The maintenance of single-locus polymorphism by maternal selection

G3 : Genes - Genomes - Genetics
Hamish G Spencer, Kai X Chiew

Abstract

Population geneticists have long been interested in the ability of natural selection to maintain the levels of standing variation observed in natural populations. Here, we study the polymorphism-maintaining properties of maternal selection, in which the fitness of an individual is a function of its own and its mother's genotype. Using a model proposed by Gavrilets, we first estimate the proportion of parameter/state space that preserves allelic variation, before investigating the construction of polymorphism over time through the joint action of mutation and selection. These two methods, the "parameter-space" and "constructionist" approaches, respectively, enable us to draw some general conclusions. We argue that, even though the proportion of parameter-state space allowing multiallele polymorphism is greater under maternal selection than under the standard model of constant viability selection, the former is, in fact, less likely to maintain large numbers of alleles. Nevertheless, variation that is balanced by maternal selection is likely to show elements of heterozygous advantage and be resistant to depletion by genetic drift. We observe that the population mean fitness frequently decreases after the successful invasion of a ...Continue Reading

References

May 24, 2001·Proceedings of the National Academy of Sciences of the United States of America·E Nevo
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Feb 28, 2008·Evolution; International Journal of Organic Evolution·Matthew W Hahn
Jun 20, 2008·Genetics·Bastiaan StarHamish G Spencer
Mar 28, 2009·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Jason B Wolf, Michael J Wade
Jul 10, 2010·Journal of Mathematical Biology·Su-Chan Park, Joachim Krug
Mar 2, 2012·Genetics·Jason Wolf, James M Cheverud
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Jul 16, 2013·Genetics·Meredith V Trotter, Hamish G Spencer
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Mar 1, 1977·Evolution; International Journal of Organic Evolution·John H Gillespie

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Citations

Mar 13, 2016·Evolution; International Journal of Organic Evolution·Jason B Wolf, Michael J Wade
Sep 23, 2016·G3 : Genes - Genomes - Genetics·Hamish G Spencer, Cuilodair Mitchell

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