The MentalPlus® Digital Game Might Be an Accessible Open Source Tool to Evaluate Cognitive Dysfunction in Heart Failure with Preserved Ejection Fraction in Hypertensive Patients: A Pilot Exploratory Study

International Journal of Hypertension
Valeria Fontenelle Angelim Pereira, Livia Stocco Sanches Valentin

Abstract

Cognitive dysfunction with heart failure with reduced ejection fraction (HFrEF) is well studied. However, there are few comparative studies with heart failure and preserved ejection fraction (HFpEF). Cognitive dysfunction diagnosis usually demands a long neuropsychological battery. We developed MentalPlus® digital game to overwhelm that issue. As a pilot study, we evaluated 60 patients with systemic hypertension and HFpEF. They were submitted to TICS (Telephone Interview Cognitive Status) to evaluate the general cognitive function and 25 minutes of MentalPlus® digital game evaluation. The results disclosed 60 hypertensive patients. All of them presented with HFpEF. Patients presented a mean age of 56±10 years; 46% male; LVMi (g/m2) mean of 110±20; educational attainment of 9 years or more; mean income of 8 Brazilian minimum wages. The TICS results disclosed 28 ±3.7. MentalPlus® digital game evaluation disclosed preserved values for the phases I, III, IV, V, VI, and VII. Phase II, short-term memory related, was below the normals values that were assigned. This group of patients presented a normal general cognition by both evaluations, except for specific functions displayed above, disclosed by MentalPlus®. The MentalPlus® was de...Continue Reading

References

Feb 15, 1986·The American Journal of Cardiology·R B DevereuxN Reichek
Aug 2, 2005·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·Carlos A FeldsteinDelia Garrido
Jan 13, 2006·Archives of Internal Medicine·Lawrence LiaoJohn S Gottdiener
Jul 21, 2006·The New England Journal of Medicine·Theophilus E OwanMargaret M Redfield
Jul 21, 2006·The New England Journal of Medicine·R Sacha BhatiaPeter P Liu
Aug 4, 2009·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·Tamara G FongSharon K Inouye
Dec 18, 2009·Neuroepidemiology·Oscar L Lopez, Lewis H Kuller
Apr 26, 2011·European Journal of Cardiovascular Nursing : Journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology·Lisa BauerMary Filipi
Dec 27, 2011·Journal of Cardiac Failure·Irène OudejansArno W Hoes
Mar 24, 2012·Current Biology : CB·C S Green, D Bavelier
May 3, 2012·Journal of Mental Health·Fernando Fernández-ArandaEva Penelo
May 23, 2012·Circulation·Benjamin A SteinbergUNKNOWN Get With the Guidelines Scientific Advisory Committee and Investigators
Dec 15, 2012·Circulation·Alan S GoUNKNOWN American Heart Association Statistics Committee and Stroke Statistics Subcommittee
Mar 30, 2013·European Journal of Heart Failure·Aldo P MaggioniUNKNOWN Heart Failure Association of the European Society of Cardiology (HFA)
Jun 5, 2013·European Journal of Cardiovascular Nursing : Journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology·Karen HarknessRobert S McKelvie
Jun 7, 2013·Circulation·UNKNOWN WRITING COMMITTEE MEMBERSUNKNOWN American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines
Jun 22, 2014·Circulation Research·Kavita Sharma, David A Kass

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Citations

May 20, 2019·Current Treatment Options in Cardiovascular Medicine·Shannon WongvibulsinEvan D Muse

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Software Mentioned

MentalPlus
SPSS
MentalPlus®
Excel

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