The LungVision navigational platform for peripheral lung nodule biopsy and the added value of cryobiopsy.

Thoracic Cancer
Barak PertzovMordechai Reuven Kramer

Abstract

The LungVision system is a novel augmented-fluoroscopy-based real-time navigation and guidance technology for bronchoscopy that can be integrated with any standard biopsy tool, including the cryoprobe, to enable real-time visualization and localization of pulmonary nodules. To evaluate the diagnostic yield and safety among patients undergoing peripheral pulmonary nodule biopsy with the LungVision system. This prospective, single-center study was conducted at Rabin Medical Center in Israel. All patients that underwent peripheral pulmonary nodule biopsy with the LungVision system from January 2016 to August 2020 were included. All procedures were performed under moderate sedation. The primary outcome was tissue diagnosis by either identification of malignant cells or benign diagnosis. Secondary outcomes were safety and the added value of cryobiopsy. Sixty-three procedures were performed during the study period. Median lesion size (interquartile range) was 25.0 mm (18-28 mm). The diagnostic yield overall was 27/33 (81.8%) and for lesions smaller than 20 mm was 13/18 (72.2%). In nine cases the transbronchial cryobiopsy showed tissue with malignant cells that were not found in any other biopsy material taken with other sampling tool...Continue Reading

References

Feb 28, 2009·Respiration; International Review of Thoracic Diseases·Alexander BabiakMartin Hetzel
Aug 20, 2011·The European Respiratory Journal·J HetzelM Hetzel
Oct 8, 2011·Chest·Jessica S Wang MemoliGerard A Silvestri
Apr 23, 2013·American Journal of Respiratory and Critical Care Medicine·Fumihiro AsanoSatoshi Morita
Aug 1, 2013·The European Respiratory Journal·Maren SchuhmannRalf Eberhardt
Jan 10, 2014·Respiration; International Review of Thoracic Diseases·Gregoire GexPaola M Soccal
Feb 14, 2014·The Clinical Respiratory Journal·Oren Fruchter, Mordechai R Kramer
Nov 18, 2014·Respiration; International Review of Thoracic Diseases·Fumihiro AsanoFelix J F Herth
May 23, 2015·Respiration; International Review of Thoracic Diseases·Evgeni GershmanMordechai R Kramer
Jun 18, 2015·Thorax·M E J CallisterUNKNOWN British Thoracic Society Standards of Care Committee
Aug 19, 2015·American Journal of Respiratory and Critical Care Medicine·Christopher G SlatoreUNKNOWN ATS Ad Hoc Committee on Setting a Research Framework for Pulmonary Nodule Evaluation
Sep 15, 2015·American Journal of Respiratory and Critical Care Medicine·David E OstUNKNOWN AQuIRE Bronchoscopy Registry
Mar 24, 2016·Respiration; International Review of Thoracic Diseases·Dominik HarzheimFelix J F Herth
May 14, 2016·The European Respiratory Journal·Michele MondoniStefano Centanni
May 22, 2017·The Annals of Thoracic Surgery·Mark R BowlingCarlos J Anciano
May 16, 2018·Journal of Bronchology & Interventional Pulmonology·José R Rojas-SolanoMichael Machuzak
Jan 25, 2019·Journal of Bronchology & Interventional Pulmonology·Ramsy AbdelghaniFayez Kheir
Oct 2, 2019·Anticancer Research·Shingo NasuTomonori Hirashima
Nov 7, 2019·General Thoracic and Cardiovascular Surgery·Tsukasa IshiwataKazuhiro Yasufuku
Feb 27, 2020·Respiration; International Review of Thoracic Diseases·Jürgen HetzelVenerino Poletti

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