The mini-micro-epididymal sperm aspiration for sperm retrieval: a study of urological outcomes

Human Reproduction
D M NudellP J Turek

Abstract

Epididymal sperm aspiration and in-vitro fertilization (IVF) with intracytoplasmic sperm injection is an established treatment for obstructive azoospermia. Sperm aspiration is performed with either an incision or percutaneously. To control costs, minimize morbidity and retain the advantages of both approaches, we developed a mini-incision technique for epididymal aspiration and here report sperm retrieval and procedure-related outcomes. Twenty-six consecutive patients with obstructive azoospermia underwent epididymal sperm retrieval through a 1 cm incision with local anaesthesia to provide spermatozoa for concurrent IVF cycles. The quality of retrieved spermatozoa, the quantity of spermatozoa cryopreserved as well as anaesthetic requirement, recovery time and patient satisfaction were evaluated. Fresh epididymal spermatozoa were retrieved in 25 of 26 (96%) patients. In one patient, testicular sperm extraction was necessary. Excess motile spermatozoa were cryopreserved in 24 of 26 (92%) patients; a mean total motile count of 4.8x10(6) motile spermatozoa were banked. The procedure was performed with 62% of patients receiving minimal i.v. sedation. Post-procedure recovery was rapid, with a median time to return to work of 2.0 days...Continue Reading

Citations

Jun 10, 2004·Journal of Assisted Reproduction and Genetics·Ulrike ZenkePaul J Turek
Jul 13, 2006·Nature Clinical Practice. Urology·Marc Goldstein, Cigdem Tanrikut
Mar 3, 2001·Human Reproduction·M V MengP J Turek
Sep 30, 2010·Human Reproduction·E A F DancetT M D'Hooghe
Mar 13, 2010·Human Reproduction Update·E A F DancetT M D'Hooghe
Nov 1, 2011·Annual Review of Medicine·Peter J StahlMarc Goldstein
Mar 31, 2015·Asian Journal of Andrology·Tatsuo MoritaAkira Tanaka
Apr 22, 2008·The Urologic Clinics of North America·Richard LeeMarc Goldstein
Jan 9, 2003·The Urologic Clinics of North America·David Shin, Stanton C Honig
Jan 9, 2003·The Urologic Clinics of North America·Carin V HoppsPeter N Schlegel
Sep 7, 2006·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Shai Shefi, Paul J Turek
Sep 5, 1998·The Urologic Clinics of North America·P J TurekP R Carroll
Sep 13, 2014·Urologia·Giorgio FrancoCarlo De Dominicis
Oct 9, 2007·Current Opinion in Urology·Moshe WaldCraig S Niederberger
Dec 4, 2013·Nature Reviews. Urology·Daniel H Shin, Paul J Turek
Feb 11, 2000·Current Opinion in Urology·J M Pomerol
Mar 24, 2009·Fertility and Sterility·Angelo CarpiJeffrey Mechanick

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.