The management of heart transplant recipients treated with cyclosporine in Ireland: monitoring of cyclosporine concentrations in blood

Irish Journal of Medical Science
F KyneA E Wood

Abstract

Thirty seven cardiac transplants have taken place at the National Cardiac Centre in Ireland since 1985. Data is presented on three still-surviving male patients aged 19 to 42 who received cardiac transplants in 1985 and 1986. Circulating levels of blood cyclosporine were measured by high pressure liquid chromatography and radioimmunoassay; plasma creatinine and bilirubin were also measured. In one of these patients the distribution of cyclosporine in blood was measured by high pressure liquid chromatography in a long term study. For all three patients cyclosporine levels in blood were compared with the daily dose of cyclosporine and biochemical and histopathological parameters.

References

Feb 1, 1985·Journal of Clinical Pathology·A Pomerance, P G Stovin
Mar 1, 1987·Annals of Clinical Biochemistry·S MaguireD UaConaill

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Citations

Apr 18, 2006·Irish Journal of Medical Science·D G HealyA E Wood

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