The MetabolomeExpress Project: enabling web-based processing, analysis and transparent dissemination of GC/MS metabolomics datasets.

BMC Bioinformatics
Adam J CarrollA Harvey Millar

Abstract

Standardization of analytical approaches and reporting methods via community-wide collaboration can work synergistically with web-tool development to result in rapid community-driven expansion of online data repositories suitable for data mining and meta-analysis. In metabolomics, the inter-laboratory reproducibility of gas-chromatography/mass-spectrometry (GC/MS) makes it an obvious target for such development. While a number of web-tools offer access to datasets and/or tools for raw data processing and statistical analysis, none of these systems are currently set up to act as a public repository by easily accepting, processing and presenting publicly submitted GC/MS metabolomics datasets for public re-analysis. Here, we present MetabolomeExpress, a new File Transfer Protocol (FTP) server and web-tool for the online storage, processing, visualisation and statistical re-analysis of publicly submitted GC/MS metabolomics datasets. Users may search a quality-controlled database of metabolite response statistics from publicly submitted datasets by a number of parameters (eg. metabolite, species, organ/biofluid etc.). Users may also perform meta-analysis comparisons of multiple independent experiments or re-analyse public primary da...Continue Reading

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Citations

Aug 7, 2013·Bioinformatics·Nikolas KesslerAlexander Goesmann
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Datasets Mentioned

BETA
AMDIS

Methods Mentioned

BETA
PCA

Software Mentioned

PlantMetabolomics
Google Chrome
Automated Mass - spectral Deconvolution and Identification Sys...
Mozilla Firefox
Raw Data Viewer
XCMS
ResponseFinder
Experiment Explorer
MetAlign
MetaFIND

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