The mechanistic causes of peripheral intravenous catheter failure based on a parametric computational study

Scientific Reports
Russell PiperBarry J Doyle

Abstract

Peripheral intravenous catheters (PIVCs) are the most commonly used invasive medical device, yet up to 50% fail. Many pathways to failure are mechanistic and related to fluid mechanics, thus can be investigated using computational fluid dynamics (CFD). Here we used CFD to investigate typical PIVC parameters (infusion rate, catheter size, insertion angle and tip position) and report the hemodynamic environment (wall shear stress (WSS), blood damage, particle residence time and venous stasis volumes) within the vein and catheter, and show the effect of each PIVC parameter on each hemodynamic measure. Catheter infusion rate has the greatest impact on our measures, with catheter orientation also playing a significant role. In some PIVC configurations WSS was 3254 times higher than the patent vein, and blood damage was 512 times greater, when compared to control conditions. Residence time is geometry-dependent and decreases exponentially with increasing insertion angle. Stasis volume decreased with increasing infusion rate and, to a lesser degree, insertion angle. Even without infusion, the presence of the catheter changes the flow field, causing low velocity recirculation at the catheter tip. This research demonstrates how several ...Continue Reading

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Citations

Sep 11, 2018·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Peter J CarrClaire M Rickard
Dec 7, 2018·Journal of Thrombosis and Haemostasis : JTH·D WeissO M Rotman
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Jul 4, 2020·Journal of Infusion Nursing : the Official Publication of the Infusion Nurses Society·Elizabeth Morrell
Jan 9, 2021·Journal of Cardiovascular Translational Research·Halit YaakobovichDar Weiss
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Jun 17, 2021·Cardiovascular Engineering and Technology·Syed FaisalAlberto Aliseda
Jun 30, 2021·Journal of Perianesthesia Nursing : Official Journal of the American Society of PeriAnesthesia Nurses·Limin JiaYingzhi Wang

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Methods Mentioned

BETA
medical procedure

Software Mentioned

CCM +
STAR
CCM

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