The management of suspected pancreatic sepsis

Gastroenterology Clinics of North America
Tyler M BerzinPeter A Banks

Abstract

The management of infected pancreatic necrosis is centered on image-guided fine needle aspiration followed by antibiotic therapy that is based on microbiologic culture results. The authors favor targeted antibiotic therapy rather than routine prophylactic antibiotic coverage. Prompt surgical debridement is recommended for patients who have infected necrosis who are suitable operative candidates. Newer surgical, percutaneous, and endoscopic techniques, as well as prolonged antibiotic therapy without intervention, are being evaluated as alternatives to operative debridement. Well-designed prospective trials will help to determine optimal treatment for patients who have infected pancreatic necrosis.

References

Nov 7, 2007·The British Journal of Surgery·T L BollenDutch Acute Pancreatitis Study Group
Jul 1, 2008·Journal of Vascular and Interventional Radiology : JVIR·Tyler M BerzinKoenraad J Mortele

Citations

Apr 1, 1975·American Journal of Surgery·S J CamerJ W Braasch
Nov 18, 1995·Lancet·G TydénA S Malmborg
Apr 1, 1994·Antimicrobial Agents and Chemotherapy·C BassiE M Bertazzoni
Sep 1, 1994·Gastroenterology·P C SedmanD Johnstone
Apr 8, 1998·AJR. American Journal of Roentgenology·P C FreenyM N Sinanan
Jul 14, 1999·Gut·S W SchmidM W Büchler
Mar 23, 2002·World Journal of Surgery·Peter GötzingerReinhold Függer
May 16, 2003·Digestive Surgery·S ConnorJ P Neoptolemos
Sep 26, 2003·Pancreas·Zong-Guang ZhouZhao-Da Zhang
Feb 21, 2004·AJR. American Journal of Roentgenology·J Darío CasasPatricia Cuadras
Apr 2, 2004·Gastroenterology·R IsenmannGerman Antibiotics in Severe Acute Pancreatitis Study Group
Aug 13, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Liliana SimonJacques Lacroix
Mar 19, 2005·Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]·H G BegerB Poch
Mar 23, 2005·Pancreas·Michael RunziPeter Layer
Oct 20, 2005·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Gulam M KhanScott Tenner
Jan 21, 2006·Surgical Endoscopy·L WeckmanJ Halttunen

Related Concepts

Septicemia
Endoscopy (Procedure)
Necrosis
Pancreatitis
Fine Needle Aspiration Biopsy
Drugs used in migraine prophylaxis
Pancreatic Diseases
Sepsis (Invertebrate)
Infected Pancreatic Necrosis
Antibiotics

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Synapse Loss as Therapeutic Target in MS

As we age, the number of synapses present in the human brain starts to decline, but in neurodegenerative diseases this occurs at an accelerated rate. In MS, it has been shown that there is a reduction in synaptic density, which presents a potential target for treatment. Here is the latest research on synapse loss as a therapeutic target in MS.

Artificial Intelligence in Cardiac Imaging

Artificial intelligence (ai) techniques are increasingly applied to cardiovascular (cv) medicine in cardiac imaging analysis. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

Social Learning

Social learning involves learning new behaviors through observation, imitation and modeling. Follow this feed to stay up to date on the latest research.

Cell Atlas of the Human Eye

Constructing a cell atlas of the human eye will require transcriptomic and histologic analysis over the lifespan. This understanding will aid in the study of development and disease. Find the latest research pertaining to the Cell Atlas of the Human Eye here.

Single Cell Chromatin Profiling

Techniques like ATAC-seq and CUT&Tag have the potential to allow single cell profiling of chromatin accessibility, histones, and TFs. This will provide novel insight into cellular heterogeneity and cell states. Discover the latest research on single cell chromatin profiling here.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells.

Related Papers

Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
Tyler M BerzinPeter A Banks
Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
W UhlInternational Association of Pancreatology
© 2020 Meta ULC. All rights reserved