The long-term prognostic value of the resting and postexercise ankle-brachial index

Archives of Internal Medicine
Harm H H FeringaDon Poldermans

Abstract

Peripheral arterial disease is associated with a high incidence of cardiovascular mortality. Peripheral arterial disease can be detected by using the ankle-brachial index (ABI). This study assessed the prognostic value of the postexercise ABI in addition to the resting ABI on long-term mortality in patients with suspected peripheral arterial disease. In this prospective cohort study of 3209 patients (mean +/- SD age, 63 +/- 12 years; 71.1% male), resting and postexercise ABI values were measured and a reduction of postexercise ABI over baseline resting readings was calculated. The mean follow-up was 8 years (interquartile range, 4-11 years). During follow-up, 1321 patients (41.2%) died. After adjusting for clinical risk factors, lower resting ABI values (hazard ratio per 0.10 lower ABI, 1.08; 95% confidence interval [CI], 1.06-1.10), lower postexercise ABI values (hazard ratio per 0.10 lower ABI, 1.09; 95% CI, 1.08-1.11), and higher reductions of ABI values over baseline readings (hazard ratio per 10% lower ABI, 1.12; 95% CI, 1.09-1.14) were significantly associated with a higher incidence of mortality. In patients with a normal resting ABI (n = 789), a reduction of the postexercise ABI by 6% to 24%, 25% to 55%, and greater tha...Continue Reading

Citations

Dec 24, 2008·Cardiovascular and Interventional Radiology·Mies A KortewegOtto E H Elgersma
Sep 8, 2010·Journal of the American Medical Informatics Association : JAMIA·Iftikhar J KulloChristopher G Chute
Jul 17, 2008·Journal of General Internal Medicine·Kim G SmolderenJohan Denollet
Oct 24, 2009·Vascular Health and Risk Management·Mo Al-QaisiSam Kaddoura
Feb 10, 2009·Medical & Biological Engineering & Computing·Fuyou LiangHao Liu
Mar 29, 2008·Metabolic Syndrome and Related Disorders·Catherine Y CampbellRoger S Blumenthal
Oct 1, 2011·Revista Portuguesa De Cardiologia : Orgão Oficial Da Sociedade Portuguesa De Cardiologia = Portuguese Journal of Cardiology : an Official Journal of the Portuguese Society of Cardiology·Evangelista Rocha
Jan 21, 2011·The American Journal of Cardiology·Mobeen A SheikhJohn R Bartholomew
Apr 26, 2015·Journal of Vascular Surgery·Serdal UgurluHasan Yazici
Aug 22, 2015·JACC. Cardiovascular Interventions·Tarek A HammadMehdi H Shishehbor
Jun 20, 2013·Blood Pressure·UNKNOWN Task Force for the management of arterial hypertension of the European Society of Hypertension, UNKNOWN Task Force for the management of arterial hypertension of the European Society of Cardiology
Jan 8, 2008·Journal of Vascular Surgery·Andrew W GardnerDonald E Parker
Oct 9, 2007·Journal of Vascular Surgery·Andrew W GardnerSteve M Blevins
May 8, 2007·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·H H H FeringaD Poldermans
Apr 9, 2008·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·J MerinoA Clarà
Jul 10, 2009·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·I I de LiefdeD Poldermans
Apr 3, 2007·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·O SchoutenD Poldermans
May 17, 2008·Journal of the American College of Cardiology·Raul J GuzmanXiao Qin
Mar 21, 2009·Journal of the American College of Cardiology·Heather L Gornik
Oct 8, 2014·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Hirofumi HiokiUichi Ikeda
Nov 6, 2007·European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology·Ian GrahamUNKNOWN European Atherosclerosis Society (EAS)
Apr 1, 2011·European Journal of Preventive Cardiology·Inge I de LiefdeDon Poldermans
Feb 6, 2016·American Journal of Men's Health·Omer A RaheemTung-Chin Hsieh
Nov 26, 2009·The Journal of International Medical Research·Andrej Kravos, K Bubnic-Sotosek
Oct 20, 2009·European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology·Inge I de LiefdeDon Poldermans
May 18, 2007·Journal of Human Hypertension·V J Karthikeyan, G Y H Lip

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antihypertensive Agents: Mechanisms of Action

Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.