The Mayo Clinic experience with surgical management, complications and outcome for patients with renal cell carcinoma and venous tumour thrombus

BJU International
Michael L BluteHorst Zincke

Abstract

To report the surgical management, complications and outcomes over three decades by tumour thrombus level for patients with renal cell carcinoma (RCC) and renal venous extension, as surgery is the most effective treatment. We assessed 540 patients who underwent surgical resection for RCC with renal venous extension between 1970 and 2000. Early and late surgical complications, including operative mortality, were compared with tumour thrombus level using the chi-square, Fisher's exact and Wilcoxon rank-sum tests. Cancer-specific survival was estimated using the Kaplan-Meier method and compared across tumour thrombus levels using log-rank tests. There were 349 (64.6%) patients with level 0 thrombus and 191 (35.4%) with inferior vena cava thrombus, including 66 (12.2%) with level I, 77 (14.3%) with level II, 28 (5.2%) with level III, and 20 (3.7%) with level IV thrombus. Patients with a higher thrombus level had more early surgical complications (respectively for level 0 to IV, 8.6%, 15.2%, 14.1%, 17.9% and 30.0%, P < 0.001). However, there was no statistically significant difference in the incidence of late complications by thrombus level (P = 0.445). The incidence of any early surgical complication decreased from 13.4% for patien...Continue Reading

References

Aug 1, 1978·The Journal of Urology·J B DekernionR B Smith
Mar 1, 1992·Journal of Computer Assisted Tomography·D A KallmanM L Blute
Jan 1, 1991·The Journal of Urology·P A HatcherJ E Robertson
Feb 1, 1990·The Journal of Urology·W S Chung, H K Choi
May 1, 1987·British Journal of Urology·R J Neves, H Zincke
Feb 1, 1980·The Journal of Urology·R V ClaymanE E Fraley
Aug 1, 1994·American Journal of Surgery·D J SwierzewskiJ A Libertino
Dec 11, 2002·American Journal of Clinical Pathology·Christine M LohseJohn C Cheville
Apr 30, 2003·The American Journal of Surgical Pathology·John C ChevilleMichael L Blute

❮ Previous
Next ❯

Citations

Aug 15, 2013·Der Urologe. Ausg. A·M WeberZ Halloul
Nov 29, 2008·World Journal of Urology·Benjamin J CoonsPeter E Clark
Oct 23, 2012·International Urology and Nephrology·Abhinav SidanaRonald Rodriguez
Nov 5, 2011·Current Urology Reports·Javier González
Mar 21, 2013·The Surgeon : Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland·R G CaseyT H Lynch
Jan 11, 2008·Nature Clinical Practice. Urology·Matthew F WszolekJohn A Libertino
May 15, 2008·Nature Clinical Practice. Urology·R Jeffrey Karnes, Michael L Blute
Jun 14, 2008·Interactive Cardiovascular and Thoracic Surgery·Maninder S KalkatTimothy R Graham
May 25, 2011·AJR. American Journal of Roentgenology·Brian F ChapinChristopher G Wood
Nov 6, 2012·Nihon Hinyōkika Gakkai zasshi. The japanese journal of urology·Hiroki ChibaKouichi Kanagawa
Apr 1, 2014·Current Urology Reports·Juan I Martínez-SalamancaJohn A Libertino
Apr 23, 2014·World Journal of Urology·Nnenaya Agochukwu, Brian Shuch
Jan 17, 2015·Texas Heart Institute Journal·Magdy M El-Sayed AhmedJoseph S Coselli
Oct 15, 2013·Cirugía española·Patricia González MartínezReyes Vega Manrique
Dec 3, 2014·Urology·Karin E WestessonVenkatesh Krishnamurthi
Jun 6, 2009·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Brett Delahunt
Nov 19, 2013·Expert Review of Anticancer Therapy·Javier GonzálezGaetano Ciancio
Feb 3, 2016·The Annals of Thoracic Surgery·Mario GaudinoLeonard N Girardi
Aug 2, 2011·Actas urologicas españolas·G García-FadriqueJ F Jiménez-Cruz
Sep 21, 2013·Journal of Cardiothoracic and Vascular Anesthesia·Kyota FukazawaGaetano Ciancio
Jan 24, 2016·Urology·Daniel RamirezGeorges-Pascal Haber
Sep 10, 2015·Journal of Surgical Oncology·Peter A CaputoRobert Stein
Aug 14, 2012·Journal of Cardiothoracic and Vascular Anesthesia·Gaurav MalhotraFeroze Mahmood
Apr 13, 2012·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·H MiyakeM Fujisawa
Sep 13, 2015·The Journal of Urology·Nick W LiuJonathan A Coleman
Jan 13, 2012·Urologic Oncology·Adam C ReeseMaxwell V Meng
Jul 26, 2011·The Journal of Thoracic and Cardiovascular Surgery·Jose L NaviaBruce W Lytle
Oct 29, 2010·European Urology·Juan I Martínez-SalamancaUNKNOWN International Renal Cell Carcinoma-Venous Thrombus Consortium
Jul 21, 2010·The Journal of Urology·Frédéric PouliotArie S Belldegrun
Dec 8, 2009·Urology·Dario Fontana, Paolo Destefanis

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.