PMID: 45440Jun 1, 1979

The lower esophageal sphincter in gastroesophageal reflux in children

Journal of Clinical Gastroenterology
J J HerbstS G Jolley


Esophageal function was evaluated in 51 children less than 2 years of age with radiologic evidence of gastroesophageal reflux. Detection of an acid esophageal pH was a sensitive measure of gastroesophageal reflux. Lower esophageal sphincter pressures were greater in reflux patients with respiratory symptoms (18.0 +/- 1.4 mm Hg) than in reflux patients without respiratory symptoms (9.5 +/- 1.0 mm Hg). The intra-abdominal segment of the lower esophageal sphincter was shorter in patients with reflux than in controls (0.51 +/- 0.05 cm vs. 0.75 +/- 0.08 cm). It was also shorter in patients requiring surgical therapy (0.34 +/- 0.05 cm) than in those responding to medical therapy (0.63 +/- 0.07 cm).


Jul 1, 1990·Journal of Clinical Ultrasound : JCU·S J WestraC R Staalman
Sep 1, 1985·European Journal of Pediatrics·T R Weihrauch
Dec 1, 1979·American Journal of Surgery·S G JolleyV R Condon
Feb 1, 1996·Pediatric Clinics of North America·A C Hillemeier
Oct 1, 1984·The Australian and New Zealand Journal of Surgery·D G JohnsonJ J Herbst

Related Concepts

Respiratory Tract Diseases
Gastroesophageal Reflux Disease
Hydrogen-Ion Concentration
Esophagogastric Junction

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