The Mechanical Interpretation of Ocular Response Analyzer Parameters

BioMed Research International
Xiao QinLin Li

Abstract

Ocular Response Analyzer (ORA) is one of the most widely used devices in clinic, while the mechanical interpretations of parameters obtained from ORA have not been understood completely. The aim of this research is to explore the mechanical interpretation of ORA parameters. Rabbits aged 3-24 months were measured with ORA in vivo and corneal strips uniaxial tensile tests to get ORA parameters and corneal biomechanical parameters (corneal elastic modulus, relaxation time, and relaxation limit). The mechanical interpretation of ORA parameters was cognized preliminarily by analyzing the correlation between ORA parameters and corneal biomechanical parameters. On the other hand, finite element method was applied to simulate ORA measurements with different corneal biomechanical parameters to obtain quantitative relationship between ORA parameters and corneal biomechanical parameters further. Biomechanical experimental results showed that Corneal Resistance Factor (CRF) was correlated with corneal elastic modulus and relaxation limit significantly, while the significant correlations between Corneal Hysteresis (CH) and corneal biomechanical parameters were not observed. Results of finite element analysis showed that both CH and CRF were...Continue Reading

References

Jul 20, 2006·Journal of the Royal Society, Interface·K AndersonT Newson
Jul 20, 2006·Journal of the Royal Society, Interface·Ahmed Elsheikh, Kevin Anderson
Mar 17, 2007·Current Eye Research·Ahmed ElsheikhDavid Pye
Apr 9, 2008·Experimental Eye Research·Ahmed ElsheikhPaolo Rama
Oct 7, 2008·Investigative Ophthalmology & Visual Science·Xabier Larrea, Philippe Büchler
Dec 17, 2009·Journal of Biomechanics·H StuderP Büchler
Mar 26, 2010·Investigative Ophthalmology & Visual Science·Sabine KlingSusana Marcos
Feb 22, 2011·Journal of Cataract and Refractive Surgery·Derek W DelMonte, Terry Kim
Apr 30, 2014·Journal of Cataract and Refractive Surgery·Cynthia J Roberts, William J Dupps
May 13, 2014·Journal of the Mechanical Behavior of Biomedical Materials·Hamed Hatami-Marbini, Abdolrasol Rahimi
Feb 25, 2015·Journal of Cataract and Refractive Surgery·Hamed Hatami-Marbini, Abdolrasol Rahimi
Apr 19, 2015·Experimental Eye Research·Hamed Hatami-Marbini, Abdolrasol Rahimi
Jul 1, 2015·Current Eye Research·Hamed Hatami-Marbini, Abdolrasol Rahimi
Aug 13, 2015·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·G JóhannessonC Lindén
May 4, 2016·Proceedings of the National Academy of Sciences of the United States of America·Sungmin NamOvijit Chaudhuri
Jun 6, 2016·Ultrasonics·Li-Ke WangYong-Ping Zheng
Jun 13, 2017·Experimental Eye Research·FangJun BaoAhmed Elsheikh
Sep 12, 2017·Ophthalmic Epidemiology·Ali Riza Cenk CelebiC Banu Cosar Yurteri

❮ Previous
Next ❯

Software Mentioned

SPSS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology
Rui LiuLin Wang
Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)
Ying HonAndrew K C Lam
Journal of Research in Medical Sciences : the Official Journal of Isfahan University of Medical Sciences
Mohammad Reza SedaghatMojtaba Abrishami
© 2021 Meta ULC. All rights reserved