The linear nonthreshold (LNT) model as used in radiation protection: an NCRP update

International Journal of Radiation Biology
J D Boice

Abstract

The linear nonthreshold (LNT) model has been used in radiation protection for over 40 years and has been hotly debated. It relies heavily on human epidemiology, with support from radiobiology. The scientific underpinnings include NCRP Report No. 136 ('Evaluation of the Linear-Nonthreshold Dose-Response Model for Ionizing Radiation'), UNSCEAR 2000, ICRP Publication 99 (2004) and the National Academies BEIR VII Report (2006). NCRP Scientific Committee 1-25 is reviewing recent epidemiologic studies focusing on dose-response models, including threshold, and the relevance to radiation protection. Recent studies after the BEIR VII Report are being critically reviewed and include atomic-bomb survivors, Mayak workers, atomic veterans, populations on the Techa River, U.S. radiological technologists, the U.S. Million Person Study, international workers (INWORKS), Chernobyl cleanup workers, children given computerized tomography scans, and tuberculosis-fluoroscopy patients. Methodologic limitations, dose uncertainties and statistical approaches (and modeling assumptions) are being systematically evaluated. The review of studies continues and will be published as an NCRP commentary in 2017. Most studies reviewed to date are consistent with...Continue Reading

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Citations

Jun 22, 2017·International Journal of Radiation Biology·Kathryn D Held, Nobuyuki Hamada
Jun 15, 2017·International Journal of Radiation Biology·Nobuyuki HamadaJohn D Boice
May 23, 2018·Health Physics·Carmel Mothersill, Colin Seymour
Mar 24, 2018·International Journal of Radiation Biology·Scott Bright, Munira Kadhim
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Mar 5, 2019·International Journal of Radiation Biology·John D Boice
Mar 5, 2019·International Journal of Radiation Biology·John D BoiceElizabeth D Ellis
Oct 30, 2018·Toxicological Research·Takehiko Nohmi
Feb 23, 2019·Journal of Radiological Protection : Official Journal of the Society for Radiological Protection·Daniele Giuffrida
Mar 26, 2019·Health Physics·Julie E Leblanc, Julie J Burtt
Jul 5, 2019·Journal of Radiological Protection : Official Journal of the Society for Radiological Protection·John D BoiceRoy Shore
Sep 8, 2020·International Archives of Occupational and Environmental Health·Won Jin LeeSung Bum Cho
Jan 24, 2018·Health Physics·John D Boice
Sep 17, 2020·International Journal of Molecular Sciences·Usha KabilanDmitry Klokov
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Jun 21, 2019·Dose-response : a Publication of International Hormesis Society·Yehoshua SocolMoshe Yanovskiy
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Jul 1, 2021·The British Journal of Radiology·Ming Tsuey ChewDavid A Bradley
Nov 4, 2021·International Journal of Radiation Biology·John D BoiceLawrence T Dauer

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