The mitochondrial genome of the chimpanzee louse, Pediculus schaeffi: insights into the process of mitochondrial genome fragmentation in the blood-sucking lice of great apes

BMC Genomics
Kate HerdRenfu Shao

Abstract

Blood-sucking lice in the genera Pediculus and Pthirus are obligate ectoparasites of great apes. Unlike most bilateral animals, which have 37 mitochondrial (mt) genes on a single circular chromosome, the sucking lice of humans have extensively fragmented mt genomes. The head louse, Pediculus capitis, and the body louse, Pe. humanus, have their 37 mt genes on 20 minichromosomes. The pubic louse, Pthirus pubis, has its 34 mt genes known on 14 minichromosomes. To understand the process of mt genome fragmentation in the sucking lice of great apes, we sequenced the mt genome of the chimpanzee louse, Pe. schaeffi, and compared it with the three human lice. We identified all of the 37 mt genes typical of bilateral animals in the chimpanzee louse; these genes are on 18 types of minichromosomes. Seventeen of the 18 minichromosomes of the chimpanzee louse have the same gene content and gene arrangement as their counterparts in the human head louse and the human body louse. However, five genes, cob, trnS 1 , trnN, trnE and trnM, which are on three minichromosomes in the human head louse and the human body louse, are together on one minichromosome in the chimpanzee louse. Using the human pubic louse, Pt. pubis, as an outgroup for compariso...Continue Reading

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Citations

Apr 2, 2020·Biology Letters·Stephen R Ross, Jesse G Leinwand
Apr 2, 2021·Molecular Phylogenetics and Evolution·Yue ZhangZhihong Li
Apr 4, 2021·Clinical and Experimental Dermatology·P U PatelN J Levell

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Methods Mentioned

BETA
PCR
454 sequencing

Software Mentioned

ClustalX
Wordmatch
Basic Local Alignment Search Tool
SE
Geneious
BLAST
ARWEN
MITOS
tRNAscan

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