PMID: 9428482Jan 15, 1998Paper

The long term efficacy of combined transcatheter arterial embolization and percutaneous ethanol injection in the treatment of patients with large hepatocellular carcinoma and cirrhosis

Cancer
K TanakaH Sekihara

Abstract

The long term efficacy of combination therapy with transcatheter arterial embolization (TAE) followed by percutaneous ethanol injection (PEI) was studied in patients with large primary hepatocellular carcinoma (HCC) tumors and cirrhosis. The series included 83 patients with large unresectable HCC lesions, the largest of which was greater than 3 cm in largest dimension. Fifty-five had a solitary lesion and 28 had multiple (2 or 3) lesions. All patients were treated with both TAE and PEI and their survival rates were determined. The 3-, 5-, and 7-year calculated survival rates for the patients were be 68%, 35%, and 14%, respectively. The number of lesions (solitary vs. multiple), the stage of cirrhosis (Child's Class A vs. Class B or C), and the size of the largest lesion (3-5 cm in largest dimension compared with > 5 cm) significantly affected the survival rate (P < 0.05 to P < 0.01, log rank test). The 3-, 5-, and 7-year survival rates of the Child's Class A patients who had a 3-5 cm solitary lesion (n = 22) were 100%, 75%, and 27%, respectively. The Cox proportional hazards model showed the stage of cirrhosis and size of the largest lesion to be independently associated with survival. No serious complications occurred during o...Continue Reading

References

Sep 1, 1976·Radiology·H M GoldsteinC Gianturco
Aug 1, 1992·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·R VilanaJ Rodés
Jan 1, 1992·Cancer Chemotherapy and Pharmacology·Y HasuikeS Okamoto
Nov 1, 1990·Journal of Gastroenterology and Hepatology·M EbaraY Kondo
Nov 1, 1987·AJR. American Journal of Roentgenology·S ShiinaR Takanashi
Nov 1, 1987·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·K OhnishiS Sugita
May 1, 1993·AJR. American Journal of Roentgenology·S ShiinaA Terano
Nov 1, 1993·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·A CastellsJ Rodés

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Citations

May 12, 2009·International Journal of Radiation Oncology, Biology, Physics·Shinji SugaharaKoichi Tokuuye
Nov 6, 2007·Techniques in Vascular and Interventional Radiology·Timothy W I Clark
Oct 2, 2002·Journal of Vascular and Interventional Radiology : JVIR·Timothy W I Clark, Michael C Soulen
Nov 29, 2002·Seminars in Roentgenology·Douglas E Ramsey, Jean-Francois H Geschwind
Nov 30, 2004·Liver International : Official Journal of the International Association for the Study of the Liver·Masatoshi AkamatsuMasao Omata
Jun 17, 2009·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Hiroyuki KirikoshiAtsushi Nakajima
Jun 6, 2003·Alimentary Pharmacology & Therapeutics·S GaianiL Bolondi
Mar 15, 2008·Liver International : Official Journal of the International Association for the Study of the Liver·Reeta VeteläinenThomas M van Gulik
Dec 4, 2003·Expert Opinion on Pharmacotherapy·John F PerryGeoffrey W McCaughan
Feb 27, 1999·International Journal of Cancer. Journal International Du Cancer·S MoritaM Monden
Apr 14, 2005·European Journal of Gastroenterology & Hepatology·Josep M Llovet, Margarita Sala
Nov 8, 2005·World Journal of Gastroenterology : WJG·Gerhild BeckerHans-Peter Allgaier
Jun 29, 2010·Annals of Oncology : Official Journal of the European Society for Medical Oncology·S JelicUNKNOWN ESMO Guidelines Working Group
Mar 11, 2017·The Cochrane Database of Systematic Reviews·Davide RoccarinaKurinchi Selvan Gurusamy
Dec 2, 2000·Journal of Gastroenterology and Hepatology·Z Y Tang
Sep 13, 2011·Journal of Cancer Research and Clinical Oncology·Jun Qian
Sep 10, 2002·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Kazuhito ShiratoKatsuaki Tanaka
May 29, 2015·World Journal of Hepatology·Giovan Giuseppe Di Costanzo, Raffaella Tortora
Dec 1, 2010·Journal of Radiation Research·Sook In ChungKwang-Hyub Han
Oct 21, 2020·Soft Matter·Tingyuan TanYi Zhang

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