PMID: 11926642Apr 3, 2002Paper

The loss rates for invasive prenatal testing in a specialised obstetric ultrasound practice

The Australian & New Zealand Journal of Obstetrics & Gynaecology
Fergus ScottDavid Edelman

Abstract

To establish the spontaneous miscarriage rate and compare it with the procedure related miscarriage rate for amniocentesis and chorionic villus sampling (CVS) by experienced operators. Retrospective audit over a two-year period of all patients having a consultation for prenatal diagnosis before 12 weeks gestation. A specialised obstetric and gynaecological ultrasound practice. A total of 2366 patients, mostly over 35 years of age. Between 1 July 1995 and 30 June 1997, all patients having a prenatal consultation decided between amniocentesis, CVS or no invasive testing. The CVS was performed either transabdominally or transcervically, depending on the position of the uterus and placenta. Delivery, termination of pregnancy for chromosomal abnormality or miscarriage. Over the two-year period, 2366 patients had a prenatal consultation and outcome data were available for all but 53 patients. After consultation, 346 patients decided not to have any prenatal testing and 29 (8.4%) of these had a spontaneous miscarriage. Amniocentesis was requested by 839 patients; however 10 miscarried before the scheduled procedure. After the amniocentesis, there were 13 terminations for chromosomal abnormality and three miscarriages. CVS was requeste...Continue Reading

References

Aug 1, 1991·The Australian & New Zealand Journal of Obstetrics & Gynaecology·D M WassT A Saville
Jul 23, 1998·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·A P SoukaK H Nicolaides

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Citations

Jan 17, 2008·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Deborah A DriscollUNKNOWN Professional Practice and Guidelines Committee
Jun 2, 2011·Journal of Perinatal Medicine·Michael TchirikovHeinz Koelbl
Apr 28, 2006·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Tou Choong Chang
Jan 27, 2005·American Journal of Obstetrics and Gynecology·Philip R WyattTianhua Huang
Jun 30, 2016·The Journal of Obstetrics and Gynaecology Research·Mohan S KamathKorula George
Oct 2, 2008·Obstetrics and Gynecology·Anthony O OdiboJames P Crane
Sep 2, 2006·Obstetrics and Gynecology·Aaron B CaugheyMary E Norton
Sep 4, 2007·Obstetrics and Gynecology·Faris Mujezinovic, Zarko Alfirevic
Jan 24, 2007·Prenatal Diagnosis·Vincenzo MazzaAnnibale Volpe
Apr 18, 2008·Fetal Diagnosis and Therapy·P GaudryF Lewin

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