The longitudinal relation of stress during the menopausal transition to fibrinogen concentrations: results from the Study of Women's Health Across the Nation

Menopause : the Journal of the North American Menopause Society
April M FalconiImke Janssen

Abstract

Life course theory suggests that exposures during critical or sensitive periods have particularly profound effects on health. Most research on this subject has focused on the occurrence of such windows early in life. We investigated whether perimenopause, a period of dramatic neuroendocrine changes at midlife, represents a sensitive period for response to stress by evaluating the relation of perceived stress to fibrinogen, a biomarker for inflammation. The study sample was composed of participants in the Study of Women's Health Across the Nation, a longitudinal study on women's health during the menopausal transition (n = 3,287). We fitted linear mixed effects models to estimate the longitudinal relationship between stress and menopausal stage and the association between stress and fibrinogen over the menopausal transition. Women in early and late perimenopause reported perceiving higher levels of stress than premenopausal women (P < 0.05), adjusted for confounding variables. This increased perception of stress during perimenopause, however, was unrelated to changes in fibrinogen. Although neuroendocrine changes during the menopausal transition may exacerbate the negative health effects of stress, the findings of this study do ...Continue Reading

References

Jul 1, 1992·Annals of Epidemiology·W B KannelA J Belanger
Jan 1, 1990·Annals of the New York Academy of Sciences·S Ballinger
Jan 13, 2000·Archives of General Psychiatry·J M CyranowskiM K Shear
Jul 27, 2000·Medicine and Science in Sports and Exercise·B E AinsworthK Jackson
Apr 27, 2001·American Journal of Epidemiology·E B GoldJ Skurnick
May 23, 2002·Recent Progress in Hormone Research·Henry G BurgerLorraine Dennerstein
Oct 24, 2002·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Pekka JousilahtiTimo Palosuo
Nov 26, 2002·European Heart Journal·T Theorell
Aug 14, 2003·American Journal of Epidemiology·Joyce T BrombergerAdriana Cordal
Sep 23, 2003·QJM : Monthly Journal of the Association of Physicians·S Kamath, G Y H Lip
Feb 14, 2004·Archives of Women's Mental Health·P J SchmidtM A Danaceau
Dec 3, 2004·Proceedings of the National Academy of Sciences of the United States of America·Elissa S EpelRichard M Cawthon
Mar 12, 2005·Annual Review of Public Health·John Lynch, George Davey Smith
Jul 16, 2005·Stress : the International Journal on the Biology of Stress·Noreen GoldmanMaxine Weinstein
Feb 9, 2006·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Paolo Pauletto, Marcello Rattazzi
Mar 3, 2007·Journal of Affective Disorders·Joyce T BrombergerJohn F Randolph
Aug 25, 2007·Annual Review of Clinical Psychology·Constance Hammen
Dec 6, 2007·Expert Review of Neurotherapeutics·Jeanne Leventhal AlexanderGregg Richardson
Oct 14, 2009·Neuroscience and Biobehavioral Reviews·Robert-Paul JusterSonia J Lupien
Jul 22, 2010·The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences·Jennifer R PiazzaLaura C Klein
Jan 5, 2011·Frontiers in Bioscience (Scholar Edition)·Jerilynn C Prior, Christine L Hitchcock
Mar 23, 2011·Steroids·Laura Butler, Nanette Santoro
Mar 29, 2011·Rheumatology·Terence RooneyCarl Grunfeld
May 18, 2011·Indian Journal of Endocrinology and Metabolism·Salam Ranabir, K Reetu
Sep 15, 2012·The American Journal of Cardiology·Safiya RichardsonDonald Edmondson
Jul 23, 2013·Psychosomatic Medicine·Lisa M ChristianJay D Iams
May 17, 2014·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Elissa S Epel, Gordon J Lithgow

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Citations

Dec 1, 2017·Menopause : the Journal of the North American Menopause Society·Lisa Taylor-SwansonNancy F Woods
Aug 25, 2020·Journal of Women & Aging·Ruba M JaberSaif Aldeen AlRyalat
Aug 6, 2019·BioMed Research International·Noof Abdullah ShaifInsop Shim
Apr 29, 2021·The European Journal of Neuroscience·Marta BalogMarija Heffer

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