The longitudinal association of vitamin D serum concentrations & adiposity phenotype

The Journal of Steroid Biochemistry and Molecular Biology
Aziza Jamal-AllialKatherine L Tucker

Abstract

Several cross-sectional studies have reported on the association between serum 25-hydroxy vitamin D concentrations (25(OH)D) and body mass index (BMI). We examined the longitudinal effect of BMI on serum 25(OH)D concentrations among 866 Puerto Rican adults living in the Greater Boston area: 246 men and 620 women, aged 45-75 years at baseline and 2 year. Our analyses showed negative correlations at two time points between BMI and serum 25(OH)D concentrations. The multivariate analysis showed that when predicting the change of serum 25(OH)D concentrations, baseline-BMI had significant inverse association (P<0.04) controlling for age, sex, and baseline-BMI. This association remained significant after adjusting for vitamin D supplement use, smoking, miles walked/day and alcohol intake (P<0.01). In conclusion, the major findings of the present study are obesity (1) was inversely associated with 25(OH)D at baseline; (2) with the change in serum 25(OH)D at 2-year in this population of older Puerto Rican adults living in the Boston area. This article is part of a Special Issue entitled '16th Vitamin D Workshop'.

Associated Clinical Trials

Nov 1, 2010·Katherine Tucker

References

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Citations

Nov 13, 2014·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·T L CostaV C Borba
Aug 20, 2014·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·María Agustina AlonsoFernando Santos
Dec 3, 2014·PloS One·Nina O NielsenPeter Bjerregaard
Dec 24, 2014·Multiple Sclerosis : Clinical and Laboratory Research·Julie H LaursenAnnette Oturai
Nov 2, 2014·The Proceedings of the Nutrition Society·L Kirsty Pourshahidi
Mar 27, 2018·Biological Reviews of the Cambridge Philosophical Society·Douglas B Kell, Etheresia Pretorius

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