The Loading of Luminescent Magnetic Nanocomposites Fe₃O₄@Polyaniline/Carbon Dots for Methotrexate and Its Release Behavior In Vitro.

Journal of Nanoscience and Nanotechnology
Yi WuShenghua Liao

Abstract

In the present study we developed novel luminescent magnetic nanocomposites termed Fe₃O₄@polyaniline/carbon dots. First, Fe₃O₄ magnetic nanoparticles were prepared by the coprecipitation method. The nanoparticles were then coated with polyaniline using the in situ growth method to form Fe₃O₄@polyaniline nanohybrids, which were endowed with amino functional groups on the surface and avoided the aggregation of Fe₃O₄ nanoparticles. The X-ray diffraction pattern demonstrated that the crystalline phase of the Fe₃O₄ nanoparticles was an inverse spinel structure and was not changed in the Fe₃O₄@polyaniline nanohybrids. The saturation magnetization and the coercive force of the as-prepared Fe₃O₄@polyaniline nanohybrids measured by a vibrating sample magnetizer were 63.7 emu·g-1 and zero respectively, which indicated that the Fe₃O₄@polyaniline nanohybrids exhibited excellent superparamagnetism. The Fe₃O₄@polyaniline nanohybrids were conjugated with carbon dots, prepared from orange juice, via the amide bond between the amino groups on the surface of the Fe₃O₄@polyaniline nanohybrids and the carboxyl groups on the surface of carbon dots. The obtained luminescent magnetic nanocomposites Fe₃O₄@polyaniline/carbon dots showed good photolumin...Continue Reading

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