The moisturizing effect of a wheat extract food supplement on women's skin: a randomized, double-blind placebo-controlled trial

International Journal of Cosmetic Science
S GuillouS Boisnic

Abstract

Ceramides, specific lipid components of the skin, represent 35-40% of the intercellular cement binding cells together and contributing to skin hydration. A wheat extract rich in ceramides and digalactosyl-diglycerides was developed by Hitex in two forms: wheat extract oil (WEO) and wheat extract powder (WEP). In vitro tests and two clinical studies demonstrated promising efficacy results with WEP on skin hydration. To confirm these early results, a double-blind, randomized, placebo-controlled study was carried out on 51 women aged 20-63 years with dry to very dry skin who received either 350 mg of WEO or placebo for 3 months. Evaluation of skin hydration on legs, arms and face, assessed at baseline (D0) and at study end (D84) was performed by the dermatologist using dermatological scores (dryness, roughness, erythema), skin hydration measurement (corneometry) and self-assessment scores (Visual Analogue Scale: VAS). Perceived efficacy was noted by participants throughout the study; tolerability and overall acceptability of the study products were evaluated by the dermatologist and the participants at the end of study. Skin hydration was significantly increased between D0 and D84 on the arms (P < 0.001) and legs (P = 0.012) in th...Continue Reading

References

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Citations

Oct 12, 2012·Cell and Tissue Research·Anthony V Rawlings, Rainer Voegeli
Apr 14, 2017·Skin Pharmacology and Physiology·Efrem N TessemaJohannes Wohlrab
Sep 6, 2012·Phytotherapy Research : PTR·Ken-Ichi Kawano, Kazuo Umemura
Mar 27, 2020·Critical Reviews in Food Science and Nutrition·Xiaoxu WangChanghu Xue
Jun 28, 2018·Analytical and Bioanalytical Chemistry·Efrem N TessemaReinhard H H Neubert
Sep 19, 2012·Journal of Agricultural and Food Chemistry·Manuela ValsecchiSandro Sonnino

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