The lower vitamin C plasma concentrations in elderly men compared with elderly women can partly be attributed to a volumetric dilution effect due to differences in fat-free mass

The British Journal of Nutrition
Alexandra Jungert, Monika Neuhäuser-Berthold

Abstract

Women show higher vitamin C plasma concentrations than men, but the reasons for this observation still require elucidation. The objective of the present study was to investigate whether sex differences in vitamin C plasma concentrations are present in elderly subjects and whether these differences are due to sex-specific lifestyles, total antioxidant status (TAOS) and/or body composition. Fasting plasma concentrations of vitamin C were assessed by photometric detection in a cross-sectional study of 181 women and eighty-nine men aged 62-92 years. Body composition was determined by bioelectrical impedance analysis. Vitamin C intake was assessed with a 3 d estimated dietary record. Stepwise multiple regression analyses were performed to investigate whether sex is an independent predictor of vitamin C plasma concentrations by controlling for age, vitamin C intake, lifestyle factors, TAOS and body composition. Women showed higher vitamin C plasma concentrations than men (76 v. 62 μmol/l, P< 0·0001). In the multiple regression analysis, male sex was a negative predictor of vitamin C plasma concentrations (β = -0·214), as long as absolute fat-free mass (FFM) was not considered as a confounder. When absolute FFM was included, sex was n...Continue Reading

References

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Feb 6, 2003·Journal of the American College of Nutrition·Sebastian J PadayattyMark Levine
Sep 25, 2008·Journal of Public Health·Annhild MosdølEric J Brunner
Jul 15, 2009·American Journal of Epidemiology·Leah CahillAhmed El-Sohemy
May 23, 2012·Nutrition & Metabolism·Alexandra JungertMonika Neuhäuser-Berthold

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Citations

Aug 15, 2018·International Journal for Quality in Health Care : Journal of the International Society for Quality in Health Care·Kirill KosilovAlexandra Prokofyeva
May 23, 2020·Nutritional Neuroscience·Puja AgarwalMartha C Morris
Apr 1, 2020·Critical Reviews in Food Science and Nutrition·Anitra C Carr, Jens Lykkesfeldt

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