The mechanism of TGF-β signaling during palate development

Oral Diseases
Junichi IwataYang Chai

Abstract

Cleft palate, a malformation of the secondary palate development, is one of the most common human congenital birth defects. Palate formation is a complex process resulting in the separation of the oral and nasal cavities that involves multiple events, including palatal growth, elevation, and fusion. Recent findings show that transforming growth factor beta (TGF-β) signaling plays crucial roles in regulating palate development in both the palatal epithelium and mesenchyme. Here, we highlight recent advances in our understanding of TGF-β signaling during palate development.

References

Dec 24, 1992·The New England Journal of Medicine·A E Czeizel, I Dudás
Feb 1, 1989·Developmental Biology·J E Fitchett, E D Hay
Jan 1, 1984·Current Topics in Developmental Biology·W J Ferguson
Dec 1, 1995·Nature Genetics·G ProetzelT Doetschman
Aug 1, 1995·Circulation Research·M L Kirby, K L Waldo
Jan 1, 1995·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·Charles F Shuler
Nov 1, 1996·The Journal of Clinical Investigation·J J LetterioA B Roberts
Dec 12, 1997·Biochimica Et Biophysica Acta·Rik Derynck, X H Feng
Feb 14, 1998·Cytokine & Growth Factor Reviews·G R Grotendorst
May 9, 1998·Proceedings of the National Academy of Sciences of the United States of America·X YangChuxia Deng
Aug 5, 1998·Proceedings of the National Academy of Sciences of the United States of America·M WeinsteinC X Deng
Dec 29, 1998·Cell·Rik DerynckX H Feng
Feb 2, 1999·Oncogene·Lopa MishraBibhuti Mishra
Jul 27, 1999·British Journal of Orthodontics·T HartridgeJ R Sandy
Feb 7, 2001·Developmental Biology·Concepción Martínez-AlvarezM W Ferguson
Apr 25, 2000·The EMBO Journal·J Massagué, D Wotton
May 22, 2001·Molecular Biology of the Cell·L BlavierV Kaartinen
Nov 21, 2001·Nature Reviews. Genetics·E A Lindsay
Jul 23, 2002·Nature Cell Biology·José G AbreuE M De Robertis
Feb 25, 2003·Nature Genetics·Enid R NeptuneHarry C Dietz
May 24, 2003·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·Yang ChaiJ Han
Nov 1, 1958·Plastic and Reconstructive Surgery and the Transplantation Bulletin·L A PEERG C PECK
Jan 20, 2004·Developmental Biology·Marek DudasVesa Kaartinen
Feb 10, 2004·Frontiers in Bioscience : a Journal and Virtual Library·Tongwen Wang, Patricia K Donahoe
Mar 5, 2004·European Journal of Orthodontics·Martyn T Cobourne
Jun 17, 2004·The Journal of Clinical Investigation·Jeffrey C Murray, Brian C Schutte
Jun 17, 2004·The Journal of Clinical Investigation·Ritva RiceDavid P C Rice
Jul 6, 2004·Nature Genetics·Takeshi MizuguchiNaomichi Matsumoto
Jan 15, 2005·Developmental Biology·Xiao-Mei CuiCharles F Shuler
Oct 11, 2005·Annual Review of Cell and Developmental Biology·Xin-Hua Feng, Rik Derynck
Nov 8, 2005·American Journal of Medical Genetics. Part C, Seminars in Medical Genetics·Harry C DietzFrancesco Ramirez
Nov 30, 2005·Journal of Anatomy·Sylvia A HilliardYi Ping Chen
Dec 6, 2005·Lancet·Daniel P Judge, Harry C Dietz
Feb 18, 2006·The Journal of Biological Chemistry·Xu Shi-wenA Leask
May 9, 2006·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Yang Chai, Robert E Maxson
May 30, 2006·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Steven GoudyRichard J H Smith
Jun 27, 2006·Human Mutation·Krishna Kumar SinghMine Arslan-Kirchner
Aug 25, 2006·The New England Journal of Medicine·Bart LoeysHarry C Dietz
Sep 7, 2006·The Journal of Clinical Investigation·Forbes D Porter
Sep 7, 2006·The Journal of Clinical Investigation·Luke J EngelkingGuosheng Liang
Jan 5, 2007·Journal of the American Society of Nephrology : JASN·Yingjian LiYouhua Liu
Mar 3, 2007·The Cleft Palate-craniofacial Journal : Official Publication of the American Cleft Palate-Craniofacial Association·Cláudia Berbert-Campos
Mar 10, 2007·Otolaryngologic Clinics of North America·Oneida A Arosarena
Jul 11, 2007·TheScientificWorldJournal·Paige SniderSimon J Conway
Aug 21, 2007·American Journal of Medical Genetics. Part a·Alexandre R VieiraEduardo E Castilla
Oct 30, 2007·Developmental Biology·Seung O KoYang Chai
Oct 31, 2007·Developmental Biology·Liang-Tung Yang, Vesa Kaartinen
Jan 26, 2008·Journal of Dental Research·A R Vieira
Feb 8, 2008·Genesis : the Journal of Genetics and Development·Liang-Tung YangVesa Kaartinen
Mar 18, 2008·Mechanisms of Development·Zhenyu MuJohn S Munger
Apr 22, 2008·Current Problems in Pediatric and Adolescent Health Care·Eileen F KastenTodd Leander Hicks
Apr 23, 2008·Pediatric Research·Nicholas J PanettaMichael T Longaker
Apr 24, 2008·Differentiation; Research in Biological Diversity·Elena Martínez-SanzConcepción Martínez-Alvarez
May 6, 2008·Plastic and Reconstructive Surgery·Thomas J SitzmanJeffrey R Marcus
Jun 27, 2008·The New England Journal of Medicine·Benjamin S BrookeHarry C Dietz
Jul 1, 2008·Mechanisms of Development·Wai-Yee LiVesa Kaartinen
Jul 9, 2008·Developmental Cell·Raghu Kalluri, Yuchi Han
Jul 12, 2008·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Judy L ChenGinny Curtin
Jul 16, 2008·Current Opinion in Otolaryngology & Head and Neck Surgery·Shervin Aminpour, Travis T Tollefson
Jul 23, 2008·Developmental Disabilities Research Reviews·Linda Cooper-BrownDon C Van Dyke
Sep 2, 2008·Nature Cell Biology·Alessandro SorrentinoMaréne Landström
Sep 9, 2008·The International Journal of Biochemistry & Cell Biology·Chih-Chiun Chen, Lester F Lau
Oct 14, 2008·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Bernard J CostelloMichele Clemens
Oct 17, 2008·Molecular Cell·Motozo YamashitaYing E Zhang
Dec 31, 2008·Cell Research·Ying E Zhang
Jan 10, 2009·Journal of Dental Research·L MengJ W Von den Hoff
Mar 4, 2009·European Journal of Medical Genetics·Marie-France Portnoï
Jun 6, 2009·Seminars in Orthodontics·Andrew C LidralSteven A Bullard
Jul 9, 2009·Oral Diseases·A JugessurN Kilpatrick
Aug 4, 2009·Trends in Cell Biology·Jong Seok KangRik Derynck
Sep 10, 2009·Journal of Medical Genetics·Adrianna MostowskaPawel P Jagodzinski
Sep 15, 2009·Lancet·Peter A MosseyWilliam C Shaw
Oct 10, 2009·The Journal of Craniofacial Surgery·Francesco MannaPier Camillo Parodi
Nov 4, 2009·Indian Journal of Plastic Surgery : Official Publication of the Association of Plastic Surgeons of India·Wenli YuKathy K H Svoboda
Mar 25, 2010·Oral Diseases·G L Wehby, Jeffrey C Murray

Citations

Sep 24, 2013·Genetic Testing and Molecular Biomarkers·Mingrui TangDi Wang
Aug 27, 2013·Human Molecular Genetics·Junichi IwataYang Chai
Apr 19, 2012·Development·Heather J Ray, Lee Niswander
Mar 23, 2013·Disease Models & Mechanisms·Neus Martínez-AbadíasJoan T Richtsmeier
Dec 30, 2011·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·Kyoko OkaYoshihiko Sawa
Apr 10, 2013·Epigenomics·Ratnam S SeelanRobert M Greene
Aug 12, 2014·Archives of Oral Biology·Akira NakajimaCharles F Shuler
Mar 15, 2016·Frontiers in Physiology·Madeleine L BurgJane C Figueiredo
May 16, 2015·Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft·Hidetaka MurataIwao Sato
Sep 2, 2014·International Journal of Pediatric Otorhinolaryngology·C François-FiquetM Doco-Fenzy
Jun 1, 2016·Gene Expression Patterns : GEP·Momoko WatanabeAtsushi Ohazama
Jul 30, 2016·Frontiers in Physiology·Hai-Lei DingDavid E Clouthier
Dec 17, 2014·Birth Defects Research. Part C, Embryo Today : Reviews·Mahdi A ShkoukaniPeter F Svider
Nov 11, 2014·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Cynthia R HillSteven Goudy
Feb 15, 2019·Proceedings of the National Academy of Sciences of the United States of America·Jinghua GuiOsamu Shimmi
Jun 1, 2019·Journal of Dental Research·Jingyuan LiYang Chai
Jul 16, 2019·Human Molecular Genetics·Katherine A WoodRaymond T O'Keefe
Sep 13, 2017·PloS One·David G BelairBarbara D Abbott
Oct 15, 2019·PLoS Genetics·Lulin HuangZhenglin Yang
Feb 19, 2020·The Cleft Palate-craniofacial Journal : Official Publication of the American Cleft Palate-Craniofacial Association·Evija Balode, Mara Pilmane
Jul 16, 2020·Birth Defects Research·Kurt ReynoldsChengji J Zhou
Jul 30, 2020·Birth Defects Research·Yu JiChengji J Zhou
Sep 14, 2017·International Journal of Molecular Medicine·Veronika ŽivicováBarbora Dvořánková
Nov 13, 2015·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Akiko SuzukiJunichi Iwata
Sep 30, 2018·Biophysics Reviews·Stefanie S PortelliRichmond W Jeremy
Jan 11, 2020·Frontiers in Cell and Developmental Biology·Katiúcia Batista Silva PaivaAriadne Letra
Nov 23, 2018·International Journal of Molecular Sciences·Akira NakajimaJun-Ichi Hanai
Jul 22, 2018·Journal of Developmental Biology·Joseph T TarrS N Popoff
Jan 29, 2019·Journal of Biomaterials Science. Polymer Edition·Aybuke Alici-GaripcanIbrahim Vargel
Jan 29, 2021·Frontiers in Cell and Developmental Biology·Brian Ho Ching ChanJoe Rainger

Related Concepts

Cleft Lip
Cleft Palate, Isolated
Mesothelium
Lateral Plate Mesoderm
Structure of Papilla Incisiva of Mouth
Signal Transduction
Gene Expression
Transforming Growth Factor beta
Smad Proteins
Birth

Related Feeds

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.