The Mitochondrial Contribution to Animal Performance, Adaptation, and Life-History Variation.

Integrative and Comparative Biology
Wendy R HoodKarine Salin

Abstract

Animals display tremendous variation in their rates of growth, reproductive output, and longevity. While the physiological and molecular mechanisms that underlie this variation remain poorly understood, the performance of the mitochondrion has emerged as a key player. Mitochondria not only impact the performance of eukaryotes via their capacity to produce ATP, but they also play a role in producing heat and reactive oxygen species and function as a major signaling hub for the cell. The papers included in this special issue emerged from a symposium titled "Inside the Black Box: The Mitochondrial Basis of Life-history Variation and Animal Performance." Based on studies of diverse animal taxa, three distinct themes emerged from these papers. (1) When linking mitochondrial function to components of fitness, it is crucial that mitochondrial assays are performed in conditions as close as the intracellular conditions experienced by the mitochondria in vivo. (2) Functional plasticity allows mitochondria to retain their performance, as well as that of their host, over a range of exogenous conditions, and selection on mitochondrial and nuclear-derived proteins can optimize the match between the environment and the bioenergetic capacity o...Continue Reading

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Jul 17, 2018·Integrative and Comparative Biology·W R HoodA N Kavazis

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Citations

Jun 5, 2019·The Journal of Experimental Biology·Wendy R HoodAndreas N Kavazis
Jun 7, 2019·Integrative and Comparative Biology·Wendy R HoodGeoffrey E Hill
Aug 23, 2019·Proceedings. Biological Sciences·Karine SalinNeil B Metcalfe
Feb 6, 2020·Ecology and Evolution·Ming-Long YuanPei-An Tang
Oct 20, 2020·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Christopher R FriesenMats Olsson
Oct 29, 2020·Animal Biotechnology·Israa A Fadhil, Mohammed Baqur S Al-Shuhaib
Dec 3, 2021·Journal of Experimental Zoology. Part A, Ecological and Integrative Physiology·Kaitlyn G HoldenAnne M Bronikowski

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