The Merkel cell polyomavirus and its involvement in Merkel cell carcinoma

Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]
Kyle T AmberKeyvan Nouri

Abstract

The discovery of the Merkel cell polyomavirus (MCV) in a large number of Merkel cell carcinomas (MCCs) has led to many investigations into its potential role as an oncovirus. Many studies have recently explored the differences between MCCs infected and not infected with MCV. To review the role of MCV in MCC and its potential to influence diagnosis, prognosis, and treatment. An extensive literature search was performed on MCV and its relationship with other polyomaviruses and MCC. The immune system's role in MCC was also investigated. We included 60 articles regarding MCC and MCV and seven pertinent to general processes involved with MCC and MCV. Merkel cell polyomavirus appears to affect many aspects of MCC. An understanding of this virus may aid in future therapy options and current pathology protocols in diagnosing MCC. The host's immune function appears to affect MCV's ability to cause cellular transformation leading to MCC.

References

Feb 8, 2013·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Kenneth Beer
Dec 11, 2013·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Julie R Howle, Michael J Veness
Jul 1, 2014·Cancers·Janice E Ma, Jerry D Brewer
Jan 15, 2015·Digestive Diseases and Sciences·Yezaz A GhouriWilliam A Ross
May 9, 2014·The International Journal of Biochemistry & Cell Biology·Piotr Czapiewski, Wojciech Biernat
Aug 16, 2016·Current Opinion in Virology·Wei LiuJianxin You
Sep 22, 2016·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·R HoersterL M Heindl
Sep 10, 2015·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Sandro V PorcedduAlexander Guminski
Jan 15, 2014·Global Advances in Health and Medicine : Improving Healthcare Outcomes Worldwide·Kyle T Amber
Jan 15, 2014·Global Advances in Health and Medicine : Improving Healthcare Outcomes Worldwide·Barbara SickmüllerMarietta Kaszkin-Bettag
Jan 9, 2019·International Journal of Dermatology·Cyro Festa NetoPaulo R Urbano
Apr 3, 2019·Journal of Cutaneous Medicine and Surgery·Megan A SanderMatthew A Croxen
Mar 25, 2020·International Ophthalmology Clinics·Giancarlo A Garcia, Andrea L Kossler
Jan 25, 2017·Future Science OA·Ettore Minutilli, Antonino Mulè

Citations

Jan 1, 1972·Archives of Dermatology·C Toker
Jan 1, 1994·Nephron·M FormicaG Piccoli
Dec 1, 1995·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·A C DoudsS H Morgan
Apr 15, 1997·Proceedings of the National Academy of Sciences of the United States of America·W L Kelley, C Georgopoulos
May 1, 1997·Genes & Development·K S CampbellJames A DeCaprio
Oct 24, 1998·The New England Journal of Medicine·E J Lunder, R S Stern
Jan 27, 1999·Mutation Research·G M HallidayR S Barnetson
Feb 21, 2002·Lancet·Eric A EngelsRobert W Miller
Oct 25, 2003·Journal of the American Academy of Dermatology·Maria Agelli, Limin X Clegg
Dec 22, 2004·Journal of Surgical Oncology·Nicole C Hodgson
Feb 3, 2006·The Keio Journal of Medicine·Thomas Schwarz
Jun 21, 2006·Archives of Dermatology·Kevan G LewisClark C Otley
Sep 12, 2006·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Danielle L Poulin, James A DeCaprio
Mar 21, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Pablo MojicaJoshua D I Ellenhorn
Jan 19, 2008·Science·Huichen FengPatrick S Moore
Feb 19, 2008·Journal of the American Academy of Dermatology·Michelle HeathPaul Nghiem
Sep 25, 2008·Proceedings of the National Academy of Sciences of the United States of America·Masahiro ShudaYuan Chang
Nov 21, 2008·The Journal of Investigative Dermatology·Kelly G PaulsonPaul Nghiem
Apr 28, 2009·Advances in Anatomic Pathology·Melissa PulitzerKlaus J Busam
Apr 30, 2009·Journal of the National Comprehensive Cancer Network : JNCCN·Stanley J MillerNCCN Merkel Cell Carcinoma Panel
Jun 6, 2009·International Journal of Cancer. Journal International Du Cancer·Masahiro ShudaYuan Chang
Jun 6, 2009·International Journal of Cancer. Journal International Du Cancer·Yanis L TolstovPatrick S Moore
Jun 19, 2009·Journal of the National Cancer Institute·James A DeCaprio
Jun 19, 2009·Journal of the National Cancer Institute·Harri SihtoHeikki Joensuu
Jun 25, 2009·International Journal of Cancer. Journal International Du Cancer·Kishor BhatiaLeona W Ayers
Sep 15, 2009·PLoS Pathogens·Diana V PastranaChristopher B Buck
Nov 26, 2009·Uirusu·Tomoyuki Nakamura, Harutaka Katano
Dec 17, 2009·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Kishor BhatiaJames J Goedert
Jun 15, 2010·Cell Host & Microbe·Rachel M SchowalterChristopher B Buck
Jul 1, 2010·Annals of Oncology : Official Journal of the European Society for Medical Oncology·T TadmorA Polliack
Oct 16, 2010·International Journal of Cancer. Journal International Du Cancer·Marika WaltariHeikki Joensuu
Nov 26, 2010·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Tingting ChenKlaus Hedman
Nov 26, 2010·Nature Reviews. Cancer·Patrick S Moore, Yuan Chang
Mar 10, 2011·Virology Journal·Francesca PaoliniAldo Venuti
Mar 23, 2011·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Kelly G PaulsonPaul Nghiem
May 5, 2011·Seminars in Cutaneous Medicine and Surgery·Timothy S WangJanis M Taube
May 11, 2011·Expert Review of Anticancer Therapy·Jonathan S ZagerJane Messina
May 13, 2011·The Journal of Investigative Dermatology·David SchramaJürgen C Becker

Related Concepts

Malignant Neoplasm of Skin
Immune System
Merkel Cells
Papilloma, Shope
Polyomavirus Infections
Metaplastic Cell Transformation
Oncornaviruses
Carcinoma
Entire Immune System
Merkel Cell Carcinoma

Related Feeds

BK Virus Infection

BK virus infection is a significant complication of modern immunosuppression used in kidney transplantation. Discover the latest research on BK virus infection here.

Related Papers

Journal of the European Academy of Dermatology and Venereology : JEADV
E AceboJ L Díaz-Pérez
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology
Dana E RollisonMichael Pawlita
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology
Markus SchmittMichael Pawlita
Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology
Sherry LeePaul Nghiem
© 2020 Meta ULC. All rights reserved