The measurement of end-tidal carbon dioxide (PETCO2) is not a significant parameter to monitor in patients with severe traumatic brain injury

Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie
P SeguinYannick Malledant

Abstract

To evaluate the agreement between end-tidal carbon dioxide (PETCO2) and arterial CO2 (PaCO2) in patients with traumatic brain injury and to document the course of the (PaCO2-PETCO2) gradient over time. Twenty one traumatic brain injury patients (Coma Glasgow Scale < or = 8) were included in this prospective observational study over a period of six months. Simultaneous determinations of PaCO2 and PETCO2 (by infrared capnometry) were recorded. Agreement between PaCO2 and PETCO2 was determined by the statistical method described by Bland and Altman. Changes in PETCO2 over time were compared with changes in PaCO2. Factors likely to explain a gradient superior to +/- 4 mmHg were explored. One hundred and eleven data pairs were obtained. The bias was 5.5 mmHg with a precision of 5.1 mmHg and limits of agreement ranged from -4.5 mmHg to 15.5 mmHg. The latter exceeded the predefined limits of agreement established to determine interchangeability between methods (+/- 4 mmHg). PETCO2 and PoCO2 changed in opposite directions in 20% of 90 consecutive measurements. Only the duration of ventilation was found to be significantly associated with a gradient superior to +/- 4 mmHg. In this selected population of patients with severe traumatic br...Continue Reading

References

Jul 1, 1992·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·K Bhavani-ShankarY Delph
Apr 1, 1991·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·R W Wahba
Jul 1, 1990·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·G B RussellJ C Strout
Jul 1, 1990·Critical Care Medicine·R C Mackersie, T G Karagianes
Nov 1, 1989·The American Review of Respiratory Disease·R A HoffmanM A Sackner
Feb 1, 1993·The Journal of Trauma·R M ChesnutM A Foulkes
Oct 1, 1992·Journal of Neurosurgical Anesthesiology·M Engoren
Oct 1, 1992·Journal of Neurosurgical Anesthesiology·G B Russell, J M Graybeal

❮ Previous
Next ❯

Citations

Aug 12, 2015·Current Opinion in Anaesthesiology·Martin Siegemund, Luzius A Steiner
Jun 11, 2020·Acta Anaesthesiologica Scandinavica·Raisa R RentolaJohanna Hästbacka
Jun 21, 2007·European Journal of Anaesthesiology·B VivienB Riou
Oct 3, 2008·Neurosurgical Focus·Shirley I Stiver, Geoffrey T Manley

❮ Previous
Next ❯

Related Concepts

Related Feeds

Brain Injury & Trauma

brain injury after impact to the head is due to both immediate mechanical effects and delayed responses of neural tissues.