PMID: 6409610Aug 1, 1983Paper

The lipopolysaccharide from Pseudomonas aeruginosa NCTC 8505. Structure of the O-specific polysaccharide

European Journal of Biochemistry
Y Tahara, S G Wilkinson

Abstract

Structural studies have been carried out on the O-specific fraction from the lipopolysaccharide of Pseudomonas aeruginosa NCTC 8505, Habs serotype 03. The O-specific polysaccharide has a tetrasaccharide repeating-unit containing residues of L-rhamnose (Rha), 2-acetamido-2-deoxy-D-glucose (GlcNAc), 2-acetamido-2-deoxy-L-galacturonic acid (GalNAcA), and 2,4-diacetamido-2,4,6-trideoxy-D-glucose (BacNAc2). The following structure has been assigned to the repeating-unit: leads to 3)Rhap(beta 1 leads to 6)GlcpNAc(alpha 1 leads to 4)GalpNAcA(alpha 1 leads to 3)BacpNAc2(alpha 1 leads to. The parent lipopolysaccharide is a mixture of S, R, and SR species, and its high phosphorus content is partly due to the presence of triphosphate residues, as found for other lipopolysaccharides from P. aeruginosa. In addition to phosphorus, heptose, a 3-deoxyoctulosonic acid, and amide-bound alanine, the core oligosaccharide contains glucose, rhamnose, and galactosamine (molar proportions 3:1:1). The rhamnose and part of the glucose are present as unsubstituted pyranoside residues: other glucose residues are 6-substituted.

References

Sep 1, 1975·The Biochemical Journal·S G Wilkinson, A P Welbourn
Feb 16, 1976·European Journal of Biochemistry·W Gromska, H Mayer
Mar 17, 1975·European Journal of Biochemistry·S G Wilkinson, L Galbrath
Sep 1, 1975·Antimicrobial Agents and Chemotherapy·D I SmithR W Hedges
Oct 15, 1975·European Journal of Biochemistry·I R Chester, P M Meadow
Feb 6, 1981·Biochimica Et Biophysica Acta·D Horton, D A Riley
Nov 1, 1981·Journal of Virology·K F Jarrell, A M Kropinski
Jun 1, 1982·Carbohydrate Research·R J DoyleP H Carstens
Nov 16, 1981·Carbohydrate Research·P Branefors-HelanderP Unger

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Citations

Dec 31, 2002·American Journal of Physiology. Lung Cellular and Molecular Physiology·Rebecca E Oberley, Jeanne M Snyder
May 1, 1990·Journal of Bacteriology·P MessnerU B Sleytr

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