Jun 1, 1993

The long-term outcome after surgical treatment of dorsally exophytic brain-stem gliomas

Journal of Neurosurgery
I F PollackL Becker

Abstract

Dorsally exophytic brain-stem gliomas represent a distinctive subgroup of pediatric brain-stem neoplasms that are amenable to radical excision because of their benign histology and growth characteristics. However, their attachment to the floor of the fourth ventricle invariably precludes complete tumor excision. The long-term behavior of the residual tumor remains a subject of concern. To address this issue, the authors reviewed their experience with 18 dorsally exophytic brain-stem gliomas treated between 1974 and 1990. At operation, the tumors filled the fourth ventricle, fungating out of a broad-based area of the dorsal brain stem. The exophytic tumor was resected, but no attempt was made to remove tumor from the brain stem. Histological examination showed that 16 of the tumors were grade I or II astrocytomas, one was a ganglioglioma, and one was an otherwise benign-appearing glioma with several foci of anaplasia that was classified as a grade III astrocytoma. The latter patient was one of only two in the series to receive postoperative radiation therapy; both cases so treated have no evidence of disease on follow-up imaging studies 61 and 135 months postoperatively. One other child who had stable disease postoperatively die...Continue Reading

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  • Citations59

Citations

Mentioned in this Paper

Neoplasm Recurrence, Local
Ganglioglioma
Neoplasms
Blind Vision
Anaplasia
Postoperative Procedures
Mixed Gliomas
Tomography, X-Ray Computerized Axial
Neoplasm, Residual
Glioma

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