The minimum clinically important difference in SRS-22R total score, appearance, activity and pain domains after surgical treatment of adult spinal deformity

Spine
Charles H CrawfordLeah Y Carreon

Abstract

Longitudinal cohort. To establish minimum clinically important difference (MCID) threshold values for Scoliosis Research Society-22R (SRS-22R) domains in patients with adult spinal deformity undergoing surgical correction. The SRS-22R has been shown to be reliable, valid and responsive to change in patients with adult spinal deformity undergoing surgery. The MCID quantifies a threshold of improvement that is clinically relevant to the patient. Patients in a prospective database who completed the SRS-22R preoperatively and the SRS-30 1 year postoperatively were identified. Answers to the last 8 questions of the SRS-30 were used as anchors to determine MCID for the pain, appearance and activity domains, subscore, and total score using receiver-operating-characteristic curve analysis. Calculations of MCID using distribution-based methods were also done. A total of 1321 patients were included in the analysis; 83% were females and 10% were smokers. Mean age was 53 years. Mean body mass index was 26.3 kg/m. Mean preoperative SRS-22R appearance score was 2.50 improving to 3.62 at 1 year postoperatively (P < 0.001). Mean preoperative SRS-22R activity score was 2.96 and it improved to 3.33 at 1 year postoperatively (P < 0.001). Mean pre...Continue Reading

References

Dec 1, 1989·Controlled Clinical Trials·R JaeschkeG H Guyatt
Feb 20, 2003·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·O HäggUNKNOWN Swedish Lumbar Spine Study Group
Apr 24, 2007·The Spine Journal : Official Journal of the North American Spine Society·Anne G CopayThomas C Schuler
Sep 3, 2008·The Journal of Bone and Joint Surgery. American Volume·Steven D GlassmanLeah Y Carreon

❮ Previous
Next ❯

Citations

Aug 17, 2005·Biomaterials·Jorrit-Jan VerlaanWouter J A Dhert
Sep 24, 2016·The Spine Journal : Official Journal of the North American Spine Society·Vadim Goz, Nikita Lakomkin
Nov 11, 2016·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Elias DiarbakerliPaul Gerdhem
Apr 1, 2017·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Anouar BourghliUNKNOWN European Spine Study Group
Mar 16, 2017·World Neurosurgery·Amit JainUNKNOWN International Spine Study Group
Oct 6, 2017·Current Reviews in Musculoskeletal Medicine·Philip J York, Han Jo Kim
Nov 25, 2017·Journal of Neurosurgery. Spine·Max S RileyMichael P Kelly
Feb 26, 2019·The Journal of Bone and Joint Surgery. American Volume·Michael P KellyKeith H Bridwell
May 11, 2019·Journal of Neurosurgery. Spine·Kazunori HayashiIbrahim Obeid
Sep 26, 2019·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Tetsuhiko MimuraJun Takahashi
Nov 2, 2019·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Kazunori HayashiUNKNOWN European Spine Study Group, ESSG
Mar 2, 2017·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Seung-Jae HyunTae-Ahn Jahng
Feb 18, 2020·Spine Deformity·Ram HaddasIsador Lieberman
Mar 25, 2020·Global Spine Journal·John M IbrahimSigurd H Berven
Jan 11, 2018·Journal of Orthopaedic Surgery and Research·Hao ZhangYongyu Hao
Feb 19, 2019·Global Spine Journal·Sravisht IyerChristopher P Ames
May 10, 2020·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Ahmad M TarawnehNasir A Quraishi
Dec 13, 2016·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·James T BennettPatrick J Cahill
Aug 19, 2020·BMC Musculoskeletal Disorders·Fanqi HuXuesong Zhang
Oct 11, 2020·Spine Deformity·Jeffrey L GumSteven D Glassman

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.