The marine Omega3 wound matrix for treatment of complicated wounds: A multicenter experience report

Gefässchirurgie : Zeitschrift für vaskuläre und endovaskuläre Chirurgie : Organ der Deutschen und der Österreichischen Gesellschaft für Gefässchirurgie unter Mitarbeit der Schweizerischen Gesellschaft für Gefässchirurgie
B DorweilerH Diener

Abstract

The Kerecis™ Omega3 Wound matrix is a decellularized skin matrix derived from fish skin and represents an innovative concept to achieve wound healing. The aim of this study was to report the cumulative experience of three centers for vascular surgery regarding use of the Omega3 Wound matrix in selected patients with complicated wounds. In this study 23 patients with 25 vascular and/or diabetes mellitus-associated complicated wounds and partially exposed bony segments were treated with the Omega3 Wound matrix in three vascular centers. In several patients, conventional wound treatment with vacuum therapy had previously been carried out sometimes over several weeks without durable success. Following initial debridement in the operating room, the matrix was applied and covered with a silicone mesh. In the further course, wound treatment was conducted on an outpatient setting if possible. In total 25 wounds were treated with localization at the level of the thigh (n = 2), the distal calf (n = 7), the forefoot (n = 14) and the hand (n = 2). The time to heal varied between 9 and 41 weeks and between 3 and 26 wound matrices were applied per wound. Interestingly, a reduction of analgesics intake was noted when the treatment with the Om...Continue Reading

References

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May 1, 2008·The British Journal of Surgery·D T UbbinkH Vermeulen
Mar 27, 2009·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Gregory S Schultz, Annette Wysocki
Jan 22, 2010·The Clinical Journal of Pain·Gordon D KoAnnie Hum
Nov 6, 2012·Progress in Lipid Research·Alexandra C Kendall, Anna Nicolaou
Aug 21, 2013·Journal of Dermatological Science·Nicholas S GreavesArdeshir Bayat
Mar 15, 2015·Journal of Wound Care·A M Reyzelman, I Bazarov
May 27, 2015·The Journal of Pharmacy and Pharmacology·Graciela E EscuderoCarlos H Laino
Jun 16, 2015·Journal of Wound Care·M L Williams, J E Holewinski
Jan 26, 2016·Journal of Vascular Surgery·Tarig ElraiyahMohammad Hassan Murad
Jan 26, 2016·Journal of Vascular Surgery·Tarig ElraiyahMohammad Hassan Murad

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Citations

Dec 12, 2019·Journal of Tissue Engineering and Regenerative Medicine·Aristotelis KotronoulasÓttar Rolfsson
Dec 19, 2019·Frontiers in Bioengineering and Biotechnology·Tiago CostaTeresa Viseu
Jul 7, 2021·Materials Science & Engineering. C, Materials for Biological Applications·Dongsheng LiXiumei Mo
Nov 26, 2021·Experimental Dermatology·Anna-Lena SeveringEwa Klara Stürmer
Nov 30, 2021·American Journal of Veterinary Research·Elise S MauerDaniel Spector

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Methods Mentioned

BETA
amputation
percutaneous transluminal angioplasty
amputations

Software Mentioned

Image J
Fiji
MS EXCEL
AKESTES ©

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