PMID: 8585150Sep 1, 1995Paper

The minimum alveolar concentration of desflurane in cats

Veterinary Surgery : VS
R M McMurphy, D S Hodgson

Abstract

Eight adult cats, 4 male and 4 female, (3.5 +/- 0.9 [SD] kg) were used to determine the minimum alveolar concentration (MAC) of desflurane. Desflurane (DES) anesthesia was induced in a 20 L chamber with an oxygen inflow of 10 L/min and the DES vaporizer set at 18%. After 3.5 +/- 0.5 min, the cats were removed from the chamber and anesthesia was maintained via mask (14% DES, 3L/min O2) until successful intubation. Anesthesia was maintained with DES in oxygen at a flow of at least 200 mL/kg/min through a nonrebreathing circuit. The time from the start of induction to completion of intubation was 6.2 +/- 1.1 min. Esophageal temperature was maintained between 37.8 degrees C and 38.6 degrees C. Hand-collected end-tidal gas samples were obtained from a catheter positioned inside the lumen of the endotracheal tube. Inspired and end-tidal DES concentrations were measured with a Biochem 8100 anesthetic agent monitor that was calibrated with known gas standards and modified to accept hand-collected samples. A constant alveolar concentration of DES was maintained for at least 15 minutes, then a clamp was applied to the tail and the cat observed for gross purposeful movement. The end-tidal DES was then increased (if a positive response) or...Continue Reading

References

Jul 1, 1988·Anesthesiology·B M DoorleyJ L Robinson
May 1, 1974·Journal of Applied Physiology·E P SteffeyE S Munson

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Citations

Mar 18, 2005·Journal of Feline Medicine and Surgery·Almir Pereira SouzaNewton Nunes
May 20, 1999·The Veterinary Clinics of North America. Small Animal Practice·K W Clarke
Nov 7, 2006·Veterinary Anaesthesia and Analgesia·Tamara L GrubbNicole Mailhot
Jun 27, 2018·American Journal of Veterinary Research·Nicolò ColumbanoGiovanni M Careddu
Jul 1, 1997·Veterinary Surgery : VS·F J TendilloI A Gómez de Segura
Jun 17, 2004·American Journal of Veterinary Research·Linda S BarterEugene P Steffey

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