PMID: 11904612Mar 21, 2002Paper

The Maternal Lifestyle Study: drug exposure during pregnancy and short-term maternal outcomes

American Journal of Obstetrics and Gynecology
Charles BauerJoel Verter

Abstract

Reports of maternal effects resulting from drug exposure during pregnancy are inconsistent. The Maternal Lifestyle Study (MLS) is a multicenter, prospective, observational study that was initiated to better define the effects of exposure to illicit drugs during pregnancy on the mother, fetus, and infant. Between May 1993 and May 1995, of 19,079 mother-infant dyads that were screened after delivery for cocaine and opiate exposure at four clinical centers (Brown University, University of Miami, University of Tennessee, Memphis, and Wayne State University), 16,988 (89%) met eligibility criteria and 11,811 (70%) of those eligible agreed to participate in the study. Exposure was defined as an admission of use of cocaine or opiates or both or the presence of cocaine or opiate metabolites in meconium as determined by use of gas chromatography-mass spectroscopy assay. Nonexposure was defined as a negative drug use history by interview and a negative immunoassay screen. When exposure could not be confirmed, such as when meconium was not obtained or was inadequate for confirmatory analysis, the mother-infant dyad was excluded (n = 3184). Of the mothers who consented to participate, 50% were African American, 38% were married, 64% were Me...Continue Reading

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References

Aug 1, 1990·American Journal of Obstetrics and Gynecology·W GonsoulinK J Moise
Nov 1, 1985·Journal of Clinical Psychology·K BurnsR Hatcher
Dec 1, 1993·American Journal of Public Health
Sep 1, 1994·Archives of Pediatrics & Adolescent Medicine·L SingerR Kliegman
Dec 1, 1993·American Journal of Diseases of Children·D R Wasserman, J M Leventhal
Feb 1, 1997·Pediatrics·M BehnkeN S Woods
Feb 1, 1997·The Journal of Pediatrics·C G SisonV Salari

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Citations

Mar 21, 2007·Analytical and Bioanalytical Chemistry·Teresa Gray, Marilyn Huestis
Jul 16, 2008·Child Psychiatry and Human Development·Daniel M BagnerAbhik Das
Sep 16, 2008·Journal of Urban Health : Bulletin of the New York Academy of Medicine·Ashley H Schempf, Donna M Strobino
Apr 22, 2010·American Journal of Perinatology·Ronnesia B GaskinsMary Roberts
Mar 9, 2012·American Journal of Perinatology·Rizwan ShahBarry M Lester
Apr 22, 2010·Journal of Addictive Diseases·Loretta P Finnegan
Apr 22, 2010·Journal of Addictive Diseases·Binta LambertDeborah Campbell
Feb 24, 2012·Journal of Addictive Diseases·Tina Birk IrnerMay Olofsson
Feb 24, 2012·Journal of Addictive Diseases·Tina Birk IrnerMay Olofsson
Jan 5, 2011·Journal of Developmental and Behavioral Pediatrics : JDBP·Toni M WhitakerRosemary Higgins
Apr 11, 2012·Journal of Developmental and Behavioral Pediatrics : JDBP·Todd P LevineMary B Roberts
Aug 24, 2002·Archives of Disease in Childhood. Fetal and Neonatal Edition·H S BadaP L Maza
Aug 26, 2003·Archives of Disease in Childhood. Fetal and Neonatal Edition·L L LaGasseJ Liu
Apr 18, 2009·Developmental Neuroscience·Michael J CrowleyLinda C Mayes
Jun 11, 2008·Pediatrics·Todd P LevineRosemary Higgins
Dec 9, 2009·Pediatrics·Jing LiuHenrietta Bada
Mar 8, 2014·Women's Health·Simone M Goettler, Sibil Tschudin
Feb 9, 2010·Journal of Women's Health·Mishka TerplanSarah H Glavin
Sep 9, 2005·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·O C EzechiG C E Okeke
Nov 12, 2005·Substance Use & Misuse·Joy C Draper, Elinore F McCance-Katz
Nov 23, 2006·Substance Use & Misuse·Robert M MalowJanet S St Lawrence
May 23, 2014·Obstetrics and Gynecology Clinics of North America·Mary Beth SutterAndrew Hsi
Sep 4, 2012·Clinics in Laboratory Medicine·Steven W Cotten
Aug 3, 2006·Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN·Carol Shieh, Melva Kravitz
May 30, 2008·Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN·Jeanne L Alhusen
Oct 11, 2011·Infant Behavior & Development·John D HaltiganDaniel S Messinger
May 14, 2011·Women's Health Issues : Official Publication of the Jacobs Institute of Women's Health·Sharada WeirRobin E Clark
Nov 27, 2010·Neurotoxicology and Teratology·Linda L LaGasseMary Roberts
Aug 17, 2010·Journal de gynécologie, obstétrique et biologie de la reproduction·L Simmat-DurandC Lejeune
Apr 20, 2010·The Journal of Pediatrics·Barry M LesterRosemary Higgins
Dec 1, 2009·Obstetrics and Gynecology Clinics of North America·Brittany B Albright, William F Rayburn
Dec 9, 2008·Neurotoxicology and Teratology·Monica S PazBarry M Lester
Aug 1, 2008·Journal de gynécologie, obstétrique et biologie de la reproduction·A DumasL Mandelbrot
Dec 8, 2007·Clinics in Perinatology·William F Rayburn
Feb 13, 2007·Seminars in Fetal & Neonatal Medicine·Ilana B Crome, Manoj T Kumar
Jan 30, 2007·Neurotoxicology and Teratology·Amy L SalisburyKen Poole
May 18, 2004·Child Development·Ronald SeiferJing Liu
Feb 13, 2007·Child: Care, Health and Development·J MilesS W D'Souza
Mar 10, 2007·Annals of the New York Academy of Sciences·Linda L LagasseAbhik DAS

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