, 1999·Age·K Hubbard, H L Ozer

Telomere shortening with aging in human esophageal mucosa

Jul 1, 1999·Age·K TakuboK Sasajima

Analysis and simulation of division- and label-structured population models : a new tool to analyze proliferation assays

Oct 23, 2012·Bulletin of Mathematical Biology·J HasenauerF Allgöwer

Telomeres: the time factor in essential hypertension

Feb 15, 2001·Current Hypertension Reports·A Aviv, W Zahorodny

Rethinking Alzheimer's disease: the role of age-related changes

Jul 10, 2007·Current Neurology and Neuroscience Reports·David A Drachman

MRGing chromatin dynamics and cellular senescence

Jan 31, 2008·Cell Biochemistry and Biophysics·Sandra N Garcia, Olivia M Pereira-Smith

Immunity and protection, the unfolding of a tale

Oct 6, 2007·Immunologic Research·Maurizio Zanetti

Bypassing cellular senescence by genetic screening tools

Jun 11, 2010·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·Mar Vergel, Amancio Carnero

Hematopoietic stem cell development, aging and functional failure

Apr 28, 2011·International Journal of Hematology·Jichun Chen

Reactive oxygen species and hematopoietic stem cell senescence

May 14, 2011·International Journal of Hematology·Lijian ShaoDaohong Zhou

Comparison of the effects of 40% oxygen and two atmospheric absolute air pressure conditions on stress-induced premature senescence of normal human diploid fibroblasts

May 10, 2008·Cell Stress & Chaperones·Sangnam OhSamyong Woo

Recovery from stress is a function of age and telomere length

May 21, 2008·Cell Stress & Chaperones·Graham M StrubShawn E Holt

Exploration of senescence-associated genes by differential display reverse transcription polymerase chain reaction: prosaposin as a novel senescence-associated gene

May 28, 2009·Archives of Pharmacal Research·Nam-Yi KimChuhee Lee

Epithelial-mesenchymal transition induced by senescent fibroblasts

Jun 28, 2011·Cancer Microenvironment : Official Journal of the International Cancer Microenvironment Society·Remi-Martin LabergePierre-Yves Desprez

Establishment of shrimp cell lines: perception and orientation

Sep 3, 2013·Indian Journal of Virology : an Official Organ of Indian Virological Society·P JayeshI S Bright Singh

Differences in vitro between cells derived from periodontal ligament and skin of Macaca irus

Jan 1, 1976·Archives of Oral Biology·Y MarmaryJ N Heersche

Activities of purine pathway enzymes in gouty human fibroblasts aged in vitro

Feb 1, 1977·Clinica Chimica Acta; International Journal of Clinical Chemistry·A J CliffordJ J Castles

Transdifferentiation and regeneration in vitro

Aug 1, 1982·Developmental Biology·V SchmidH Alder

Effects of cell density and cell growth alterations on cyclic nucleotide levels in cultured human diploid fibroblasts

Jun 1, 1978·Experimental Cell Research·H S AhnM H Makman

Plating efficiency measurements and the experimental control of ageing of adult human skin fibroblasts in vitro

Oct 1, 1978·Experimental Cell Research·D Couzin

Aging and sister chromatid exchange. II. The effect of the in vitro passage level of human fetal lung fibroblasts on baseline and mutagen-induced sister chromatid exchange frequencies

Sep 1, 1978·Experimental Cell Research·E L Schneider, R E Monticone

Establishment and characterization of an epithelial intestinal cell line from rat fetus

Feb 1, 1983·Experimental Cell Research·R NégrelG Ailhaud

Characterization of DNA polymerase alpha from untransformed and pSV3.neo-transformed human fibroblasts

Mar 1, 1993·The International Journal of Biochemistry·V K SrivastavaDavid L Busbee

Enhanced growth of smooth muscle cells from atherosclerotic rabbit aortas in culture

Jun 1, 1980·Atherosclerosis·K Pietilä, T Nikkari

Chlordiazepoxide and diazepam: absence of effects on the chromosomes of diploid human fibroblast cells

Jan 1, 1969·Mutation Research·G R Staiger

Normal DNA strand rejoining and absence of DNA crosslinking in progeroid and aging human cells

Nov 1, 1976·Mutation Research·M O BradleyK W Kohn

Human fibroblasts from cancer patients: lifespan and transformed phenotype in vitro and role of mesenchyme in vivo

Jun 1, 1988·Mutation Research·B AzzaroneA Macieira-Coelho

Differences in thymidine kinase-inducing ability of herpesvirus types 1 and 2

Dec 1, 1971·Virology·S P LowryW E Rawls

In vitro transdifferentiation of striated muscle to smooth muscle cells of a medusa

Mar 1, 1987·Cell Differentiation·C WeberV Schmid

A consequence of normal diploid cell mortality

Apr 1, 1973·Mechanisms of Ageing and Development·G Eaves

Primary causes of ageing: a brief review of some modern theories and concepts

Oct 1, 1973·Mechanisms of Ageing and Development·H P von Hahn

The position of aging studies

Mar 1, 1974·Mechanisms of Ageing and Development·A Comfort

DNA, RNA and protein synthesis in healing wounds in young and old mice

Sep 1, 1974·Mechanisms of Ageing and Development·P Holm-PedersenL E Folke

Aging changes in uptake of polysaccharides by human diploid cells in culture

Nov 1, 1974·Mechanisms of Ageing and Development·G D Press, J Pitha

Age-dependent micronuclear deterioration in Tetrahymena pyriformis, syngen 1

May 1, 1975·Mechanisms of Ageing and Development·R H Weindruch, F P Doerder

The lack of altered enzyme molecules in "senescent" mouse embryo fibroblasts in culture

May 1, 1975·Mechanisms of Ageing and Development·M Danot, H Gershon

Morphological changes in aging cell lines of Paramecium aurella. I. Alterations in the cytoplasm

Mar 1, 1976·Mechanisms of Ageing and Development·V Sundararaman, D J Cummings

Decreased proteolysis and increased amino acid efflux in aging human fibroblasts

May 1, 1976·Mechanisms of Ageing and Development·S GoldsteinR A Cordeiro

A lack of correlation between decline in growth capacity and nuclear RNA synthesising activity in ageing human embryo cells in culture

Jul 1, 1976·Mechanisms of Ageing and Development·B T Hill

Morphological changes in aging cell lines of Paramecium aurelia. II. Macronuclear alterations

Sep 1, 1976·Mechanisms of Ageing and Development·V Sundararaman, D J Cummings

Development of the aging cell surface: a freeze-fracture analysis of gap junctions between human embryo fibroblasts aging in culture. A brief note

Sep 1, 1976·Mechanisms of Ageing and Development·R O Kelley

Altered protein metabolism in arrested populations of aging human diploid fibroblasts

Jan 1, 1976·Mechanisms of Ageing and Development·R T Dell'Orco, P L Guthrie

Ribosome editing and the error catastrophe hypothesis of cellular aging

Mar 1, 1977·Mechanisms of Ageing and Development·J R Menninger

Macromolecular synthesis in human fibroblasts at 37 degrees and 42 degrees C during aging in vitro

May 1, 1977·Mechanisms of Ageing and Development·S Goldstein, G W Csullog

Somatic cell hybrids derived from terminally differentiated rhesus cells and established mouse cell lines

Jul 1, 1977·Mechanisms of Ageing and Development·F HuD J Teramura

The dynamics of repetitive asymmetric cell division

Sep 1, 1977·Mechanisms of Ageing and Development·H R Hirsch

Comparison by autoradiography of macromolecular biosynthesis in "young" and "old" human diploid fibroblast cultures. A brief note

Sep 1, 1977·Mechanisms of Ageing and Development·S RazinL Hayflick

The waste-product theory of aging: waste dilution by cell division

Jul 1, 1978·Mechanisms of Ageing and Development·H R Hirsch

Evidence that transcription changes in ageing cultures are terminal events occurring after the expression of a reduced replicative potential

Aug 1, 1978·Mechanisms of Ageing and Development·B T HillS Whatley

Development of the aging cell surface: concanavalin A-mediated intercellular binding and the distribution of binding sites with progressive subcultivation of human embryo fibroblasts

Sep 1, 1978·Mechanisms of Ageing and Development·R O KelleyK G Vogel

Ageing of chick embryo fibroblasts in vitro. II. Relationship between cell proliferation and increased multinuclear cells

Oct 1, 1978·Mechanisms of Ageing and Development·K Kaji, M Matsuo

Relationship between glucose phosphorylating activities and erythrocyte age

Oct 1, 1978·Mechanisms of Ageing and Development·G FornainiV Stocchi

Age-related decline in the synthesis of glycosaminoglycans by cultured human fibroblasts (WI-38)

Oct 1, 1978·Mechanisms of Ageing and Development·D O Schachtschabel, J Wever

Unscheduled dna synthesis in confluent and mitotically arrested populations of aging human diploid fibroblasts

Oct 1, 1978·Mechanisms of Ageing and Development·R T Dell'Orco, W L Whittle

Nucleolar changes in senescing WI-38 cells

Dec 1, 1978·Mechanisms of Ageing and Development·P M Bemiller, L H Lee

Correlation between DNA repair of embryonic fibroblasts and different life span of 3 inbred mouse strains

Aug 1, 1978·Aktuelle Gerontologie·V Paffenholz

Nuclear area changes in senescing human diploid fibroblasts

Jun 1, 1978·Mechanisms of Ageing and Development·S C LeeA J Pappelis

Age-related cell surface changes in human diploid fibroblasts revealed by lectin-mediated red blood cell adsorption assay: a lectin survey

Nov 1, 1979·Mechanisms of Ageing and Development·S Aizawa, F Kurimoto

Fine structure of IMR-90 cells in culture as examined by scanning and transmission electron microscopy

Jul 1, 1979·Mechanisms of Ageing and Development·J E Johnson

Effect of cell density and senescence of WI-38 cells on cytochemically demonstrable phosphatases

Sep 1, 1979·Mechanisms of Ageing and Development·A VorbrodtV J Cristofalo

Strict relationship between dialyzed serum concentration and cellular life span in vitro

Oct 1, 1979·Mechanisms of Ageing and Development·T Ohno

On the duration of mitotic stages in senescing human fibroblasts in culture

Oct 1, 1979·Mechanisms of Ageing and Development·J E Sisken, S V Bonner

Evidence for an increase in presumed somatic mutation during the ageing of human cells in culture

Apr 1, 1979·Mechanisms of Ageing and Development·S J Fulder

Proliferative homeostasis and its age-related aberrations

Mar 1, 1979·Mechanisms of Ageing and Development·G M Martin

Progress in cytogerontology

Mar 1, 1979·Mechanisms of Ageing and Development·L Hayflick

Proliferative capacity of erythropoietic stem cell lines and aging: an overview

Mar 1, 1979·Mechanisms of Ageing and Development·D E Harrison

The relevance of growth control (chalones) to the aging process

Mar 1, 1979·Mechanisms of Ageing and Development·J C Houck

Hydrocortisone: a specific modulator of in vitro cell proliferation and aging

Mar 1, 1979·Mechanisms of Ageing and Development·B A Rosner, V J Cristofalo

Cellular replication and aging

Feb 1, 1979·Mechanisms of Ageing and Development·E L SchneiderG Bynum

T-cell division and aging

Jan 1, 1979·Mechanisms of Ageing and Development·H GershonC Abraham

An overview of immune aging

Jan 1, 1979·Mechanisms of Ageing and Development·M M Kay

Phase-space description of the cell cycle: application to noncycling, senescent, and transformed cells

Jan 1, 1980·Mechanisms of Ageing and Development·H R Hirsch

Commitment theory of cellular aging: possibility of an immortal diploid cell strain

Jan 1, 1980·Mechanisms of Ageing and Development·H R Hirsch

The sensitivity to hyperbaric oxygen of human diploid fibroblasts during ageing in vitro

Jan 1, 1980·Mechanisms of Ageing and Development·S Honda, M Matsuo

A low-density inoculation method for the serial subcultivation of human diploid fibroblasts: an efficient model system for the study of cellular ageing

Jul 1, 1980·Mechanisms of Ageing and Development·K Kaji, M Matsuo

RNA and protein synthesis in cultured human fibroblasts derived from donors of various ages

Jul 1, 1980·Mechanisms of Ageing and Development·J J ChenH Weissbach

Mechanisms of development and aging

Mar 1, 1980·Mechanisms of Ageing and Development·B E Wright, P F Davison

Variation in cytoskeletal assembly during spreading of progressively subcultivated human embryo fibroblasts (IMR-90)

Jun 1, 1980·Mechanisms of Ageing and Development·R O KelleyC B Taylor

Selective elimination of proliferating cells in human diploid cell cultures by treatment with BrdU, 33258 Hoechst and visible light

Feb 1, 1980·Mechanisms of Ageing and Development·G C Burmer, T H Norwood

Ageing of human glial cells in culture: increase in the fraction of non-dividers as demonstrated by a minicloning technique

Feb 1, 1980·Mechanisms of Ageing and Development·E BlomquistJ Ponten

Fixation of cellular aging processes by SV40 virus transformation

Feb 1, 1980·Mechanisms of Ageing and Development·H KajiK D Lamon

Recent advances in the cell biology of aging

Sep 1, 1980·Mechanisms of Ageing and Development·L Hayflick

Spontaneous structural changes in DNA during fibroblast aging and the establishment process in vitro

Sep 1, 1980·Mechanisms of Ageing and Development·C Icard, R Beaupain

Variations in the stromal cell population of human bone marrow during aging

Jan 1, 1981·Mechanisms of Ageing and Development·T Mets, G Verdonk

Senescence in vitro and ionising radiations--the human diploid fibroblast model

Jan 1, 1981·Mechanisms of Ageing and Development·A F Stevenson, T Cremer

Loss of organized fibronectin matrix from the surface of aging diploid fibroblasts (IMR-90)

Jan 1, 1981·Mechanisms of Ageing and Development·K G VogelC Stewart

Properties of DNA polymerases from young and ageing human fibroblasts

Jan 1, 1981·Mechanisms of Ageing and Development·V Murray

Age-related changes in the distribution pattern of glycosaminoglycans synthesized by cultured human diploid fibroblasts (WI-38)

May 1, 1981·Mechanisms of Ageing and Development·G SlukeJ Wever

In vitro aging of human bone marrow derived stromal cells

May 1, 1981·Mechanisms of Ageing and Development·T Mets, G Verdonk

Hydrocortisone effects on nucleic acid and nuclear protein content and protein metabolism in aging WI-38 cells

Nov 1, 1981·Mechanisms of Ageing and Development·P A DochertyR B Mitchell

Evidence for an increased level of DNA damage in high doubling level human diploid cells culture

Feb 1, 1981·Mechanisms of Ageing and Development·R T Dell'Orco, W L Whittle

Superoxide dismutase in Didymium iridis: characterization and changes in activity during senescence and sporulation

Oct 1, 1981·Mechanisms of Ageing and Development·T LottJ Clark

Effects of in vitro aging and cell growth on the viability and recovery of human diploid fibroblasts, TIG-1, after freezing and thawing

Jun 1, 1981·Mechanisms of Ageing and Development·H Kondo, K Yamamoto

Ageing and the fusion sensitivity potential of human cells in culture: relation to tissue origin, donor age, and in vitro culture level and condition

Jul 1, 1981·Mechanisms of Ageing and Development·D Röhme

Modeling cellular systems and aging processes: I. Mathematics of cell system models-a review

Sep 1, 1981·Mechanisms of Ageing and Development·M Witten

Senescence of aortic endothelial cells in vitro: influence of culture conditions and preliminary characterization of the senescent phenotype

Jan 1, 1982·Mechanisms of Ageing and Development·L K Johnson, J P Longenecker

Reactivation of DNA synthesis in aging diploid human skin fibroblasts by fusion with mouse L karyoplasts cytoplasts and whole L cells

Jan 1, 1982·Mechanisms of Ageing and Development·E G NetteD W King

Age-dependent decline of T-cell cloning potential in mice

Apr 1, 1982·Mechanisms of Ageing and Development·N FabrisE Mocchegiani

Optimum conditions for growth and longevity of chick embryo fibroblasts in culture

May 1, 1982·Mechanisms of Ageing and Development·S I Rattan, J H Buchanan

In vitro characterization of response to stimulus (wounding) with regard to ageing in human skin fibroblasts

May 1, 1982·Mechanisms of Ageing and Development·A L Muggleton-HarrisR L Burghoff

Increase of cell surface hyaluronic acid during aging in human liver cells

Jul 1, 1982·Mechanisms of Ageing and Development·B BernardA Guillouzo

The role of limited cell replicative capacity in pathological age change. A review

Jul 1, 1982·Mechanisms of Ageing and Development·J Walton

Increased lability of triosephosphate isomerase in progeria and Werner's syndrome fibroblasts

Oct 1, 1982·Mechanisms of Ageing and Development·T O TollefsbolR W Gracy

Involvement of ribonucleotide reductase activity in the senescence of normal human diploid fibroblasts

Oct 1, 1982·Mechanisms of Ageing and Development·J E Dick, J A Wright

Depletion of reserve in the hemopoietic system: I. Self-replication by stromal cells related to chronologic age

Oct 1, 1982·Mechanisms of Ageing and Development·N S Wolf, R K Arora

Encephalomyocarditis virus as a probe of errors in macromolecular synthesis in aging mice

Oct 1, 1982·Mechanisms of Ageing and Development·P S Rabinovitch, G M Martin

Cholesterol and cholesteryl ester concentration in different size classes of cultured human fibroblasts: effect of in vitro aging

Oct 1, 1982·Mechanisms of Ageing and Development·M F EthierR H Saunders

A long-lived human diploid fibroblast line for cellular aging studies: applications in cell hybridization

Nov 1, 1982·Mechanisms of Ageing and Development·G S DuthuJ R Smith

Similarity between in vitro and in vivo cellular aging

May 1, 1983·Mechanisms of Ageing and Development·T MetsG Verdonk

Stromal DNA synthesis is stimulated by young, but not serially aged, mouse mammary epithelium

Nov 1, 1983·Mechanisms of Ageing and Development·J J Berger, C W Daniel

Effects of various steroids on in vitro lifespan and cell growth of human fetal lung fibroblasts (WI-38)

Mar 1, 1983·Mechanisms of Ageing and Development·H KondoT Noumura

Observations on the senescence of cells derived from articular cartilage

Jun 1, 1983·Mechanisms of Ageing and Development·C H Evans, H I Georgescu

Intracellular determinants of cell aging

Dec 1, 1984·Mechanisms of Ageing and Development·L Hayflick

DNA repair deficiencies and cellular senescence are unrelated in xeroderma pigmentosum cell lines

Oct 15, 1984·Mechanisms of Ageing and Development·J E Cleaver

Loss of responsiveness in senescent human TIG-1 cells to the DNA synthesis-inducing effect of various growth factors

Oct 15, 1984·Mechanisms of Ageing and Development·Y TsujiK Nishikawa

Fibronectin distribution on the surfaces of young and old human fibroblasts

Oct 15, 1984·Mechanisms of Ageing and Development·G F Edick, A J Millis

Correlation of DNA repair synthesis with ageing in mice, evidenced by quantitative autoradiography

Aug 1, 1984·Mechanisms of Ageing and Development·C KempfJ Kempf

Alteration of enzymes in ageing human fibroblasts in culture. I. Conditions for the appearance of an alteration in glucose 6-phosphate dehydrogenase

Apr 1, 1984·Mechanisms of Ageing and Development·A HoubenJ Remacle

Alteration of enzymes in ageing human fibroblasts in culture. II. Conditions for the reversibility and the mechanism of the alteration of glucose 6-phosphate dehydrogenase

Apr 1, 1984·Mechanisms of Ageing and Development·A HoubenJ Remacle

Human diploid fibroblasts with alterations in ribonucleotide reductase activity, deoxyribonucleotide pools and in vitro lifespan

Jul 1, 1984·Mechanisms of Ageing and Development·J E Dick, J A Wright

Effect of donor age on long-term culture of bone marrow in vitro

Jan 1, 1984·Mechanisms of Ageing and Development·D A Lipschitz, Kodetthoor B Udupa

Effect of lead on fibroblasts taken from an 84-year-old donor

May 13, 1985·Mechanisms of Ageing and Development·P M Bemiller, S C Reeder

Alteration of enzymes in ageing human fibroblasts in culture. III. Modification of superoxide dismutase as an environmental and reversible process

Jan 1, 1985·Mechanisms of Ageing and Development·M SomvilleJ Remacle

Reduction of filamin in late passage human diploid fibroblasts (IMR-90)

Apr 1, 1985·Mechanisms of Ageing and Development·R O KelleyL F Marek

Neurotropin increases in vitro life span of human fibroblasts

Jul 1, 1986·Mechanisms of Ageing and Development·Y OkadaT Aoyama

Growth factor responsiveness declines during adulthood for human skin-derived cells

Jul 1, 1986·Mechanisms of Ageing and Development·B M Stanulis-Praeger, B A Gilchrest

Changes in the higher order organization of DNA during aging of human fibroblast-like cells

Jul 1, 1986·Mechanisms of Ageing and Development·R T Dell'OrcoA Macieira-Coelho

Induction of heat shock proteins in young and senescent human diploid fibroblasts

Oct 1, 1986·Mechanisms of Ageing and Development·Y TsujiT Ide

In vitro senescence of Syrian hamster mesenchymal cells of fetal to aged adult origin. Inverse relationship between in vivo donor age and in vitro proliferative capacity

Apr 1, 1986·Mechanisms of Ageing and Development·S A BruceP O Ts'o

Age-related changes in rabbit articular chondrocytes

Jan 1, 1986·Mechanisms of Ageing and Development·J DominiceM Adolphe

Filopodia number increases with age and quiescence in populations of normal WI-38 cells, and is correlated with drug-induced changes in proliferation in both normal and transformed populations

Feb 1, 1986·Mechanisms of Ageing and Development·B M Stanulis-Praeger

An altered response in the induction of cell membrane (Na + K)ATPase by thyroid hormone is characteristic of senescence in cultured human fibroblasts

Feb 1, 1986·Mechanisms of Ageing and Development·D L GuernseyD Zmolek

Events blocked in prereplicative phase in senescent human diploid cells, TIG-1, following serum stimulation

Dec 1, 1986·Mechanisms of Ageing and Development·F KiharaT Ide

Mechanisms of age-related decline in antigen-specific T cell proliferative response: IL-2 receptor expression and recombinant IL-2 induced proliferative response of purified Tac-positive T cells

Nov 14, 1986·Mechanisms of Ageing and Development·S NegoroS Kishimoto

Comparison of haemopoiesis in young and old mice

Mar 1, 1986·Mechanisms of Ageing and Development·R SchofieldN G Testa

Failure in S6 protein phosphorylation by serum stimulation of senescent human diploid fibroblasts, TIG-1

Nov 28, 1986·Mechanisms of Ageing and Development·F KiharaT Ide

Culture media variation as related to in vitro aging of human fibroblasts: I. Effects on population doubling, nuclear volume and nuclear morphology

Nov 28, 1986·Mechanisms of Ageing and Development·A B Mukherjee, M E Weinstein

The waste-product theory of aging: cell division rate as a function of waste volume

Sep 1, 1986·Mechanisms of Ageing and Development·H R Hirsch

In vitro replication potential of serially passaged mammary parenchyma from mice with different reproductive histories

Jul 1, 1987·Mechanisms of Ageing and Development·N ChoogkittawornW Jones

Comparison of proto oncogene expression in seven primate fibroblast cultures

Jul 1, 1987·Mechanisms of Ageing and Development·K Nakamura, R W Hart

Lack of recovery from oxygen-induced damage to colony formation and DNA synthesis in senescent human diploid fibroblasts

Sep 14, 1987·Mechanisms of Ageing and Development·S Honda, M Matsuo

Age-correlated DNA damage in human muscle tissue

Nov 1, 1987·Mechanisms of Ageing and Development·R K ZahnV Pondeljak

Evidence for a universal process underlying clonal attenuation

May 1, 1987·Mechanisms of Ageing and Development·J C Angello, J Prothero

Cellular senescence revisited: a review

Mar 1, 1987·Mechanisms of Ageing and Development·B M Stanulis-Praeger

Cellular aging (the Hayflick limit) and species longevity: a unification model based on clonal succession

Mar 1, 1987·Mechanisms of Ageing and Development·D A Juckett

Culture media variation as related to in vitro aging of human fibroblasts: II. Effects on nucleolar number/cell, volume/nucleolus and total nucleolar volume/cell

Mar 1, 1988·Mechanisms of Ageing and Development·M E Weinstein, A B Mukherjee

Effects of serum from human subjects of different ages on migration in vitro of human fibroblasts

Jan 1, 1989·Mechanisms of Ageing and Development·H KondoY Yonezawa

Independent evidence for a commitment model of clonal attenuation

Sep 1, 1989·Mechanisms of Ageing and Development·J C Angello, J Prothero

Growth properties and in vitro life span of Alzheimer disease and Down syndrome fibroblasts. A blind study

Mar 31, 1990·Mechanisms of Ageing and Development·G CarmelietJ J Cassiman

Changes in frequency and localization of human X- and Y-chromatin bodies at interphase during in vitro cellular aging

Mar 31, 1990·Mechanisms of Ageing and Development·A B Mukherjee, K C Wallace

Appearance of the terminal senescent cell population in human diploid fibroblasts analyzed by flow cytometry

Feb 15, 1990·Mechanisms of Ageing and Development·M YamamotoK Yamamoto

A new method for testing cell ageing using two mitochondria specific fluorescent probes

Mar 15, 1990·Mechanisms of Ageing and Development·P LepratR Julien

Tumor necrosis factor reduces lifespan of human endothelial cells in vitro

Sep 1, 1990·Mechanisms of Ageing and Development·Y ShimadaM Fukuda

Importance of a threshold for error accumulation in cell degenerative processes. I. Modulation of the threshold in a model of free radical-induced cell degeneration

Jan 1, 1990·Mechanisms of Ageing and Development·C MichielsJ Remacle

Alteration of enzymes in ageing human fibroblasts in culture. V. Mechanisms of glutathione peroxidase modification

Apr 1, 1991·Mechanisms of Ageing and Development·E Pigeolet, J Remacle

Age-related differences in promoter-induced extension of in vitro proliferative life span of Syrian hamster fibroblasts

Oct 1, 1991·Mechanisms of Ageing and Development·S F Deamond, S A Bruce

Comparison of rates of neuronal development and survival in human and rat cerebral cortical cell cultures

Oct 1, 1991·Mechanisms of Ageing and Development·M P Mattson, B Rychlik

The effect of in vitro aging on human lung fibroblast beta-adrenergic receptor density, coupling and response

May 1, 1992·Mechanisms of Ageing and Development·S A KilfeatherK O'Malley

Differential gene expression between young and senescent, quiescent WI-38 cells

Sep 1, 1992·Mechanisms of Ageing and Development·D L DoggettV J Cristofalo

The effect of donor age on human fibroblast beta-adrenergic receptor response and agonist-induced desensitization

Feb 1, 1992·Mechanisms of Ageing and Development·D ConlonS A Kilfeather

Epidermal growth factor suppresses in vitro senescence in the ability of human umbilical vein endothelial cells to proliferate, but not in the ability to produce prostacyclin

Jan 1, 1992·Mechanisms of Ageing and Development·N Hasegawa, K Yamamoto

Aging as a multi-step process characterized by a lowering of entropy production leading the cell to a sequence of defined stages. II. Testing some predictions on aging human fibroblasts in culture

Aug 1, 1992·Mechanisms of Ageing and Development·Olivier ToussaintJ Remacle

Gene expression and aging

Jan 1, 1993·Mechanisms of Ageing and Development·M K ThakurY Natori

A mathematical model of the effect of aging on bone marrow cells colonizing the thymus

Feb 1, 1993·Mechanisms of Ageing and Development·R MehrZ Agur

The in vitro senescence of human T lymphocytes: failure to divide is not associated with a loss of cytolytic activity or memory T cell phenotype

Feb 1, 1993·Mechanisms of Ageing and Development·N L PerilloR B Effros

Chromosomal analysis in young vs. senescent human fibroblasts by fluorescence in situ hybridization: a selection hypothesis

Apr 21, 1995·Mechanisms of Ageing and Development·A B MukherjeeE Schmitt

A theory that may explain the Hayflick limit--a means to delete one copy of a repeating sequence during each cell cycle in certain human cells such as fibroblasts

Sep 1, 1994·Mechanisms of Ageing and Development·P NaveilhanD Wion

Human arterial smooth muscle cell strains derived from patients with moyamoya disease: changes in biological characteristics and proliferative response during cellular aging in vitro

Jul 1, 1994·Mechanisms of Ageing and Development·N FukaiK Yamamoto

Relevance of oxidative stress to the limited replicative capacity of cultured human diploid cells: the limit of cumulative population doublings increases under low concentrations of oxygen and decreases in response to aminotriazole

Jul 14, 1995·Mechanisms of Ageing and Development·H YuanM Matsuo

Enhanced expression of cyclin D1 in senescent human fibroblasts

Jul 14, 1995·Mechanisms of Ageing and Development·J FukamiT Ide

In vitro senescence enhances IL-6 production in human gingival fibroblasts induced by lipopolysaccharide from Campylobacter rectus

May 24, 1996·Mechanisms of Ageing and Development·N OguraY Abiko

Insulin exposure controls the rate of mammalian aging

Jul 5, 1996·Mechanisms of Ageing and Development·T Parr

Enhanced cell proliferation and biosynthesis mediate improved wound repair in refed, caloric-restricted mice

Jul 31, 1996·Mechanisms of Ageing and Development·M J ReedN S Wolf

DNA status in brain and heart as prominent co-determinant for life span? Assessing the different degrees of DNA damage, damage susceptibility, and repair capability in different organs of young and old mice

Aug 15, 1996·Mechanisms of Ageing and Development·R K ZahnG Zahn-Daimler

Evidence for cellular aging in long-term confluent cultures: heritable impairment of proliferation, accumulation of age pigments and their loss in neoplastic transformation

Aug 29, 1996·Mechanisms of Ageing and Development·M Chow, H Rubin

Studies of mammalian ribonucleotide reductase activity in intact permeabilized cells: a genetic approach

Jan 1, 1980·Advances in Enzyme Regulation·J A WrightJ E Dick

Study of the population dynamics of human diploid cell strain WI-38. III. Serial cultivation of the cells

Apr 1, 1974·Journal of Biological Standardization·D Slonim

Simple and rapid evaluation of serum for cell culture

Jan 1, 1975·Journal of Biological Standardization·D Pye

Molecular aspects of aging

Jan 1, 1985·Molecular Aspects of Medicine·A K Roy, B Chatterjee

Ageing--a biological perspective

Jan 1, 1995·Molecular Aspects of Medicine·S I Rattan

Cellular and molecular advances in elucidating p53 function

Aug 1, 1992·Mutation Research·Jerry W ShayWoodring E Wright

International Commission for Protection Against Environmental Mutagens and Carcinogens. Oxidative DNA damage--the effects of certain genotoxic and operationally non-genotoxic carcinogens

Feb 1, 1994·Mutation Research·D B ClaysonF Iverson

Clonal fibroblastic cell lines established from a heavily exposed atomic bomb survivor

Apr 1, 1993·Mutation Research·T HondaO Kusumi

A hypodiploid karyotype found in immortal human cells selected from a wide spectrum of posttransformation chromosomal complements

Jul 1, 1989·Cancer Genetics and Cytogenetics·T Naiman, D Canaani

Appearance of isochromosome 18q can be associated with in vitro immortalization of human T lymphocytes

May 1, 1995·Cancer Genetics and Cytogenetics·K KaltoftK Thestrup-Pedersen

Human fibroblast strains showing increased sensitivity or resistance to ethidium bromide

Sep 1, 1982·Mutation Research·R S Gupta, S Goldstein

Constancy of ribosomal RNA genes during aging of mouse heart cells and during serial passage of WI-38 cells

Jul 1, 1984·Archives of Gerontology and Geriatrics·C R PetersonJ W Gaubatz

Influence of dietary protein restriction on cell number, cell size and growth of mouse organs during the course of aging

Oct 1, 1986·Archives of Gerontology and Geriatrics·H E Enesco, J Samborsky

Establishment by SV40 transformation and characteristics of a cell line of xeroderma pigmentosum belonging to complementation group F

Feb 1, 1983·Mutation Research·T Yagi, H Takebe

Evidence that DNA excision-repair in xeroderma pigmentosum group A is limited but biologically significant

Jun 1, 1983·Mutation Research·D R Hull, G J Kantor

The rate of removal of pyrimidine dimers in quiescent cultures of normal human and xeroderma pigmentosum cells

Jul 1, 1984·Mutation Research·G J Kantor, D R Hull

DNA repair in cultured mouse cells of increasing population doubling level

Jul 1, 1984·Mutation Research·M La Belle, S Linn

Establishment of cell lines derived from ataxia telangiectasia and xeroderma pigmentosum patients with high radiation sensitivity

Sep 1, 1986·Mutation Research·T HashimotoJ Furuyama

A further definition of characteristics of DNA-excision repair in xeroderma pigmentosum complementation group A strains

Jul 1, 1986·Mutation Research·G J Kantor, A N Player

The endogenous nuclease sensitivity of repaired DNA in human fibroblasts

Sep 1, 1987·Mutation Research·A N Player, G J Kantor

Cloning the gene for Werner syndrome: a disease with many symptoms of premature aging

Aug 1, 1996·Trends in Genetics : TIG·D B Lombard, L Guarente

Neuron numbers in locus coeruleus do not change with age in Fisher 344 rat

Jan 1, 1981·Neurobiology of Aging·G Goldman, P D Coleman

New models for new perspectives in the biology of senescence

Nov 1, 1991·Neurobiology of Aging·C E Finch

T cell cultures and the Hayflick limit

Jan 1, 1984·Human Immunology·R B Effros, R L Walford

Cytotoxicity of linoleic acid peroxide, malondialdehyde and 4-hydroxynonenal towards human fibroblasts

Feb 1, 1991·Toxicology·C Michiels, J Remacle

Insulin stimulates cell growth of a new strain of differentiated rat thyroid cells

Nov 1, 1987·Molecular and Cellular Endocrinology·M L BrandiR Toccafondi

Ageing of the spinal ganglion neurons in the rat: a radioautographic study following injection of [3H]lysine

Jul 1, 1980·Neuroscience Letters·P van den Bosch de Aguilar, J Vanneste

Cellular senescence and atherosclerosis

Jun 1, 1984·Medical Hypotheses·B Johansson

Aging: a non-regulated process

Apr 1, 1988·Medical Hypotheses·J Segal

Stem cell depletion: an explanation of the late effects of cytotoxins

Jan 1, 1977·International Journal of Radiation Oncology, Biology, Physics·S Hellman, L Botnick

Vectors for the direct selection of cDNA clones corresponding to mammalian cell mRNA of low abundance

Jan 1, 1985·Gene·J KowalskiD T Denhardt

Testing garlic for possible anti-ageing effects on long-term growth characteristics, morphology and macromolecular synthesis of human fibroblasts in culture

Jul 8, 1994·Journal of Ethnopharmacology·L SvendsenB F Clark

Macromolecular aspects of ageing

Aug 1, 1968·Experimental Gerontology·Z Deyl

Effect of collagenase on the behaviour of cells from young and old donors in culture

Aug 1, 1968·Experimental Gerontology·M SoukupováZ Hrůza

The division potential of cells in continuous growth as compared to cells subcultivated after maintenance in stationary phase

Mar 1, 1968·Experimental Gerontology·R J HayB L Strehler

Aging under glass

Dec 1, 1970·Experimental Gerontology·L Hayflick

The regulation of protein synthesis in the ageing cell

Dec 1, 1970·Experimental Gerontology·H P von Hahn

Age-dependent regulation of mammalian DNA synthesis and cell division in vivo by glucocorticoids

Feb 1, 1974·Experimental Gerontology·G S Roth, R C Adelman

Microsomal mixed-function oxidase activity and senescence--II. In vivo and in vitro hepatic drug metabolism in rats of different ages following partial hepatectomy

Jan 1, 1976·Experimental Gerontology·M B BairdL V Pacilio

The small intestine in old mice: growth, alkaline phosphatase and disaccharidase activities, and deposition of amyloid

Jan 1, 1977·Experimental Gerontology·F Moog

Increased levels of euploidy as a strategy against rapid ageing in diploid mammalian systems: an hypothesis

Jan 1, 1977·Experimental Gerontology·P B Gahan

Short communication lysosomal and mitochondrial heat labile enzymes in Werner's syndrome fibroblasts

Jan 1, 1980·Experimental Gerontology·A HoubenJ Remacle

Continued in vitro growth of fibroblast-like cells (RBCF-1) derived from the caudal fin of the fish, Carassius auratus

Jan 1, 1980·Experimental Gerontology·A ShimaN Egami

Change in activity of fibroblast mitotic inhibitor from mouse embryo cells aging in vitro and undergoing spontaneous transformation

Jan 1, 1980·Experimental Gerontology·C Due, P Ebbesen

Development of the aging cell surface: structural patterns of gap junction assembly between metabolic mutants and progressively subcultivated human diploid fibroblasts (IMR-90)

Jan 1, 1980·Experimental Gerontology·R O Kelley, B D Perdue

Ganglioside changes during cell aging in human diploid fibroblast TIG-1

Jan 1, 1982·Experimental Gerontology·T Ohsawa, Y Nagai

Influence of drugs on macromolecular synthesis during cell synchronization

Jan 1, 1982·Experimental Gerontology·J L ChigerH Kaji

Age-related ultrastructural changes in human embryonic lung fibroblasts

Jan 1, 1983·Experimental Gerontology·A M BoakP J Quinn

Tissue-specificity of reactivity to concanavalin-A of human cells in culture

Jan 1, 1983·Experimental Gerontology·S Ban, S Iida

Theories of biological aging

Jan 1, 1985·Experimental Gerontology·L Hayflick

Genetic instability as the primary cause of human aging

Jan 1, 1986·Experimental Gerontology·B L Strehler

Sir Frank MacFarlane Burnet 1899-1985

Jan 1, 1986·Experimental Gerontology·T Makinodan

Changes in activity and amount of active elongation factor 1 alpha in aging and immortal human fibroblast cultures

Jan 1, 1986·Experimental Gerontology·J CavalliusB F Clark

Cell aging in vitro: a historical perspective

Jan 1, 1987·Experimental Gerontology·J A Witkowksi

Alteration of the microtubule organization in aging WI-38 fibroblasts. A comparative study with embryonic hamster lung fibroblasts

Jan 1, 1987·Experimental Gerontology·M Raes, J Remacle

Neonatal T cells as a model system to study the possible in vitro senescence of lymphocytes

Jan 1, 1987·Experimental Gerontology·R B Effros, R L Walford

Comparison of major cytoskeletons among normal human fibroblasts, immortal human fibroblasts transformed by exposure to Co-60 gamma rays, and the latter cells made tumorigenic by treatment with Harvey murine sarcoma virus

Jan 1, 1987·Experimental Gerontology·M NambaT Kimoto

Cellular biomarkers of aging

Jan 1, 1988·Experimental Gerontology·V J Cristofalo

Relationships between the cellular glutathione level and in vitro life span of human diploid fibroblasts

Jan 1, 1988·Experimental Gerontology·S Honda, M Matsuo

Effect of procaine on cultivated human WI-38 fibroblasts

Jan 1, 1988·Experimental Gerontology·E PigeoletJ Remacle

Human T lymphocytes possess a limited in vitro life span

Jan 1, 1989·Experimental Gerontology·N L PerilloR B Effros

The waste-product theory of aging: transformation to unlimited growth in cell cultures

Jan 1, 1989·Experimental Gerontology·H R HirschM Witten

Decreased accuracy of protein synthesis in extracts from aging human diploid fibroblasts

Jan 1, 1989·Experimental Gerontology·M C Luce, C L Bunn

Age and cell density dependent changes of gangliosides in human diploid fibroblasts

Jan 1, 1989·Experimental Gerontology·T Ohsawa

Antecedents of cell aging research

Jan 1, 1989·Experimental Gerontology·L Hayflick

Interferon and the epidermis: implications for cellular senescence

Jan 1, 1989·Experimental Gerontology·M PeacockeB A Gilchrest

Levels of DNA methylation in diploid and SV40 transformed human fibroblasts

Jan 1, 1989·Experimental Gerontology·T MatsumuraR Holliday

Cloning and molecular characterization of a cDNA clone to statin, a protein specifically expressed in nonproliferating quiescent and senescent fibroblasts

Jan 1, 1989·Experimental Gerontology·E WangT Nakamura

Increase in abundance of a transcript hybridizing to elongation factor I alpha during cellular senescence and quiescence

Jan 1, 1989·Experimental Gerontology·T GiordanoD N Foster

Growth-factor-inducible gene expression in senescent human fibroblasts

Jan 1, 1989·Experimental Gerontology·T Seshadri, J Campisi

Polyamine metabolism and cell-cycle-dependent gene expression in IMR-90 human diploid fibroblasts during senescence in culture

Jan 1, 1989·Experimental Gerontology·K Y ChenA Y Liu

Collagenase production by early and late passage cultures of human fibroblasts

Jan 1, 1989·Experimental Gerontology·A J MillisV Diemer

Longevity and age-related pathology of LVG outbred golden Syrian hamsters (Mesocricetus auratus)

Jan 1, 1990·Experimental Gerontology·S F DeamondS A Bruce

Long-term growth of diploid human fibroblasts in low serum media

Jan 1, 1990·Experimental Gerontology·C Wistrom, B Villeponteau

Isozyme polymorphisms in human diploid cell strains for research on cellular aging

Jan 1, 1991·Experimental Gerontology·Y TasakiK Yamamoto

Ultrastructure of dermal fibroblasts during development and aging: relationship to in vitro senescence of dermal fibroblasts

Jan 1, 1991·Experimental Gerontology·S A Bruce

Longitudinal study of in vivo wound repair and in vitro cellular senescence of dermal fibroblasts

Jan 1, 1991·Experimental Gerontology·S A Bruce, S F Deamond

Enhanced frequency of spontaneous B cell lines from Epstein-Barr virus (EBV) seropositive donors 80 years and older

Jan 1, 1991·Experimental Gerontology·S R Rangan, P Armatis

The waste-product theory of aging: simulation of metabolic waste production

Jan 1, 1991·Experimental Gerontology·H R Hirsch, M Witten

Re-expression of senescent markers in deinduced reversibly immortalized cells

Sep 1, 1992·Experimental Gerontology·Jerry W ShayWoodring E Wright

Characterization of the absence of an unique DNA-binding protein in senescent but not in their young growing and nongrowing counterparts provides the means to mark the final stage of the cellular aging process

Sep 1, 1992·Experimental Gerontology·E Wang

Molecular genetic studies of cellular senescence

Sep 1, 1992·Experimental Gerontology·Olivia M Pereira-Smith, Y Ning

Mechanism of enhanced cyclic AMP stimulation by isoproterenol in aged human fibroblasts

Jan 11, 1992·Experimental Gerontology·M F EthierJ G Dobson

Aging, longevity, and immortality in vitro

Jul 1, 1992·Experimental Gerontology·L Hayflick

The telomere hypothesis of cellular aging

Jul 1, 1992·Experimental Gerontology·C B HarleyR C Allsopp

Oncogenes, protooncogenes, and tumor suppressor genes: a hitchhiker's guide to senescence?

Jul 1, 1992·Experimental Gerontology·J Campisi

Altered expression of cell cycle dependent genes in senescent WI-38 cells

Jul 1, 1992·Experimental Gerontology·P D Phillips, R J Pignolo

Are all nonproliferating cells similar?

Jul 1, 1992·Experimental Gerontology·E Wang

Metalloproteinase and TIMP-1 gene expression during replicative senescence

Jul 1, 1992·Experimental Gerontology·A J MillisC Baglioni

Changes in gene expression during senescence in culture

Jul 1, 1992·Experimental Gerontology·V J CristofaloM O Rotenberg

Molecular genetic approaches to the study of cellular aging

Jul 1, 1992·Experimental Gerontology·Olivia M Pereira-Smith

Werner syndrome: molecular genetics and mechanistic hypotheses

Jul 11, 1992·Experimental Gerontology·R J Monnat

Timekeeping in genetically programmed aging

Mar 1, 1993·Experimental Gerontology·P E KloedenO E Rössler

Accumulation of a senescence factor in yeast cells

Mar 1, 1993·Experimental Gerontology·H R Hirsch

Contributions made by the studies of cells in vitro for understanding of the mechanisms of aging

Jan 1, 1993·Experimental Gerontology·A Macieira-Coelho

Metallothionein expression and stress responses in aging human diploid fibroblasts

Jan 1, 1993·Experimental Gerontology·M C LuceC L Bunn

Growth properties of familial Alzheimer skin fibroblasts during in vitro aging

Jan 1, 1993·Experimental Gerontology·G TescoS Sorbi

Stimulation of cell proliferation by hyaluronidase during in vitro aging of human skin fibroblasts

Jan 1, 1993·Experimental Gerontology·M Moczar, L Robert

Expression of interleukin-1 alpha and beta in early passage fibroblasts from aging individuals

Nov 1, 1993·Experimental Gerontology·S KumarC Baglioni

Physiological oxygen tension is relevant to MHC-1 expression, spontaneous transformation, and interferon response of in vitro aging murine fibroblasts

Nov 1, 1993·Experimental Gerontology·P EbbesenV Zachar

Insulin-like growth factor binding protein-3 is overexpressed in senescent and quiescent human fibroblasts

Jul 1, 1993·Experimental Gerontology·E J MoermanS Goldstein

The pineal gland and melatonin in relation to aging: a summary of the theories and of the data

May 1, 1995·Experimental Gerontology·R J Reiter

Prohibitin: potential role in senescence, development, and tumor suppression

Mar 1, 1995·Experimental Gerontology·J K McClungR T Dell'Orco

Nuclear matrix composition and in vitro cellular senescence

Mar 1, 1994·Experimental Gerontology·R T Dell'Orco, W L Whittle

Altered transcriptional regulation of human interstitial collagenase in cultured skin fibroblasts from older donors

Jan 1, 1994·Experimental Gerontology·E M BurkeG M Martin

Decline in CD28+ T cells in centenarians and in long-term T cell cultures: a possible cause for both in vivo and in vitro immunosenescence

Nov 1, 1994·Experimental Gerontology·R B EffrosF Schächter

Life span prediction from the rate of age-related DNA demethylation in normal and cancer cell lines

Sep 1, 1995·Experimental Gerontology·A L Mazin

Insights on immunological aging derived from the T lymphocyte cellular senescence model

Jan 1, 1996·Experimental Gerontology·R B Effros

Screening for genetic predisposition to mutagens in cancer patients

Jan 1, 1996·Experimental Gerontology·R S GuptaS Goldstein

Differential CDK-inhibitor gene expression in aging human diploid fibroblasts

Jan 1, 1996·Experimental Gerontology·H Wong, Karl Riabowol

Studies demonstrating the complexity of regulation and action of the growth inhibitory gene SDI1

Jan 1, 1996·Experimental Gerontology·J R SmithOlivia M Pereira-Smith

Prohibitin and the senescent phenotype

Jan 1, 1996·Experimental Gerontology·R T Dell'OrcoX T Liu

Proliferative cell senescence, transformation, and the recombination potential of the genome

Jan 1, 1996·Experimental Gerontology·A Macieira-Coelho

Identification of gene sequences overexpressed in senescent and Werner syndrome human fibroblasts

Jan 1, 1996·Experimental Gerontology·B Lecka-CzernikS Goldstein

Molecular markers of senescence in fibroblast-like cultures

Jan 1, 1996·Experimental Gerontology·V J Cristofalo, R J Pignolo

Increased susceptibility of late passage human diploid fibroblasts to oxidative stress

Jul 1, 1996·Experimental Gerontology·H YuanM Matsuo

Telomeres, telomerase, and aging: origin of the theory

Jul 1, 1996·Experimental Gerontology·A M Olovnikov

Expression of HLA-DR antigen and smooth muscle cell differentiation markers by valvular fibroblasts in degenerative aortic stenosis

Dec 1, 1994·Journal of the American College of Cardiology·M OlssonJ Nilsson

Temporal effects of ethanol on growth, thymidine uptake, protein and collagen production in human foetal lung fibroblasts

Jan 1, 1990·Toxicology in Vitro : an International Journal Published in Association with BIBRA·Y BarnesF A Barile

A study of mitotic division fidelity and numerical chromosome changes in ageing Syrian hamster dermal cells

Mar 1, 1990·Mutation Research·E M ParryJ M Parry

Glycosylases that excise modified DNA pyrimidines in young and senescent human WI-38 fibroblasts

Mar 1, 1990·Mutation Research·T Ganguly, N J Duker

Aging under glass

Mar 1, 1991·Mutation Research·L Hayflick

Actin cytoskeletal network in aging and cancer

Mar 1, 1991·Mutation Research·K M Rao, H J Cohen

Changes in the cell surface of human diploid fibroblasts during cellular aging

Mar 1, 1991·Mutation Research·K Yamamoto, M Yamamoto

Cellular ageing of Alzheimer's disease and Down syndrome cells in culture

Mar 1, 1991·Mutation Research·G CarmelietJ J Cassiman

Negative growth effectors and cellular senescence

Mar 1, 1991·Mutation Research·A L Spiering, J R Smith

Telomere loss: mitotic clock or genetic time bomb?

Mar 1, 1991·Mutation Research·C B Harley

A re-examination of the effects of ionizing radiation on lifespan and transformation of human diploid fibroblasts

Mar 1, 1991·Mutation Research·R Holliday

Molecular genetic approaches to the study of cellular senescence

Mar 1, 1991·Mutation Research·Y Ning, Olivia M Pereira-Smith

Reduced 5-hydroxymethyluracil-DNA glycosylase activity in Werner's syndrome cells

Mar 1, 1992·Mutation Research·T Ganguly, N J Duker

Biomarkers of aging: correlation of DNA I-compound levels with median lifespan of calorically restricted and ad libitum fed rats and mice

Dec 1, 1993·Mutation Research·K RanderathE Randerath

Cloning of cDNAs with possible association with senescence and immortalization of human cells

Feb 1, 1994·Mutation Research·Y SatohS Gotoh

Correlation between senescence and DNA repair in cells from young and old individuals and in premature aging syndromes

Feb 1, 1994·Mutation Research·H Weirich-SchwaigerM Hirsch-Kauffmann

Nucleic acid fingerprinting by PCR-based methods: applications to problems in aging and mutagenesis

Oct 1, 1995·Mutation Research·J WelshM Perucho

Changes of the methylation pattern of the c-myc gene during in vitro aging of IMR90 human embryonic fibroblasts

May 1, 1995·Mutation Research·J P HalleG Adam

A re-examination of the intragenome distribution of repaired sites in proliferating xeroderma pigmentosum complementation group C fibroblasts

Nov 1, 1992·Mutation Research·G J Kantor, G A Shanower

Repair of some active genes in Cockayne syndrome cells is at the genome overall rate

May 1, 1995·Mutation Research·G J Kantor, S A Bastin

DNA repair in the genomic region containing the beta-actin gene in xeroderma pigmentosum complementation group C and normal human cells

Jul 1, 1994·Mutation Research·L S BarsalouC E Hall

Apoptosis, senescence, immortalization and cancer

Dec 1, 1994·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·V ChiarugiM Ruggiero

Age-related alterations in collagen and total protein metabolism determined in cultured rat dermal fibroblasts: age-related trends parallel those observed in rat skin in vivo

Sep 1, 1995·The International Journal of Biochemistry & Cell Biology·P K MaysG J Laurent

Mesothelial cell: a multifaceted model of aging

Feb 19, 2013·Ageing Research Reviews·Krzysztof Ksiazek

Aging-associated increase of gelsolin for apoptosis resistance

Dec 4, 2003·Biochemical and Biophysical Research Communications·Jeong Soo AhnSang Chul Park

Studying the capability of different cancer hallmarks to initiate tumor growth using a cellular automaton simulation. Application in a cancer stem cell context

Nov 23, 2013·Bio Systems·Ángel Monteagudo, José Santos

Induction and repair of radiation-induced DNA double-strand breaks in human fibroblasts are not affected by terminal differentiation

Jan 7, 2004·DNA Repair·Ingo BrammerEkkehard Dikomey

Living forever and dying in the attempt

Dec 31, 2003·Experimental Gerontology·L Hayflick

Replicative enzymes, DNA polymerase alpha (pol alpha), and in vitro ageing

Dec 31, 2003·Experimental Gerontology·Vinod K Srivastava, David L Busbee

mRNA level of alpha-2-macroglobulin as an aging biomarker of human fibroblasts in culture

Mar 24, 2004·Experimental Gerontology·Hong MaTanjun Tong

Proteasome inhibition increases HuR level, restores heat-inducible HSP72 expression and thermotolerance in WI-38 senescent human fibroblasts

Mar 24, 2004·Experimental Gerontology·Mara A BonelliAngelo F Borghetti

Autolysosomes accumulate during in vitro CD8+ T-lymphocyte aging and may participate in induced death sensitization of senescent cells

May 8, 2004·Experimental Gerontology·Luc-Marie GerlandMartine Ffrench

The aging myocardium: roles of mitochondrial damage and lysosomal degradation

Dec 15, 2005·Heart, Lung & Circulation·A Terman, U T Brunk

Establishment and partial characterization of an ovine synovial membrane cell line obtained by transformation with Simian Virus 40 T antigen

May 21, 2005·Journal of Virological Methods·U M CostaA P Ravazzolo

HDTIC-1 and HDTIC-2, two compounds extracted from Astragali Radix, delay replicative senescence of human diploid fibroblasts

Dec 9, 2003·Mechanisms of Ageing and Development·Peichang WangTanjun Tong

Selective COX-2 inhibitor, NS-398, inhibits the replicative senescence of cultured dermal fibroblasts

May 8, 2004·Mechanisms of Ageing and Development·Ji Hyun HanJin Ho Chung

The role of telomeres in skin aging/photoaging

Mar 24, 2004·Micron : the International Research and Review Journal for Microscopy·M G Kosmadaki, B A Gilchrest

From Weismann's theory to present day gerontology 1889-2003

Nov 19, 2003·Pathologie-biologie·A Macieira-Coelho

Telomerase: central regulator of all of the hallmarks of cancer

Aug 13, 2013·Trends in Biochemical Sciences·Kee Chung Low, Vinay Tergaonkar

Histone deacetylase inhibitors induce a senescence-like state in human cells by a p16-dependent mechanism that is independent of a mitotic clock

Apr 20, 2004·Experimental Cell Research·June MunroE K Parkinson

Loss of heterozygosity on chromosome 7q in in vitro-immortalized human oral keratinocyte cell lines

Sep 11, 2002·Archives of Oral Biology·Yasuhito AraiTakeki Tsutsui

Bcl-2 can promote p53-dependent senescence versus apoptosis without affecting the G1/S transition

Oct 22, 2002·Biochemical and Biophysical Research Communications·Vincent RinchevalJean-Luc Vayssière

The in vitro cultivation and differentiation capacities of myogenic cell lines

Sep 1, 1970·Developmental Biology·C Richler, D Yaffe

An analysis of replicative senescence in dermal fibroblasts derived from chronic leg wounds predicts that telomerase therapy would fail to reverse their disease-specific cellular and proteolytic phenotype

Feb 5, 2003·Experimental Cell Research·Phil StephensDavid W Thomas

Mutant p53 can delay growth arrest and loss of CDK2 activity in senescing human fibroblasts without reducing p21(WAF1) expression

Apr 23, 2003·Experimental Cell Research·Fiona WyllieD Wynford-Thomas

Senescence-associated genes in normal human oral keratinocytes

Jul 3, 2003·Experimental Cell Research·Mo K KangNo-Hee Park

An in silico investigation into the causes of telomere length heterogeneity and its implications for the Hayflick limit

Oct 25, 2003·Journal of Theoretical Biology·A GolubevA Butov

Ultrastructural and cytochemical changes in cultured human lung cells

Jun 1, 1972·Journal of Ultrastructure Research·D BrandesS Barnard

The inhibition of DNA repair capacity by stilbene estrogen in Leydig cells: its implications in the induction of instability in the testicular genome

Oct 16, 2001·Mutation Research·J W DuMond, D Roy

Cellular senescence: a new marker of kidney function recovery after ischemic injury in rats

Sep 7, 2001·Transplantation Proceedings·A ChkhotuaA Yussim

Telomerase and mammalian ageing: a critical appraisal

May 9, 2000·Mechanisms of Ageing and Development·Malcolm H Goyns, W L Lavery

Articular chondrocytes from aging rats respond poorly to insulin-like growth factor-1: an altered signaling pathway

Jun 16, 2000·Mechanisms of Ageing and Development·H MessaiD R Mitrovic

Effects of ageing on proliferative ability, and the expressions of secreted protein, acidic and rich in cysteine (SPARC) and osteoprotegerin (osteoclastogenesis inhibitory factor) in cultures of human periodontal ligament cells

Aug 26, 2000·Mechanisms of Ageing and Development·H ShibaH Kurihara

On the nature of aging

Aug 26, 2000·Mechanisms of Ageing and Development·I Semsei

DNA damage susceptibility and repair in correlation to calendric age and longevity

Nov 18, 2000·Mechanisms of Ageing and Development·R K ZahnM Hosokawa

A cell kinetic analysis of human umbilical vein endothelial cells

Nov 23, 2000·Mechanisms of Ageing and Development·L KalashnikR G Faragher

The budding yeast, Saccharomyces cerevisiae, as a model for aging research: a critical review

Nov 23, 2000·Mechanisms of Ageing and Development·H Gershon, D Gershon

Werner's syndrome T lymphocytes display a normal in vitro life-span

Feb 13, 2001·Mechanisms of Ageing and Development·S E JamesL V Mayne

Molecular mechanisms of ageing in connective tissues

Apr 27, 2001·Mechanisms of Ageing and Development·A J Bailey

Endothelin-1 receptors on cultured rat articular chondrocytes: regulation by age, growth factors, and cytokines, and effect on cAMP production

Apr 11, 2001·Mechanisms of Ageing and Development·H MessaiD R Mitrovic

Enhancement of lipopolysaccharide-stimulated cyclooxygenase-2 mRNA expression and prostaglandin E2 production in gingival fibroblasts from individuals with Down syndrome

Feb 19, 2002·Mechanisms of Ageing and Development·Yoko OtsukaJunichi Mega

Genes, telomeres and mammalian ageing

Mar 1, 2002·Mechanisms of Ageing and Development·Malcolm H Goyns

Molecular mechanisms of skin ageing

Mar 1, 2002·Mechanisms of Ageing and Development·Gail Jenkins

Genetics of cellular senescence

Jun 5, 2002·Mechanisms of Ageing and Development·Kaoru TominagaOlivia M Pereira-Smith

In vitro aging of macaque adherent cells: similar pattern of cellular aging between human and macaque

Mar 14, 2003·Mechanisms of Ageing and Development·Yuko ShimizuTakafumi Ishida

Models of accelerated ageing can be informative about the molecular mechanisms of ageing and/or age-related pathology

May 9, 2003·Mechanisms of Ageing and Development·Huber R Warner, Felipe Sierra

Effects of in vitro cellular aging on alkaline phosphatase, cathepsin activities and collagen secretion of human periodontal ligament derived cells

Nov 13, 1996·Mechanisms of Ageing and Development·T GosekiY Abiko

In vitro study of gingival fibroblasts from normal and inflamed tissue: age-related responsiveness

Nov 29, 1996·Mechanisms of Ageing and Development·R SolmiG Biagini

Cell aging in vivo and in vitro

Oct 1, 1997·Mechanisms of Ageing and Development·H Rubin

Contribution of IL-1 beta to the enhancement of Campylobacter rectus lipopolysaccharide-stimulated PGE2 production in old gingival fibroblasts in vitro

Oct 1, 1997·Mechanisms of Ageing and Development·H TakiguchiY Abiko

Age changes in signal transduction and gene expression

Nov 14, 1997·Mechanisms of Ageing and Development·G S Roth

Hierarchical deterioration of body systems in Werner's syndrome: implications for normal ageing

Nov 14, 1997·Mechanisms of Ageing and Development·M Goto

Age-related decrease in the responsiveness of rat articular chondrocytes to EGF is associated with diminished number and affinity for the ligand of cell surface binding sites

Mar 24, 1998·Mechanisms of Ageing and Development·D RibaultD R Mitrovic

Enhanced expression of mitochondrial genes in senescent endothelial cells and fibroblasts

May 21, 1998·Mechanisms of Ageing and Development·T KumazakiY Mitsui

Cell kinetics of hemopoietic colony-forming units in spleen (CFU-S) in young and old mice

Jun 11, 1998·Mechanisms of Ageing and Development·Y HirabayashiT Inoue

Neutral endopeptidase-24.11 (NEP) activity in human fibroblasts during development and ageing

Jul 15, 1998·Mechanisms of Ageing and Development·D KletsasE Ottaviani

Effect of age and apoptosis on the mouse homologue of the huWRN gene

Jul 29, 1998·Mechanisms of Ageing and Development·J WuJ D Mountz

Mitogenic factors accelerate later-age diseases: insulin as a paradigm

Jul 15, 1998·Mechanisms of Ageing and Development·A Lev-Ran

Markers of 'cell senescence'

Oct 29, 1998·Mechanisms of Ageing and Development·A Macieira-Coelho

Ceroid/lipofuscin formation in cultured human fibroblasts: the role of oxidative stress and lysosomal proteolysis

Nov 18, 1998·Mechanisms of Ageing and Development·A Terman, U T Brunk

Expressional changes in alternative splicing affecting genes during cell passage of human diploid fibroblasts

Jan 28, 1999·Mechanisms of Ageing and Development·Y ItoY Mitsui

Changes in the expression of protein kinase C (PKC), phospholipases C (PLC) and D (PLD) isoforms in spleen, brain and kidney of the aged rat: RT-PCR and Western blot analysis

Jan 28, 1999·Mechanisms of Ageing and Development·T MizutaniY Nozawa

Effect of cellular aging on the induction of cyclooxygenase-2 by mechanical stress in human periodontal ligament cells

Jul 10, 1999·Mechanisms of Ageing and Development·K OhzekiY Abiko

Age-related loss of proliferative activity of human vascular smooth muscle cells in culture

Dec 2, 1999·Mechanisms of Ageing and Development·A Ruiz-TorresM Macía

Sudden senescence syndrome plays a major role in cell culture proliferation

Feb 25, 2000·Mechanisms of Ageing and Development·Ivica RubeljB Brdar

Mechanical stress enhances expression and production of plasminogen activator in aging human periodontal ligament cells

Feb 25, 2000·Mechanisms of Ageing and Development·S MiuraY Abiko

Endothelin-1 in monolayer cultures of articular chondrocytes from young and old rats: regulation by growth factors and cytokines

Mar 25, 2000·Mechanisms of Ageing and Development·H MessaiD R Mitrovic

Expression of senescence-associated beta-galactosidase in enlarged prostates from men with benign prostatic hyperplasia

Jun 28, 2000·Urology·J ChoiM C Benson

Study of the population dynamics of the human diploid cell strain WI-38. II. The composition of the medium

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Apr 9, 2002·Lancet·Dennis A Steindler, David W Pincus

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Human bone cell cultures in biocompatibility testing. Part I: osteoblastic differentiation of serially passaged human bone marrow cells cultured in alpha-MEM and in DMEM

May 19, 2000·Biomaterials·M J CoelhoM H Fernande

Telomerase expression and telomere length in immortal leukocyte lines from channel catfish

Jun 1, 2000·Developmental and Comparative Immunology·K S BarkerN W Miller

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Human malignant cell death by apoptosis-inducing nucleosides from the decidua derived CD57(+)HLA-DR(bright) natural suppressor cell line

Dec 4, 2001·Journal of Reproductive Immunology·Tsuneatsu MoriEtsuko Mori

Fish immunology: the utility of immortalized lymphoid cells--a mini review

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Aneuploidy theory explains tumor formation, the absence of immune surveillance, and the failure of chemotherapy

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Cell senescence and a mechanism of clonal evolution leading to continuous cell proliferation, loss of heterozygosity, and tumor heterogeneity: studies on two immortal colon cancer cell lines

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Promise and problems in relating cellular senescence in vitro to aging in vivo

Feb 7, 2004·Archives of Gerontology and Geriatrics·H Rubin

Thymocytopoiesis in aging: the bone marrow-thymus axis

Mar 1, 1997·Archives of Gerontology and Geriatrics·A Globerson

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Apr 9, 2001·Trends in Biotechnology·D Gems

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Jul 1, 1988·Collagen and Related Research·J SottileA J Millis

Establishment and characterization of a new clonal strain derived from human benign gastric teratoma

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Longitudinal studies of telomere length in feline blood cells: implications for hematopoietic stem cell turnover in vivo

Oct 18, 2002·Experimental Hematology·T H BrümmendorfPeter M Lansdorp

Hematopoietic senescence is postponed and hematopoietic stem cell function is enhanced by dietary restriction

Oct 31, 2003·Experimental Hematology·Jichun ChenD E Harrison

Development and aging of primitive hematopoietic stem cells in BALB/cBy mice

May 26, 1999·Experimental Hematology·J ChenD E Harrison

Genetic regulation of primitive hematopoietic stem cell senescence

Apr 27, 2000·Experimental Hematology·J ChenD E Harrison

Correlation of telomere lengths in normal and cancers tissue in the large bowel

Aug 29, 2000·Cancer Letters·K NakamuraK Takubo

Telomeres and replicative senescence: Is it only length that counts?

Jun 19, 2001·Cancer Letters·T von Zglinicki

Green tea epigallocatechin gallate shows a pronounced growth inhibitory effect on cancerous cells but not on their normal counterparts

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Apoptosis is induced in aging SV40 T antigen-transformed human fibroblasts through p53- and p21CIP1/WAF1-independent pathways

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Cloning the AFURS1 gene which is up-regulated in senescent human parenchymal kidney cells

Feb 28, 2002·Gene·Negusse Habtemichael, Gyula Kovacs

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Mar 10, 1997·Gene·S M WangF Sierra

SEMP1, a senescence-associated cDNA isolated from human mammary epithelial cells, is a member of an epithelial membrane protein superfamily

Feb 5, 1999·Gene·K SwisshelmS Hosier

Telomeres, replicative senescence and human ageing

Apr 20, 2001·Maturitas·D Kipling

Ovarian ageing and the general biology of senescence

Jan 1, 1999·Maturitas·T B Kirkwood

Biogerontological research in Canada

Jun 1, 2000·Experimental Gerontology·T Fulop

Senescence-like changes induced by hydroxyurea in human diploid fibroblasts

Sep 9, 2000·Experimental Gerontology·E J YeoS C Park

Skeletal muscle regeneration and the mitotic clock

Oct 29, 2000·Experimental Gerontology·Valérie RenaultVincent Mouly

Spontaneous and radiation-induced differentiationof fibroblasts

Oct 29, 2000·Experimental Gerontology·C Herskind, H P Rodemann

Graying: gerontobiology of the hair follicle pigmentary unit

Feb 13, 2001·Experimental Gerontology·D J Tobin, R Paus

Induction of senescence-associated genes by 5-bromodeoxyuridine in HeLa cells

Mar 16, 2001·Experimental Gerontology·T SuzukiDai Ayusawa

Two-dimensional gel electrophoretic studies on the cellular aging: accumulation of alpha-2-macroglobulin in human fibroblasts with aging

Mar 16, 2001·Experimental Gerontology·T KondoM Namba

Up-regulation of S100C in normal human fibroblasts in the process of aging in vitro

Oct 17, 2001·Experimental Gerontology·M SakaguchiM Namba

The human melanocyte: a model system to study the complexity of cellular aging and transformation in non-fibroblastic cells

Oct 17, 2001·Experimental Gerontology·D BandyopadhyayEstela E Medrano

Critical assessment of paradigms in aging research

Jun 19, 2001·Experimental Gerontology·H Gershon, D Gershon

Telomere shortening with aging in human thyroid and parathyroid tissue

Feb 7, 2002·Experimental Gerontology·M KammoriK Takubo

Telomere lengths are characteristic in each human individual

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Twenty years of ageing research at the Mill Hill laboratories

Jun 28, 2002·Experimental Gerontology·R Holliday

Changes in nuclear matrix proteins during the senescence-like phenomenon induced by 5-chlorodeoxyuridine in HeLa cells

Jun 28, 2002·Experimental Gerontology·Eriko MichishitaDai Ayusawa

Demethylation of classical satellite 2 and 3 DNA with chromosomal instability in senescent human fibroblasts

Sep 6, 2002·Experimental Gerontology·Toshikazu SuzukiDai Ayusawa

Human skeletal muscle satellite cells: aging, oxidative stress and the mitotic clock

Dec 10, 2002·Experimental Gerontology·Valérie RenaultVincent Mouly

Role of the Raf/MEK/ERK and the PI3K/Akt(PKB) pathways in fibroblast senescence

Dec 10, 2002·Experimental Gerontology·Antonello LorenziniV J Cristofalo

Association of increased autophagic inclusions labeled for beta-galactosidase with fibroblastic aging

Aug 14, 2003·Experimental Gerontology·Luc-Marie GerlandMartine Ffrench

A proton magnetic resonance spectroscopy study of aging and transformed human fibroblasts

Nov 1, 1996·Experimental Gerontology·A RutterC E Mountford

An update on the oxygen stress-mitochondrial mutation theory of aging: genetic and evolutionary implications

Feb 19, 1998·Experimental Gerontology·J Miquel

Alex Comfort: clearing the way for future research

Feb 19, 1998·Experimental Gerontology·R Holliday

A consideration of some notable aging theories

Feb 19, 1998·Experimental Gerontology·J C Carlson, J C Riley

Molecular aspects of the relationship between cancer and aging: tumor suppressor activity during cellular senescence

Feb 19, 1998·Experimental Gerontology·I GarkavtsevKarl Riabowol

The pathway of cell senescence: WI-38 cells arrest in late G1 and are unable to traverse the cell cycle from a true G0 state

Feb 19, 1998·Experimental Gerontology·R J PignoloV J Cristofalo

Reassessment of immortalization complementation group D

Oct 24, 1998·Experimental Gerontology·E L MoyRoger R Reddel

Identification of altered expression of ADP/ATP translocase during cellular senescence in vitro

Oct 8, 1998·Experimental Gerontology·W FanE C LeRoy

CD28 expression in T cell aging and human longevity

Jun 6, 1998·Experimental Gerontology·N BoucherF Schächter

The two-process model of cellular aging

Oct 8, 1998·Experimental Gerontology·H Kitano, S Imai

How and why we age

Feb 10, 1999·Experimental Gerontology·L Hayflick

Transgenic mouse models of muscle aging

Jun 11, 1999·Experimental Gerontology·A Musarò, N Rosenthal

Enhancement of lipopolysaccharide-stimulated PGE2 and IL-1beta production in gingival fibroblast cells from old rats

Aug 5, 1999·Experimental Gerontology·H OkamuraY Abiko

Histone variants of H2A and H3 families are regulated during in vitro aging in the same manner as during differentiation

Dec 1, 1999·Experimental Gerontology·E P Rogakou, K E Sekeri-Pataryas

Ceroid/lipofuscin-loaded human fibroblasts show decreased survival time and diminished autophagocytosis during amino acid starvation

Feb 15, 2000·Experimental Gerontology·A TermanU T Brunk

Genetic approaches to the study of replicative senescence

Mar 8, 2000·Experimental Gerontology·Q Ran, Olivia M Pereira-Smith

cRel induces mitochondrial alterations in correlation with proliferation arrest

Oct 12, 2001·Free Radical Biology & Medicine·D BernardC Abbadie

Relief of oxidative stress by ascorbic acid delays cellular senescence of normal human and Werner syndrome fibroblast cells

Aug 6, 2003·Free Radical Biology & Medicine·Genro KashinoMasami Watanabe

Accelerated telomere shortening in fibroblasts after extended periods of confluency

Jun 2, 1998·Free Radical Biology & Medicine·N SitteT von Zglinicki

Age-dependent increase of collagenase expression can be reduced by alpha-tocopherol via protein kinase C inhibition

Oct 9, 1999·Free Radical Biology & Medicine·R RicciarelliA Azzi

Protein oxidation and degradation during proliferative senescence of human MRC-5 fibroblasts

Apr 8, 2000·Free Radical Biology & Medicine·N SitteT Grune

Accumulation of oxidative DNA damage, 8-oxo-2'-deoxyguanosine, and change of repair systems during in vitro cellular aging of cultured human skin fibroblasts

Oct 12, 2001·Mutation Research·T KanekoH Kondo

Achievements and future of chemotherapy

Aug 10, 2000·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·J Verweij, M J de Jonge

Cell biology of precancer

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The biology of replicative senescence

Apr 1, 1997·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·J Campisi

Enhanced invasiveness of tumour cells after host exposure to heavy metals

Dec 1, 1996·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·A HagaT Sato

The genetic basis of human keratinocyte immortalisation in squamous cell carcinoma development: the role of telomerase reactivation

Apr 1, 1997·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·E K ParkinsonW Nicol Keith

Establishment of human cementifying fibroma cell lines by transfection with temperature-sensitive simian virus-40 T-antigen gene and hTERT gene

May 9, 2002·Bone·Y KudoT Takata

THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS

Abstract

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