The mixability of angiographic contrast with arterial blood

Medical Physics
Baruch B LieberLiliana Cesar

Abstract

Angiographic contrast that is routinely injected into arteries is used not only to evaluate arterial geometry but also in many cases to assess perfusion. The authors conducted two experiments to examine the dispersion of angiographic contrast injected antegradely into an artery under conditions similar to those found in selective (carotid artery) or superselective (circle of Willis) angiography in order to determine the distance from the catheter tip at which the contrast can be considered fully mixed with the blood. A third experiment investigated whether the contrast once mixed with blood will separate from the mixture under the gravitational field due to a density mismatch. Experiment I--Under high-speed angiographic acquisition, a bolus of contrast was injected through a catheter along the flow direction of a blood analog fluid flowing through a straight, long, cylindrical tube. The variation in grayscale intensity along the length of the tube was acquired and modeled as the step response to a second-order system. The distance from the catheter tip at which the contrast mixes with the working fluid, the mixing length, was determined as the length along the tube after which the step response settles to within 3% of the stead...Continue Reading

References

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Citations

Oct 9, 2012·Medical Physics·O BonnefousD Ruijters
Jul 16, 2011·AJNR. American Journal of Neuroradiology·A GangulyR Fahrig
Sep 11, 2010·Contrast Media & Molecular Imaging
Nov 30, 2012·Computational and Mathematical Methods in Medicine·Jürgen EndresArnd Dörfler
Mar 3, 2018·Cardiovascular Engineering and Technology·Brandon KovarovicChander Sadasivan
Dec 15, 2017·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·Ronak DholakiaChander Sadasivan
Nov 10, 2012·Cardiovascular Engineering and Technology·Qing Hao, Baruch B Lieber
Jul 13, 2019·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·Chander SadasivanHenry H Woo
Nov 2, 2019·AJNR. American Journal of Neuroradiology·K L RuedingerC M Strother
Nov 15, 2019·Journal of Neurointerventional Surgery·Chander Sadasivan, David J Fiorella
Nov 28, 2020·AJNR. American Journal of Neuroradiology·K L RuedingerC M Strother
Feb 27, 2021·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·Samantha MarfoglioChander Sadasivan

Related Concepts

Arteriography
Metazoa
Arteries
Blood
Catheterization
Circle of Willis
Radiographic contrast media
Canis familiaris
Glycerin
Gravistimulation

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