The metabolic syndrome in relation with the glycemic index and the glycemic load

Physiology & Behavior
R VrolixR P Mensink

Abstract

The metabolic syndrome (MS) is a clustering of metabolic abnormalities that increases the risk to develop chronic diseases such as cardiovascular disease and type 2 diabetes mellitus. Although its precise aetiology is unknown, dietary habits play a major role. Nowadays, more and more attention is paid to the glycemic index (GI) and the glycemic load (GL) of a diet. The GI of a food is a value based on the average increase in blood glucose levels occurring when a 50 g carbohydrate portion of that food is consumed. The GL accounts for the amount of carbohydrate per serving. From reviewing the current literature, we conclude that for healthy and/or overweight subjects the importance of low GI or GL diets in relation to the metabolic syndrome has not been established. One of the reasons is that the diets used in the intervention studies frequently not only differed in GI or GL, but also in fibre, protein and/or fat content. In some of the prospective cohort studies, effects of GI or GL attenuated or even disappeared after correcting for fibre intake. This makes it impossible to ascribe the possible beneficial metabolic effects of low GI or GL diets unequivocally to the GI or GL. The question, therefore, remains open on to what comp...Continue Reading

References

Jan 1, 1985·Endocrine Reviews·R N BergmanM Ader
Feb 12, 1997·JAMA : the Journal of the American Medical Association·J SalmerónW C Willett
Apr 1, 1997·Diabetes Care·J SalmerónW C Willett
Nov 5, 1999·JAMA : the Journal of the American Medical Association·D S LudwigD R Jacobs
Dec 11, 1999·JAMA : the Journal of the American Medical Association·M VisserT B Harris
Dec 20, 2000·Proceedings of the National Academy of Sciences of the United States of America·A H KissebahA G Comuzzie
May 23, 2001·JAMA : the Journal of the American Medical Association·UNKNOWN Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults
Oct 4, 2002·Current Atherosclerosis Reports·Simin Liu, Walter C Willett
Nov 13, 2002·European Journal of Clinical Nutrition·L S AugustinC La Vecchia
Mar 12, 2003·The British Journal of Nutrition·Louise M GoffJimmy D Bell
Jul 29, 2003·Diabetes·Gunnar EngströmFolke Lindgärde
Jun 8, 2004·The Journal of Clinical Endocrinology and Metabolism·Nicola AbateScott M Grundy
Apr 13, 2005·Lancet·Michael StumvollTimon W van Haeften
Apr 20, 2005·Lancet·Robert H EckelPaul Z Zimmet
Jun 1, 2005·Archives of Medical Research·Carlos A Aguilar-SalinasJuan A Rull
Sep 27, 2005·Lancet·K George M M AlbertiUNKNOWN IDF Epidemiology Task Force Consensus Group
Feb 2, 2006·Annals of Medicine·Dianna J MaglianoPaul Z Zimmet
May 24, 2006·Expert Review of Cardiovascular Therapy·Rodolfo PaolettiAndrea Cignarella
Dec 26, 2006·Obesity·Anastassios G PittasAndrew S Greenberg
Jun 1, 2005·Nutrition Research Reviews·F BrounsT M S Wolever

❮ Previous
Next ❯

Citations

Dec 7, 2010·Rheumatology International·Mehmet Tuncay DuruözHülya Deveci
May 20, 2009·Metabolic Syndrome and Related Disorders·Barbara SchiltzJeffrey S Bland
Nov 30, 2010·Journal of the American Dietetic Association·Cari M Kitahara
May 28, 2010·The American Journal of Clinical Nutrition·Ruth Vrolix, Ronald P Mensink
Jun 16, 2011·Physiological Genomics·Evert M van SchothorstJaap Keijer
Jul 22, 2017·Nutrition & Dietetics : the Journal of the Dietitians Association of Australia·Noushin MohammadifardNizal Sarrafzadegan
Oct 3, 2020·Nutrients·Lionel Carneiro, Corinne Leloup

❮ Previous
Next ❯

Related Concepts

Related Feeds

CV Disorders & Type 2 Diabetes

This feed focuses on the association of cardiovascular diseases in patients with type 2 diabetes.

ApoE, Lipids & Cholesterol

Serum cholesterol, triglycerides, apolipoprotein B (APOB)-containing lipoproteins (very low-density lipoprotein (VLDL), immediate-density lipoprotein (IDL), and low-density lipoprotein (LDL), lipoprotein A (LPA)) and the total cholesterol/high-density lipoprotein (HDL) cholesterol ratio are all connected in diseases. Here is the latest research.

Cardiovascular Inflammation

Inflammation plays a significant role in the development of cardiovascular diseases, an understanding of these endogenous processes is critical for evaluating the risks and potential treatment strategies. Discover the latest research on cardiovascular inflammation here.

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.