The mediating effect of childhood abuse in sexual orientation disparities in tobacco and alcohol use during adolescence: results from the Nurses' Health Study II.

Cancer Causes & Control : CCC
Hee-Jin JunRosalind J Wright

Abstract

To examine the mediating effect of childhood abuse on sexual orientation disparities in tobacco and alcohol use during adolescence. We carried out analyses with data from over 62,000 women in the ongoing Nurses' Health Study II cohort who provided information on sexual orientation, childhood abuse occurring by age 11, and tobacco and alcohol use in adolescence. We used multivariate regression analyses, controlling for confounders, to estimate the mediating effect of childhood abuse on the association between sexual orientation and tobacco and alcohol use in adolescence. Lesbian and bisexual orientation and childhood abuse were positively associated with greater risk of tobacco and alcohol use during adolescence. For lesbians, the estimated proportion of excess tobacco and alcohol use in adolescence relative to use among heterosexual women that was mediated by abuse in childhood ranged from 7 to 18%; for bisexual women, the estimated proportion of excess use mediated by abuse ranged from 6 to 13%. Elevated childhood abuse in lesbian and bisexual women partially mediated excess tobacco and alcohol use in adolescence relative to heterosexual women. Interventions to prevent child abuse may reduce sexual orientation disparities in s...Continue Reading

References

Apr 1, 1994·American Journal of Public Health·M J EldersG A Giovino
Jan 1, 1997·Child Abuse & Neglect·D FinkelhorM A Straus
Jun 1, 1997·Child Abuse & Neglect·P A HarrisonT J Beebe
Jul 15, 1997·Statistics in Medicine·D Y LinV De Gruttola
Oct 26, 1999·Cancer Causes & Control : CCC·F E SpeizerC Hennekens
Jul 15, 2000·Journal of Abnormal Psychology·J D SwendsenA Hromi
Jan 6, 2001·Journal of Consulting and Clinical Psychology·S D CochranV M Mays
Sep 19, 2001·Health & Social Care in the Community·W. R. Downs, L. Harrison
Jan 5, 2002·Journal of Consulting and Clinical Psychology·M OrlandoK Jinnett
Jan 17, 2002·Clinical Psychology Review·Tracy L Simpson, William R Miller
Jan 31, 2002·American Journal of Public Health·Stephen T RussellNhan Truong
May 9, 2002·The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine·Daniel E Bontempo, Anthony R D'Augelli
Jun 27, 2002·American Journal of Public Health·Alicia K MatthewsRoberta Cassidy
May 3, 2003·Breast Cancer Research and Treatment·Mona OkashaGeorge Davey Smith
Apr 7, 2004·Archives of Pediatrics & Adolescent Medicine·S Bryn AustinA Lindsay Frazier
Oct 1, 2004·Cancer Causes & Control : CCC·Hao TangDileep G Bal
Jan 25, 2005·Journal of Women's Health·Patricia CaseDonna Spiegelman
Jun 29, 2005·Journal of Consulting and Clinical Psychology·Kimberly F BalsamTheodore P Beauchaine
Jul 1, 2005·American Journal of Epidemiology·Donna Spiegelman, Ellen Hertzmark
Aug 2, 2005·Alcohol·Ramona G Dumitrescu, Peter G Shields
Sep 15, 2006·Drug and Alcohol Dependence·Najat J ZiyadehS Bryn Austin
Sep 29, 2006·Gynecologic Oncology·Susan J JordanPenelope M Webb
Mar 28, 2007·British Journal of Cancer·N D FreedmanC C Abnet
Mar 29, 2007·Health Affairs·Sarah L BarberPandu Harimurti
Jun 6, 2007·Journal of Lesbian Studies·Laurie Drabble, Karen Trocki
Jul 14, 2007·Child Abuse & Neglect·Tonda L HughesLaura A Szalacha
Sep 4, 2007·International Journal of Cancer. Journal International Du Cancer·Veronica Wendy SetiawanBrian E Henderson
Dec 15, 2007·Journal of Studies on Alcohol and Drugs·Sharon C WilsnackKelly E Kinnison
Dec 20, 2007·International Journal of Cancer. Journal International Du Cancer·Neal D FreedmanChristian C Abnet
Feb 1, 2008·American Journal of Public Health·Alyssa EastonRandall Sell
Jun 14, 2008·Cancer Causes & Control : CCC·Jessica P Brown, J Kathleen Tracy
Jun 20, 2008·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·Claudio PelucchiCarlo La Vecchia
Jun 21, 2008·The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine·Hee-Jin JunRosalind J Wright
Nov 5, 2008·Archives of Pediatrics & Adolescent Medicine·Heather L CorlissS Bryn Austin
Dec 25, 2008·Methods in Molecular Biology·Yvonne M Coyle
Dec 25, 2008·Methods in Molecular Biology·Jennifer Permuth-Wey, Thomas A Sellers
Jan 7, 2009·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Jenny Permuth-WeyTuya Pal
Mar 1, 2008·American Journal of Men's Health·Laura Duberstein LindbergAlison Gemmill

❮ Previous
Next ❯

Citations

May 16, 2014·American Journal of Public Health·Heather L CorlissAlicia K Matthews
Apr 15, 2014·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Alicia K MatthewsTimothy Johnson
Oct 16, 2014·International Journal of Environmental Research and Public Health·Nicole P YuanTessa A Evans-Campbell
Mar 8, 2016·Drug and Alcohol Dependence·Robert W S CoulterRon D Stall
Jan 21, 2016·LGBT Health·Stewart C AlexanderCleveland G Shields
Mar 11, 2015·The Nurse Practitioner·Susan J Roberts
Jun 6, 2015·Women's Health Issues : Official Publication of the Jacobs Institute of Women's Health·Rhonda BrownTonda Hughes
Mar 11, 2015·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Wesley T O'NealElsayed Z Soliman
Apr 22, 2016·International Journal of Behavioral Medicine·Amy L AiChandler Yap
Feb 19, 2013·Women's Health Issues : Official Publication of the Jacobs Institute of Women's Health·Alicia K MatthewsLisa Alvy
Jul 30, 2014·Violence and Victims·Maria D H Koeppel, Leana Bouffard
Sep 21, 2019·The Western Journal of Emergency Medicine·Michelle Ren, Shahrdad Lotfipour
Aug 12, 2017·Cancer Causes & Control : CCC·Leslie V FarlandMarina Kvaskoff
Nov 15, 2017·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Holly R HarrisShelley S Tworoger
Jul 23, 2021·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Andrea Romanos-NanclaresA Heather Eliassen

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.