The many faces of IgG4-related disease: report of a case with inaugural recurrent aortic aneurism ruptures and literature review

Rheumatology International
Mariana LuísArmando Malcata

Abstract

Vascular involvement in IgG4-related disease (IgG4-RD), is a well-recognized feature and large vessel commitment, especially the aorta, can be the only manifestation of the disease. Being a newly recognized disease, its diagnosis and workup still represents a challenge in clinical practice. A 47-year-old-man with two aortic aneurysms ruptures, one at abdominal and the other at thoracic level, was referred to our rheumatology department. The initial analysis of the surgical specimen obtained 3 years earlier revealed a nonspecific aortitis. Re-evaluation of the biopsy with immunohistology now demonstrated the presence of IgG4 deposits. Evidence-based recommendations regarding diagnosis, treatment and follow-up of IgG4-related large-vessel involvement are lacking. In this particular case, histopathology were crucial. The authors review and discuss vascular involvement in IgG4-RD and respective treatment options.

References

Oct 1, 2009·Arthritis and Rheumatism·John H StoneJames R Stone
Aug 4, 2010·Journal of Vascular Surgery·Satomi KasashimaYasuni Nakanuma
Nov 3, 2010·Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology·Jan LacoJan Vojacek
Dec 3, 2010·Current Opinion in Rheumatology·Augusto VaglioCarlo Salvarani
Dec 3, 2010·Current Opinion in Rheumatology·Satomi Kasashima, Yoh Zen
Oct 1, 2011·The Annals of Thoracic Surgery·Kyeongmin ByeonDuk-Kyung Kim
Oct 17, 2012·Seminars in Diagnostic Pathology·Yoh ZenDai Inoue
Nov 2, 2012·Current Opinion in Rheumatology·Sebastian UnizonyJames R Stone
Mar 8, 2013·La Presse médicale·John H Stone
Jul 3, 2013·The Journal of Rheumatology·Sarah LiptonPascale Schwab
Apr 4, 2014·The Annals of Thoracic Surgery·Sébastien ColombierLars Niclauss
Jun 6, 2014·International Heart Journal·Miyu TajimaYukio Hiroi
Aug 8, 2014·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Satomi KasashimaYouhei Marukawa
Sep 10, 2014·The Journal of Thoracic and Cardiovascular Surgery·Joseph J Maleszewski
Feb 11, 2015·Annals of the Rheumatic Diseases·Mollie N CarruthersJohn H Stone
Mar 24, 2015·Reumatología clinica·David Alejandro Herrera van OostdamCarlos Abud-Mendoza
Mar 27, 2015·Arthritis & Rheumatology·A KhosroshahiUNKNOWN Second International Symposium on IgG4-Related Disease
Jul 29, 2015·Auto- Immunity Highlights·Abo-Helo Nizar, Elias Toubi
Mar 18, 2016·VASA. Zeitschrift für Gefässkrankheiten·Ludwig Caspary
Jun 16, 2016·Internal Medicine·Shunsuke NishimuraYoshihisa Nakagawa
Jul 20, 2016·Medicine·Cory A PeruginoJohn H Stone
Jul 20, 2016·Canadian Journal of Kidney Health and Disease·Shawna MannLuke Y C Chen
Jul 29, 2016·Seminars in Liver Disease·Terumi KamisawaKazuro Chiba
Jan 1, 2013·SAGE Open Medical Case Reports·Shuichi FujitaNobukazu Ishizaka
Dec 29, 2016·European Journal of Radiology·Sophie MavrogeniGenovefa Kolovou
Feb 22, 2017·The Annals of Thoracic Surgery·Min Jae ChaEun Sung Lee
Mar 12, 2017·Annals of the Rheumatic Diseases·Hisanori UmeharaTsutomu Chiba
May 12, 2017·Journal of Clinical Ultrasound : JCU·Anand K NarayanJoel Fradin

❮ Previous
Next ❯

Citations

Apr 6, 2019·PLoS Genetics·Andy DahlNoah Zaitlen

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiac Aneurysm

Aneurysm refers to a bulge of the wall or lining of a vessel commonly occurring in the blood vessels at the base of the septum or within the aorta. In the heart, it usually arises from a patch of weakened tissue in a ventricular wall, which swells into a bubble filled with blood. Discover the latest research on cardiac aneurysm here.

Aortic Aneurysm

An aortic aneurysm is the weakening and bulging of the blood vessel wall in the aorta. This causes dilatation of the aorta, which is usually asymptomatic but carries the risk of rupture and hemorrhage. Find the latest research on aortic aneurysms here.

Aneurysm

Aneurysms are outward distensions or bulges that occurs in a weakened wall of blood vessels. Discover the latest research on aneurysms here.

Related Papers

Revista portuguesa de cirurgia cardio-torácica e vascular : órgão oficial da Sociedade Portuguesa de Cirurgia Cardio-Torácica e Vascular
Bruno FernandesLina Carvalho
Tip Fakültesi mecmuasi
H Z KonuralpB Görgün
Circulation Journal : Official Journal of the Japanese Circulation Society
Antonio LaluezaCarlos Lumbreras
© 2022 Meta ULC. All rights reserved