The MemClin project: a prospective multi memory clinics study targeting early stages of cognitive impairment

BMC Geriatrics
Urban EkmanEric Westman

Abstract

There remains a lack of large-scale clinical studies of cognitive impairment that aim to increase diagnostic and prognostic accuracy as well as validate previous research findings. The MemClin project will amass large quantities of cross-disciplinary data allowing for the construction of robust models to improve diagnostic accuracy, expand our knowledge on differential diagnostics, strengthen longitudinal prognosis, and harmonise examination protocols across centres. The current article describes the Memory Clinic (MemClin) project's study-design, materials and methods, and patient characteristics. In addition, we present preliminary descriptive data from the ongoing data collection. Nine out of ten memory clinics in the greater Stockholm area, which largely use the same examination methods, are included. The data collection of patients with different stages of cognitive impairment and dementia is coordinated centrally allowing for efficient and secure large-scale database construction. The MemClin project rest directly on the memory clinics examinations with cognitive measures, health parameters, and biomarkers. Currently, the MemClin project has informed consent from 1543 patients. Herein, we present preliminary data from 835...Continue Reading

References

Jan 1, 1997·International Psychogeriatrics·R C PetersenE G Tangelos
Jun 2, 2001·Stroke; a Journal of Cerebral Circulation·L O WahlundUNKNOWN European Task Force on Age-Related White Matter Changes
Aug 25, 2004·Journal of Internal Medicine·R C Petersen
Jan 31, 2006·Neuroimaging Clinics of North America·Susanne G MuellerLaurel Beckett
Dec 8, 2009·Journal of Neurology, Neurosurgery, and Psychiatry·Arto NordlundAnders Wallin
Dec 16, 2010·International Journal of Geriatric Psychiatry·Andrew SimmonsChristian Spenger
Nov 10, 2012·Therapeutic Advances in Neurological Disorders·Mirko BiblJens Wiltfang
Jan 17, 2014·Frontiers in Neuroinformatics·J-Sebastian MuehlboeckAndrew Simmons
May 7, 2014·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·Frank JessenUNKNOWN Subjective Cognitive Decline Initiative (SCD-I) Working Group
Nov 9, 2016·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·José L MolinuevoUNKNOWN Subjective Cognitive Decline Initiative (SCD-I) Working Group
Apr 1, 2018·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·Lisa VermuntPieter Jelle Visser
Apr 15, 2018·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·Clifford R JackUNKNOWN Contributors
Aug 28, 2018·Neurobiology of Aging·Alejandra MachadoDaniel Ferreira
Oct 16, 2018·Journal of Alzheimer's Disease : JAD·Simona SacuiuIngmar Skoog
Nov 24, 2018·Social Psychiatry and Psychiatric Epidemiology·A Matthew PrinaMartin Prince
Dec 18, 2018·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·Rosalinde E R SlotWiesje M van der Flier

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Citations

May 27, 2021·Aging·John WallertUNKNOWN ADNI consortium, and MemClin steering committee

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Software Mentioned

MemClin
TheHiveDB

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