The Management of Lamellar Macular Holes: A Review

Journal of Ophthalmology
Ciprian DanielescuFlorian Balta

Abstract

This literature review aims to provide the retina specialist with answers to patient's questions related to the management of lamellar macular holes (LMHs). Most LMHs are stable over time, but 13-21% present an anatomic decline after 18-24 months of follow-up. Nineteen point five percent of the eyes may experience a visual acuity (VA) loss of more than 5 letters after 3 years. Many surgeons choose to perform surgery when there is significant metamorphopsia or documented decline in VA over time. The typical surgery is phacovitrectomy with the epiretinal membrane and the internal limiting membrane peeling in previously phakic eyes (41.9 to 85.3% of the eyes). In the eyes that remained phakic, cataract surgery was often necessary within the first year of follow-up (19.2 to 40% of eyes). After surgery, a VA gain was recorded in 63-94% of eyes, but some eyes (between 0 and 20%) suffered some VA loss. Progression to full-thickness macular hole may occur after surgery, and thus a second surgical intervention may be needed.

References

Nov 1, 1976·American Journal of Ophthalmology·A W Allen, J D Gass
Nov 9, 2004·American Journal of Ophthalmology·Belkacem HaouchineAlain Gaudric
Dec 27, 2005·American Journal of Ophthalmology·Mayumi HirakawaTaiji Sakamoto
Dec 31, 2005·Journal of Pediatric Ophthalmology and Strabismus·Alexander S IoannidisKen K Nischal
Feb 7, 2007·Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye·Gregg T Kokame, Keith G Tokuhara
Jun 19, 2007·Survey of Ophthalmology·Rukhsana G MirzaLee M Jampol
Dec 11, 2007·Ophthalmology·Bruce R GarretsonRamin Sarrafizadeh
Sep 4, 2008·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·P G TheodossiadisG P Theodossiadis
Jun 6, 2009·Retina·Noriyuki UnokiNagahisa Yoshimura
Jun 6, 2009·American Journal of Ophthalmology·Sofia AndroudiPeriklis D Brazitikos
Dec 17, 2009·Acta Ophthalmologica·Panagiotis G TheodossiadisGeorge P Theodossiadis
May 13, 2010·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Zofia MichalewskaJerzy Nawrocki
May 5, 2011·Retina·Heather Casparis, Etienne H Bovey
Oct 26, 2011·Investigative Ophthalmology & Visual Science·Barbara ParoliniGrazia Pertile
Dec 14, 2011·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Marta S FigueroaInés Contreras
May 10, 2012·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Ferdinando BottoniGiovanni Staurenghi
Oct 6, 2012·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Miriam García-FernándezCarmen González Castaño
Jan 15, 2013·American Journal of Ophthalmology·Alain GaudricPascale Massin
May 18, 2013·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Jen-Pin SunChang-Hao Yang
Oct 5, 2013·Clinical Ophthalmology·Huseyin SanisogluEbubekir Durmus
Jan 7, 2015·Ophthalmic Surgery, Lasers & Imaging Retina·Tatsuhiko SatoToshihide Ikeda
Jul 23, 2015·Retinal Cases & Brief Reports·Ryan B Rush, Sloan W Rush
Aug 28, 2015·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Tso-Ting LaiChung-May Yang
Feb 24, 2016·American Journal of Ophthalmology·Andrea GovettoJean-Pierre Hubschman
Nov 18, 2016·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Elena ZampedriRino Frisina
Nov 28, 2016·American Journal of Ophthalmology·Roberto dell'OmoCiro Costagliola
May 27, 2017·The British Journal of Ophthalmology·Denise ComperaFerdinando Bottoni
Oct 29, 2017·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·C Haritoglou, R G Schumann
Nov 8, 2017·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·D VogtR G Schumann
Mar 29, 2018·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·Marco Frederico MarquesJoão Figueira
Apr 7, 2018·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·K PurtskhvanidzeFelix Treumer
May 23, 2018·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Marco CoassinLuigi Fontana
Oct 12, 2018·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·Josef GuberChristophe Valmaggia
Jan 10, 2019·Ophthalmic Research·Rino FrisinaEdoardo Midena
Mar 19, 2019·Journal of Ophthalmology·Ferdinando Bottoni

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Citations

Mar 2, 2021·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·M MaierC Haritoglou
May 18, 2021·Klinische Monatsblätter für Augenheilkunde·Felix HagenauSiegfried Priglinger
Nov 9, 2021·The Cochrane Database of Systematic Reviews·Declan C MurphyDavid Hw Steel

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