PMID: 8937999Nov 1, 1996Paper

The management of common infections in ambulatory children

Pediatric Annals
W H Mason

Abstract

Antimicrobial therapy of infection in ambulatory children remains the cornerstone of the pediatrician's practice. Despite a cornucopia of newer antimicrobial agents, the older "tried and true" drugs continue to be favored based on their history of effectiveness, lack of toxicity, and low price. It also is clear that the widespread use of antimicrobial agents has contributed to the development of resistance. We must reevaluate our antimicrobial use so that we only treat infections likely to benefit from antimicrobials. Better diagnostic techniques should be developed for rapid and accurate identification of pathogens. Finally, alternative therapeutic strategies should be investigated, such as shorter courses of treatment or use of vaccines, to lessen the selective pressure on the microbial flora. To fail to meet this challenge will mean the more rapid transition into the "postantibiotic era".

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Citations

Jan 6, 2001·The Pediatric Infectious Disease Journal·D R Guay

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