PMID: 16522997Mar 9, 2006Paper

The metabolic syndrome and its relationship to hypertensive target organ damage

The Journal of Clinical Hypertension
G Mulè, G Cerasola

Abstract

High blood pressure is often associated with various metabolic abnormalities, including abdominal obesity, dyslipidemia, elevated plasma glucose, and insulin resistance, which are the main features of the metabolic syndrome. The metabolic syndrome is extremely common worldwide. This high prevalence is of considerable concern because several studies suggest that the metabolic syndrome carries an increased risk for cardiovascular events. Several lines of evidence seem to indicate that the metabolic syndrome is associated with an increased prevalence of preclinical cardiovascular and renal changes, such as left ventricular hypertrophy, microalbuminuria, impaired aortic elasticity, and early carotid atherosclerosis, most of which are recognized as significant independent predictors of adverse cardiovascular outcomes. It is conceivable that these data may partly explain the high rates of cardiovascular morbidity and mortality that are observed in patients with the metabolic syndrome.

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Citations

Aug 8, 2008·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·G MulèG Cerasola
Oct 16, 2008·Clinical and Experimental Hypertension : CHE·Zuoguang WangZhaosu Wu
Jan 30, 2007·International Journal of Cardiology·Giuseppe MulèGiovanni Cerasola
Aug 9, 2007·Journal of the Cardiometabolic Syndrome·Giuseppe MuléGiovanni Cerasola
Nov 11, 2014·The Journal of Clinical Hypertension·Irina EfimovaYuri Lishmanov
Oct 21, 2011·Arquivos brasileiros de endocrinologia e metabologia·Mariana Santos Felisbino-MendesGustavo Velásquez-Meléndez
Mar 12, 2017·Current Hypertension Reports·Maria MarketouPanos Vardas
Aug 2, 2007·American Journal of Therapeutics·Zafar H IsrailiManuel Velasco
Apr 14, 2019·The Journal of Clinical Hypertension·Steffi ShillyChristine B Sethna
Feb 13, 2008·American Journal of Hypertension·Giuseppe Mulé, Giovanni Cerasola
Jun 1, 2017·The Journal of Clinical Hypertension·Giuseppe MulèSantina Cottone
Apr 16, 2019·International Journal of Hypertension·Juan LiFanrong Liang

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