PMID: 9425657Jan 13, 1998Paper

The medical utility of genomics data in neuropsychiatry: mutational genetics versus association genetics

Current Opinion in Biotechnology
S J Peroutka

Abstract

The long anticipated 'genetic revolution' in neuropsychiatry has yet to have an impact on the practice of clinical medicine. Excitement in the 1980s over major genetic breakthroughs in schizophrenia and manic depression, for example, has been replaced in the late 1990s by the sobering realization that most common neuropsychiatric disorders are multifactorial. Despite considerable effort and resources, no 'causative' genetic variation has been identified that plays a definitive major role in any common neuropsychiatric disorder.

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Nov 13, 2001·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·M Catalano
May 23, 2001·Pharmacogenomics·K K Jain
Aug 12, 1999·American Journal of Human Genetics·M Catalano

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