PMID: 6536729Sep 1, 1984Paper

The mode of inheritance of a defect in lamination in the hippocampus of BALB/c mice

Journal of Neurogenetics
R S Nowakowski

Abstract

In BALB/c mice the lamination of the pyramidal cell layer of area CA3c of the hippocampus is abnormal in that early-generated neurons are superficial and late-generated neurons are deep. To determine the mode of inheritance of this strain difference, the laminar distribution of mossy fibers and hippocampal pyramidal cells was examined using the Timm's sulfide silver method in BALB/c x C57BL/6 F1 and F2 hybrids, in BALB/cByJ and C57BL/6J mice which were fostered to females of the other strain before receiving their first meal, and in the CXB series of recombinant inbred strains (originally derived using BALB/c and C57BL/6 as progenitor strains). The pattern of hippocampal lamination was classified as "BALB/c-like" if pyramidal cells were present below an intrapyramidal mossy fiber layer or as "B6-like" if only an infrapyramidal mossy fiber layer was present. In both male and female CB6F1 and B6CF1 hybrids the distribution of mossy fibers is BALB/c-like. In 7 of 9 F2 hybrids the distribution was BALB/c-like and in the remaining 2 B6-like. In the cross-fostered mice the pattern was always the same as normally raised mice of the same genotype. Of the recombinant inbred strains, 5 (CXBD, CXBG, CXBH, CXBI, and CXBK) had BALB/c-like h...Continue Reading

References

Jan 1, 1978·Annual Review of Neuroscience·V S Caviness, P Rakic
Jun 1, 1982·Journal of the Neurological Sciences·S E PodusloS Zoller
Feb 10, 1981·The Journal of Comparative Neurology·P Rakic, R S Nowakowski
Oct 22, 1965·Science·R L SidmanJ F Fullier

❮ Previous
Next ❯

Citations

May 21, 2011·Brain Structure & Function·Lutz SlomiankaDavid P Wolfer
Nov 1, 1993·Pharmacology, Biochemistry, and Behavior·N Shanks, H Anisman
Feb 1, 1991·Behavioural Processes·D WahlstenB Bulman-Fleming
Jan 1, 1988·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·A C LuzzattoN Vonesch
Jul 1, 1987·Behavioral and Neural Biology·D F Peeler
Jul 1, 1987·Behavioral and Neural Biology·D F Peeler, R S Nowakowski
Mar 23, 2004·Behavioural Brain Research·Valeria CarolaFranco Mangia
Jun 1, 1987·Child Development·R S Nowakowski
Jul 1, 1986·Journal of Neurogenetics·W E CrusioH Schwegler
Dec 1, 1985·Journal of Neurogenetics·S M RobinsonR L Sidman
Jun 29, 2012·The European Journal of Neuroscience·Naira YeritsyanSiegrid Löwel
Dec 29, 2007·Journal of Neurogenetics·W E CrusioH Schwegler

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.