The lipid droplet-a well-connected organelle

Frontiers in Cell and Developmental Biology
Qiang Gao, Joel M Goodman

Abstract

Our knowledge of inter-organellar communication has grown exponentially in recent years. This review focuses on the interactions that cytoplasmic lipid droplets have with other organelles. Twenty-five years ago droplets were considered simply particles of coalesced fat. Ten years ago there were hints from proteomics studies that droplets might interact with other structures to share lipids and proteins. Now it is clear that the droplets interact with many if not most cellular structures to maintain cellular homeostasis and to buffer against insults such as starvation. The evidence for this statement, as well as probes to understand the nature and results of droplet interactions, are presented.

References

Nov 1, 1991·The Journal of Cell Biology·K D Chapman, R N Trelease
Jun 1, 1987·Yeast·M VeenhuisW Harder
Dec 1, 1966·The Journal of Cell Biology·E J Blanchette
Oct 1, 1980·The Journal of Cell Biology·A B NovikoffC S Rubin
Oct 23, 2001·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·M Schrader
Sep 11, 2002·The Journal of Biological Chemistry·Kumi Tauchi-SatoToyoshi Fujimoto
Dec 6, 2002·Applied Microbiology and Biotechnology·H M Alvarez, A Steinbüchel
Sep 1, 2004·Biochemical and Biophysical Research Communications·Noriko NakamuraToyoshi Fujimoto
Feb 21, 2006·The Journal of Biological Chemistry·Amy MarcinkiewiczDawn L Brasaemle
Oct 1, 1969·Plant Physiology·B P Gerhardt, H Beevers
Jun 1, 2006·The Journal of Cell Biology·Derk BinnsJoel M Goodman
Sep 12, 2006·FEBS Letters·Nathan E WolinsPerry E Bickel
Sep 19, 2006·Current Biology : CB·Silvia CermelliMichael A Welte
Nov 11, 2006·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Mark A TarnopolskyMazen J Hamadeh
Mar 31, 2007·Biochimica Et Biophysica Acta·Pingsheng LiuRichard G W Anderson
Sep 4, 2007·Trends in Cell Biology·Michael A Welte
Sep 22, 2007·The Journal of Biological Chemistry·Vishwajeet PuriMichael P Czech
Dec 21, 2007·Proceedings of the National Academy of Sciences of the United States of America·Kimberly M SzymanskiJoel M Goodman
Jul 2, 2008·Proceedings of the National Academy of Sciences of the United States of America·Jordan L CocchiaroRaphael H Valdivia
Jul 10, 2008·The Journal of Biological Chemistry·Joel M Goodman
Dec 11, 2008·PLoS Biology·Mathias BellerBrian Oliver
Apr 3, 2009·Nature·Rajat SinghMark J Czaja
Jul 28, 2009·FEBS Letters·R BeckD Cassel
Oct 22, 2009·American Journal of Physiology. Endocrinology and Metabolism·Kun LiuCynthia M Smas
Oct 27, 2009·The Journal of Clinical Investigation·Rajat SinghMark J Czaja
Oct 31, 2009·Traffic·Mercedes Ingelmo-TorresAlbert Pol
Feb 15, 2011·FEBS Letters·Agné KulytéJurga Laurencikiene
Apr 26, 2011·Trends in Cell Biology·Ashraf MalhasDavid J Vaux
Jun 23, 2011·Journal of Cell Science·Nicolas JacquierRoger Schneiter
Jun 23, 2011·The Journal of Biological Chemistry·James A Olzmann, Ron R Kopito

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Citations

Dec 2, 2015·The Journal of Cell Biology·Sofia C GuimaraesGero Steinberg
Jan 6, 2016·The Journal of Cell Biology·Robert V Farese, Tobias C Walther
Oct 30, 2016·Cellular Microbiology·Philippe Roingeard, Rossana C N Melo
Jan 22, 2017·The Journal of Cell Biology·Joseph L CostelloMichael Schrader
Nov 23, 2016·Scientific Reports·Kai BiTao Chen
Apr 1, 2017·Nature Communications·Simon G PfistererElina Ikonen
Apr 12, 2017·International Journal of Molecular Sciences·Elif GuzelUmit Ali Kayisli
Dec 8, 2017·Plant, Cell & Environment·Koji YamaneMitsutaka Taniguchi
Mar 14, 2019·Journal of Inherited Metabolic Disease·Michael SchraderMarkus Islinger
Apr 21, 2018·Biological Trace Element Research·Marek KieliszekAnna M Kot
Jul 10, 2018·Pflügers Archiv : European journal of physiology·Alexei V Tepikin
Mar 31, 2019·Journal of Lipid Research·Tarik ExnerJoachim Füllekrug
Apr 8, 2017·Cell Death Discovery·Johannes BischofMark Rinnerthaler
Aug 11, 2017·Annual Review of Cell and Developmental Biology·Tobias C WaltherRobert V Farese
Sep 6, 2017·Biomolecules·Françoise M RoelantsJeremy Thorner
Aug 3, 2019·International Journal of Molecular Sciences·Elena LonatiAlessandra Bulbarelli
Jul 8, 2020·International Journal of Molecular Sciences·Karamat MohammadVladimir I Titorenko
Sep 2, 2020·Proceedings of the National Academy of Sciences of the United States of America·Jihyeon LeeYoungsook Lee
May 24, 2018·Histochemistry and Cell Biology·Manja Luckner, Gerhard Wanner
Feb 5, 2019·Frontiers in Plant Science·Morgane Michaud, Juliette Jouhet

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Methods Mentioned

BETA
electron microscopy
fluorescence microscopy
glycosylation

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