PMID: 8583613Mar 1, 1996Paper

The management and outcome of stage IAE nonHodgkin's lymphoma of the testis

The Journal of Urology
A ZietmanF G McGovern

Abstract

The initial management of stage I nonHodgkin's lymphoma of the testis is by orchiectomy but the role and efficacy of adjuvant strategies are uncertain. We reviewed cases of lymphoma at our institution to determine whether adjuvant treatment was beneficial. A retrospective review of outcome was conducted on 26 patients who presented to our institution. Median followup for the group was 54 months. Kaplan-Meier actuarial analyses were performed on the entire group and subsets. RESULTS; Actuarial 5 and 10-year overall survival rates were 79% and 63% and relapse-free survival rates were 61% and 46%, respectively. In patients who received adjuvant combination chemotherapy the 5-year relapse-free survival rate improved (75% versus 50%) but effect did not achieve statistical significance and was lost by 10 years. No relapse-free survival advantage was noted for patients receiving adjuvant irradiation to the pelvic and para-aortic nodes. Patients who did not receive irradiation remained free of isolated relapses in the pelvic or para-aortic regions. These data lend support to the use of adjuvant chemotherapy but do not support a role for adjuvant nodal irradiation.

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Citations

Apr 8, 1999·Cancer·L S FinnK E Salhany
May 15, 2010·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·Georgios Koukourakis, Vassilios Kouloulias
Feb 19, 2002·International Journal of Radiation Oncology, Biology, Physics·Abderrahim ZouhairUNKNOWN Rare Cancer Network
Jun 28, 2001·Leukemia & Lymphoma·M OkabeaT Miyagishima
Dec 31, 2002·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·E ZuccaUNKNOWN International Extranodal Lymphoma Study Group

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