The Low Fall as a Surrogate Marker of Frailty Predicts Long-Term Mortality in Older Trauma Patients

PloS One
Ting Hway WongDennis Chuen Chai Seow

Abstract

Frailty is associated with adverse outcomes including disability, mortality and risk of falls. Trauma registries capture a broad range of injuries. However, frail patients who fall comprise a large proportion of the injuries occurring in ageing populations and are likely to have different outcomes compared to non-frail injured patients. The effect of frail fallers on mortality is under-explored but potentially significant. Currently, many trauma registries define low falls as less than three metres, a height that is likely to include non-frailty falls. We hypothesized that the low fall from less than 0.5 metres, including same-level falls, is a surrogate marker of frailty and predicts long-term mortality in older trauma patients. Using data from the Singapore National Trauma Registry, 2011-2013, matched till September 2014 to the death registry, we analysed adults aged over 45 admitted via the emergency department in public hospitals sustaining blunt injuries with an injury severity score (ISS) of 9 or more, excluding isolated hip fractures from same-level falls in the over 65. Patients injured by a low fall were compared to patients injured by high fall and other blunt mechanisms. Logistic regression was used to analyze 12-mon...Continue Reading

References

Apr 11, 1990·JAMA : the Journal of the American Medical Association·J A MorrisS L Edelstein
May 1, 1990·The Journal of Trauma·H R ChampionS Schwaitzberg
May 1, 1989·The Journal of Trauma·H R ChampionM E Flanagan
May 3, 1995·JAMA : the Journal of the American Medical Association·M E TinettiJ T Doucette
Jan 15, 1999·Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention·D SleetC Branche
Mar 17, 2001·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·L P FriedUNKNOWN Cardiovascular Health Study Collaborative Research Group
Feb 13, 2003·The Journal of Trauma·David G JacobsUNKNOWN EAST Practice Management Guidelines Work Group
Dec 16, 2003·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Lois E WehrenJay Magaziner
Jan 26, 2005·Journal of the American Geriatrics Society·Martine T E PutsDorly J H Deeg
Jan 27, 2006·The New England Journal of Medicine·Ellen J MacKenzieDaniel O Scharfstein
Nov 14, 2006·The Journal of Trauma·William F FallonJames Campbell
Apr 2, 2008·The Journal of Bone and Joint Surgery. British Volume·G HoltA Gregori
Jun 4, 2008·Annals of Surgery·Turner OslerAndrew Dick
Aug 5, 2008·Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention·G DavieJ Langley
Sep 23, 2008·The Journal of Surgical Research·Adil H HaiderDavid T Efron
Jan 1, 2009·BMC Health Services Research·Ramon DanielsWim van den Heuvel
Apr 28, 2009·American Journal of Surgery·Ryan LehmannMatthew Martin
May 8, 2009·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·B AbrahamsenC Cooper
May 29, 2009·Annals of Surgery·Laurent G GlanceAndrew W Dick
Nov 10, 2009·Injury·Nerida Butcher, Zsolt J Balogh
Feb 18, 2010·The American Journal of Emergency Medicine·Jeffrey M CaterinoHoward A Werman
Jul 14, 2010·Annals of Surgery·Hilaire J ThompsonEllen J Mackenzie
Dec 17, 2010·Clinical Orthopaedics and Related Research·Robert S Sterling
Dec 28, 2010·Journal of the American College of Surgeons·Madhukar S PatelDavid B Hoyt
May 4, 2011·The Journal of Trauma·Noura LabibKosar Khwaja
Jun 28, 2011·The Journal of Surgical Research·Tolulope A OyetunjiAdil H Haider
Nov 19, 2011·Journal of the American Geriatrics Society·Shelley A SternbergA Mark Clarfield
Apr 11, 2012·International Journal of Injury Control and Safety Promotion·Wu-Chien ChienChia-Hsin Lin
Apr 24, 2012·Age and Ageing·Roman Romero-Ortuno, Rose Anne Kenny
Oct 2, 2012·Surgery·Nicholas W GoodmansonGary T Marshall
Oct 31, 2012·Annals of Surgery·Magda LenartowiczCamilla L Wong
Dec 12, 2012·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·G C-H KohW-P Koh
Sep 21, 2013·Critical Care : the Official Journal of the Critical Care Forum·Lesley L MoiseyUNKNOWN Nutrition and Rehabilitation Investigators Consortium (NUTRIC)
Oct 12, 2013·Prehospital Emergency Care : Official Journal of the National Association of EMS Physicians and the National Association of State EMS Directors·Kristy Gonzalez MorgantiArthur L Kellermann
Nov 29, 2013·JAMA Surgery·Areti TillouLillian Min
Dec 3, 2013·Critical Care : the Official Journal of the Critical Care Forum·Carsten SchoenebergSven Lendemans
Jan 24, 2014·JAMA Surgery·Kazuhide MatsushimaDavid I Soybel
Jan 25, 2014·The Journal of Trauma and Acute Care Surgery·Patricia Ayoung-CheeRonald V Maier
May 13, 2014·American Journal of Surgery·Rondi GelbardDemetrios Demetriades

❮ Previous
Next ❯

Citations

Dec 2, 2017·Journal of Forensic Sciences·Samantha K RowbothamVictoria Francis
Jan 11, 2018·Geriatric Orthopaedic Surgery & Rehabilitation·Mei Teng WooTimo Jaakkola
Apr 18, 2018·Spine·Ville Niemi-NikkolaAki Vainionpää
Jul 23, 2020·European Journal of Trauma and Emergency Surgery : Official Publication of the European Trauma Society·André NohlUwe Hamsen
Apr 20, 2018·Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine·Ting Hway WongMarcus Eng Hock Ong
Dec 14, 2018·World Journal of Emergency Surgery : WJES·Aidan Lyanzhiang TanTing Hway Wong
Aug 5, 2019·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·S K GratzaH A Bischoff-Ferrari
May 8, 2020·PloS One·Alicia Padrón-MonederoJavier Damián
Jun 18, 2020·International Journal of Environmental Research and Public Health·Ting-Min HsiehChing-Hua Hsieh
Mar 7, 2020·Journal of Trauma Nursing : the Official Journal of the Society of Trauma Nurses·Sergio Dias MartuchiLilia de Souza Nogueira
Apr 27, 2021·European Journal of Trauma and Emergency Surgery : Official Publication of the European Trauma Society·Kei Ching Kevin HungColin Alexander Graham
Oct 14, 2018·Journal of the American Medical Directors Association·Ting Hway WongChek Hooi Wong
Feb 25, 2019·Journal of the American Medical Directors Association·Wycliffe E WeiTing Hway Wong

❮ Previous
Next ❯

Methods Mentioned

BETA
ISS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The American Journal of Emergency Medicine
Shan W LiuKalpana N Shankar
Journal of Emergencies, Trauma, and Shock
Jaspal SinghAshish Gupta
© 2021 Meta ULC. All rights reserved