The management of adolescents and young adults with cancer

Cancer Treatment Reviews
Nicola Hughes, Dan Stark

Abstract

Adolescents and Young Adults (AYA) with cancer are young people developing serious illness when at the interface between the responsibilities of paediatric and adult cancer services. Personally, they are in a period of transition both biologically and in major social roles (Sawyer et al., 2018) [1]. For these and other reasons they present a unique set of clinical challenges in their management. Over the last 20 years the requirement for specific services to address their needs has been identified and this has become a growing field of research. Despite this survival rates still lag behind those of children and older adults with cancer (Gatta et al., 2009) [2]. Why do AYA patients have worse outcomes? The observation is that the reason is multifactorial with path to diagnosis, unique cancer biology, uncertainty of treatment protocol, compliance issues and poor recruitment to clinical trials all playing a part. In this review we will discuss the unique challenges faced by healthcare professionals when managing AYA patients who are commonly and accurately described as being in an 'interface' position.

Citations

Mar 27, 2019·Journal of Adolescent and Young Adult Oncology·Tristan PettitRuth Spearing
Aug 15, 2019·Journal of Adolescent and Young Adult Oncology·Arthur DonyIsabelle Laure Ray-Coquard
Jan 15, 2020·Journal of Adolescent and Young Adult Oncology·Yu KeAlexandre Chan
Dec 5, 2019·Journal of Adolescent and Young Adult Oncology·Callie S Marshall, Allison Grimes
Jan 11, 2020·ANS. Advances in Nursing Science·Eunji Cho, Sharron L Docherty
Nov 30, 2018·European Journal of Cancer Care·Dan StarkRachel Taylor
Feb 20, 2019·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Kayla N LaRosaGwendolyn P Quinn
Nov 14, 2019·British Journal of Cancer·Klaus RostgaardLisa L Hjalgrim
Apr 1, 2020·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Nil A SchubertJan J Molenaar
Apr 30, 2021·JCO Oncology Practice·Sanyukta K Janardan, Daniel S Wechsler

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